Ubiquilin interacts with ubiquitylated proteins and proteasome through its ubiquitin-associated and ubiquitin-like domains
about
Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formationUbiquilin functions in autophagy and is degraded by chaperone-mediated autophagyUbiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machineryUbiquilin and p97/VCP bind erasin, forming a complex involved in ERADAtaxin-3 is a multivalent ligand for the parkin Ubl domainUbiquilin-2 (UBQLN2) binds with high affinity to the C-terminal region of TDP-43 and modulates TDP-43 levels in H4 cells: characterization of inhibition by nucleic acids and 4-aminoquinolinesMutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementiaC9ORF72, the new gene on the block, causes C9FTD/ALS: new insights provided by neuropathologySolution structure and backbone dynamics of an N-terminal ubiquitin-like domain in the GLUT4-regulating protein, TUGUbiquitin-like and ubiquitin-associated domain proteins: significance in proteasomal degradationDimerization of ubiquilin is dependent upon the central region of the protein: evidence that the monomer, but not the dimer, is involved in binding presenilinsThe life cycle of the 26S proteasome: from birth, through regulation and function, and onto its deathUltrastructural studies of ALS mitochondria connect altered function and permeability with defects of mitophagy and mitochondriogenesisRNA-Seq profiling of spinal cord motor neurons from a presymptomatic SOD1 ALS mouseSolution structure of the E3 ligase HOIL-1 Ubl domainALS-linked mutations in ubiquilin-2 or hnRNPA1 reduce interaction between ubiquilin-2 and hnRNPA1Aggresome formation and neurodegenerative diseases: therapeutic implicationsReduced body weight gain in ubiquilin-1 transgenic mice is associated with increased expression of energy-sensing proteinsProtein Homeostasis in Amyotrophic Lateral Sclerosis: Therapeutic Opportunities?A novel ALS-associated variant in UBQLN4 regulates motor axon morphogenesisUbiquilin modifies TDP-43 toxicity in a Drosophila model of amyotrophic lateral sclerosis (ALS).Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductaseProtein aggregation and degradation mechanisms in neurodegenerative diseasesGlucocorticoid modulatory element-binding protein 1 binds to initiator procaspases and inhibits ischemia-induced apoptosis and neuronal injury.Association of UBQLN1 mutation with Brown-Vialetto-Van Laere syndrome but not typical ALS.Ubiquilin 2 is not associated with tau pathologySignature changes in ubiquilin expression in the R6/2 mouse model of Huntington's disease.A fruitful endeavor: modeling ALS in the fruit flyInhibition of Nek2 by small molecules affects proteasome activity.Uncovering the proteome response of the master circadian clock to light using an AutoProteome system.Defective Proteasome Delivery of Polyubiquitinated Proteins by Ubiquilin-2 Proteins Containing ALS Mutations.Ubiquilin 1 Promotes IFN-γ-Induced Xenophagy of Mycobacterium tuberculosisTranscriptomic Analysis of Trout Gill Ionocytes in Fresh Water and Sea Water Using Laser Capture Microdissection Combined with Microarray AnalysisDifferential recruitment of UBQLN2 to nuclear inclusions in the polyglutamine diseases HD and SCA3.Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion.Ubiquitin receptors and protein quality controlThe ubiquitin ligase HERC3 attenuates NF-κB-dependent transcription independently of its enzymatic activity by delivering the RelA subunit for degradationStudies of the role of ubiquitination in the interaction of ubiquilin with the loop and carboxyl terminal regions of presenilin-2A candidate factor that interacts with RF2, a restorer of fertility of Lead rice-type cytoplasmic male sterility in rice.Characterization of Dynamic UbR-Proteasome Subcomplexes by In vivo Cross-linking (X) Assisted Bimolecular Tandem Affinity Purification (XBAP) and Label-free Quantitation.
P2860
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P2860
Ubiquilin interacts with ubiquitylated proteins and proteasome through its ubiquitin-associated and ubiquitin-like domains
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Ubiquilin interacts with ubiqu ...... ted and ubiquitin-like domains
@ast
Ubiquilin interacts with ubiqu ...... ted and ubiquitin-like domains
@en
Ubiquilin interacts with ubiqu ...... ted and ubiquitin-like domains
@en-gb
Ubiquilin interacts with ubiqu ...... ted and ubiquitin-like domains
@nl
type
label
Ubiquilin interacts with ubiqu ...... ted and ubiquitin-like domains
@ast
Ubiquilin interacts with ubiqu ...... ted and ubiquitin-like domains
@en
Ubiquilin interacts with ubiqu ...... ted and ubiquitin-like domains
@en-gb
Ubiquilin interacts with ubiqu ...... ted and ubiquitin-like domains
@nl
prefLabel
Ubiquilin interacts with ubiqu ...... ted and ubiquitin-like domains
@ast
Ubiquilin interacts with ubiqu ...... ted and ubiquitin-like domains
@en
Ubiquilin interacts with ubiqu ...... ted and ubiquitin-like domains
@en-gb
Ubiquilin interacts with ubiqu ...... ted and ubiquitin-like domains
@nl
P2093
P921
P3181
P1433
P1476
Ubiquilin interacts with ubiqu ...... ted and ubiquitin-like domains
@en
P2093
Han Seok Ko
Kazuhiro Tsuruma
Takashi Uehara
Yasuyuki Nomura
P3181
P356
10.1016/J.FEBSLET.2004.04.031
P407
P577
2004-05-21T00:00:00Z