Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
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Neurotrophic factors in Alzheimer’s disease: role of axonal transportThe E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresomePresenilin-1 regulates the expression of p62 to govern p62-dependent tau degradationUbiquitin-like and ubiquitin-associated domain proteins: significance in proteasomal degradationThe life cycle of the 26S proteasome: from birth, through regulation and function, and onto its deathCullin-RING ligases in regulation of autophagyTau clearance mechanisms and their possible role in the pathogenesis of Alzheimer diseaseParkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's diseaseDefective in mitotic arrest 1 (Dma1) ubiquitin ligase controls G1 cyclin degradation.Huntingtin functions as a scaffold for selective macroautophagyEssential role of sequestosome 1/p62 in regulating accumulation of Lys63-ubiquitinated proteinsTeaching the basics of autophagy and mitophagy to redox biologists--mechanisms and experimental approachesBcl-2-dependent upregulation of autophagy by sequestosome 1/p62 in vitroTRAF6 activation of PI 3-kinase-dependent cytoskeletal changes is cooperative with Ras and is mediated by an interaction with cytoplasmic Src.A genomic screen for activators of the antioxidant response elementRole of the ubiquitin proteasome system in Alzheimer's disease.Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.p62 provides dual cytoprotection against oxidative stress in the retinal pigment epithelium.p62 links the autophagy pathway and the ubiqutin-proteasome system upon ubiquitinated protein degradationPhosphorylation of serine 349 of p62 in Alzheimer's disease brain.p62 improves AD-like pathology by increasing autophagyRegulation of cell proliferation and migration by p62 through stabilization of Twist1.The Intersection of NGF/TrkA Signaling and Amyloid Precursor Protein Processing in Alzheimer's Disease NeuropathologyInclusion body myopathy, Paget's disease of the bone and fronto-temporal dementia: a disorder of autophagyRelationship between tau pathology and neuroinflammation in Alzheimer's disease.Ubiquitin/proteasome pathway impairment in neurodegeneration: therapeutic implicationsThe sequestosome 1/p62 attenuates cytokine gene expression in activated macrophages by inhibiting IFN regulatory factor 8 and TNF receptor-associated factor 6/NF-kappaB activity.p62/sequestosome 1 regulates aggresome formation of pathogenic ataxin-3 with expanded polyglutamineRole of ubiquitin-proteasome-mediated proteolysis in nervous system disease.Rapid degradation of Bim by the ubiquitin-proteasome pathway mediates short-term ischemic tolerance in cultured neurons.Versatile roles of k63-linked ubiquitin chains in trafficking.Long-term treadmill exercise attenuates tau pathology in P301S tau transgenic mice.Promoting autophagic clearance: viable therapeutic targets in Alzheimer's disease.Interferon-stimulated gene 15 (ISG15) and ISG15-linked proteins can associate with members of the selective autophagic process, histone deacetylase 6 (HDAC6) and SQSTM1/p62.Hippocampal endosomal, lysosomal, and autophagic dysregulation in mild cognitive impairment: correlation with aβ and tau pathologyThe toxicity of tau in Alzheimer disease: turnover, targets and potential therapeuticsp62 ubiquitin binding-associated domain mediated the receptor activator of nuclear factor-kappaB ligand-induced osteoclast formation: a new insight into the pathogenesis of Paget's disease of bone.Ubiquitinated proteins enriched from tumor cells by a ubiquitin binding protein Vx3(A7) as a potent cancer vaccine.Decreases in valosin-containing protein result in increased levels of tau phosphorylated at Ser262/356.NMNAT suppresses tau-induced neurodegeneration by promoting clearance of hyperphosphorylated tau oligomers in a Drosophila model of tauopathy.
P2860
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P2860
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
name
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
@ast
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
@en
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
@en-gb
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
@nl
type
label
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
@ast
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
@en
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
@en-gb
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
@nl
prefLabel
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
@ast
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
@en
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
@en-gb
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
@nl
P2860
P3181
P1476
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
@en
P2093
Jeganathan Ramesh Babu
Marie W Wooten
P2860
P304
P3181
P356
10.1111/J.1471-4159.2005.03181.X
P407
P577
2005-07-01T00:00:00Z