Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation
about
The ubiquilin gene family: evolutionary patterns and functional insightsThe Guanine nucleotide exchange factor kalirin-7 is a novel synphilin-1 interacting protein and modifies synphilin-1 aggregate transport and formationUbiquilin 1 interacts with Orai1 to regulate calcium mobilizationThe recognition of ubiquitinated proteins by the proteasomeThe Ubiquitin-Proteasome System: Potential Therapeutic Targets for Alzheimer's Disease and Spinal Cord InjuryINS-gene mutations: from genetics and beta cell biology to clinical diseaseReduced body weight gain in ubiquilin-1 transgenic mice is associated with increased expression of energy-sensing proteinsInefficient translocation of preproinsulin contributes to pancreatic β cell failure and late-onset diabetes.The ubiquitin-proteasome system in neurodegenerative diseases: precipitating factor, yet part of the solutionProtein aggregation and degradation mechanisms in neurodegenerative diseasesUbiquilin 2 is not associated with tau pathologySignature changes in ubiquilin expression in the R6/2 mouse model of Huntington's disease.Desmin-related cardiomyopathy: an unfolding storyTurmeric and curcumin suppress presenilin 1 protein expression in Jurkat cellsDifferential recruitment of UBQLN2 to nuclear inclusions in the polyglutamine diseases HD and SCA3.Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion.Ubiquitin receptors and protein quality controlThe benefits of local depletion: The centrosome as a scaffold for ubiquitin-proteasome-mediated degradationProteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls.AMP-activated protein kinase: a potential player in Alzheimer's disease.Targeting ubiquilin-1 in Alzheimer's disease.Relationship between amyloid-beta and the ubiquitin-proteasome system in Alzheimer's disease.Involvement of ubiquilin-1 transcript variants in protein degradation and accumulation.Overexpression of Ubiquilin-1 Alleviates Alzheimer's Disease-Caused Cognitive and Motor Deficits and Reduces Amyloid-β Accumulation in Mice.Concordance of Several Subcellular Interactions Initiates Alzheimer's Dementia: Their Reversal Requires Combination Treatment.Inhibitory effect of chloroquine derivatives on presenilin 1 and ubiquilin 1 expression in Alzheimer's disease.Ubiquilin-1 and protein quality control in Alzheimer diseaseALS-associated protein FIG4 is localized in Pick and Lewy bodies, and also neuronal nuclear inclusions, in polyglutamine and intranuclear inclusion body diseases.Association of UBQ-8i polymorphism with Alzheimer's disease in Caucasians: a meta-analysis.PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease.Ubiquilin-1 immunoreactivity is concentrated on Hirano bodies and dystrophic neurites in Alzheimer's disease brains.Cdc48 and ubiquilins confer selective anterograde protein sorting and entry into the multivesicular body in yeast.
P2860
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P2860
Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Alzheimer's disease-associated ...... lation and aggresome formation
@ast
Alzheimer's disease-associated ...... lation and aggresome formation
@en
Alzheimer's disease-associated ...... lation and aggresome formation
@en-gb
Alzheimer's disease-associated ...... lation and aggresome formation
@nl
type
label
Alzheimer's disease-associated ...... lation and aggresome formation
@ast
Alzheimer's disease-associated ...... lation and aggresome formation
@en
Alzheimer's disease-associated ...... lation and aggresome formation
@en-gb
Alzheimer's disease-associated ...... lation and aggresome formation
@nl
prefLabel
Alzheimer's disease-associated ...... lation and aggresome formation
@ast
Alzheimer's disease-associated ...... lation and aggresome formation
@en
Alzheimer's disease-associated ...... lation and aggresome formation
@en-gb
Alzheimer's disease-associated ...... lation and aggresome formation
@nl
P2093
P2860
P50
P921
P3181
P1433
P1476
Alzheimer's disease-associated ...... lation and aggresome formation
@en
P2093
Anne Thomas
Christa J Maynard
Claudia Böttcher
Donna Romano
Jayashree Viswanathan
Kaisa M A Kurkinen
Lars Bertram
Mikko Hiltunen
Oksana Berezovska
P2860
P304
P3181
P356
10.1111/J.1600-0854.2010.01149.X
P407
P577
2011-03-01T00:00:00Z