NHERF1/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligands
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Phosphorylation of PDZ1 domain attenuates NHERF-1 binding to cellular targetsNHERF1/EBP50 controls morphogenesis of 3D colonic glands by stabilizing PTEN and ezrin-radixin-moesin proteins at the apical membraneThe scaffolding protein EBP50 regulates microvillar assembly in a phosphorylation-dependent mannerActivation of nanoscale allosteric protein domain motion revealed by neutron spin echo spectroscopyPDZ domains and their binding partners: structure, specificity, and modificationRegulation of G protein-coupled receptor function by Na+/H+ exchange regulatory factorsAutoinhibitory Interactions between the PDZ2 and C-terminal Domains in the Scaffolding Protein NHERF1A conformational switch in the scaffolding protein NHERF1 controls autoinhibition and complex formation.Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1Structural Insights into Neutrophilic Migration Revealed by the Crystal Structure of the Chemokine Receptor CXCR2 in Complex with the First PDZ Domain of NHERF1PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastomaEzrin induces long-range interdomain allostery in the scaffolding protein NHERF1Organizing the cell cortex: the role of ERM proteinsThe adaptor protein EBP50 is important for localization of the protein kinase A-Ezrin complex in T-cells and the immunomodulating effect of cAMPSip1, the Drosophila orthologue of EBP50/NHERF1, functions with the sterile 20 family kinase Slik to regulate Moesin activity.A regulated complex of the scaffolding proteins PDZK1 and EBP50 with ezrin contribute to microvillar organization.Herpes simplex virus 1 regulatory protein ICP27 undergoes a head-to-tail intramolecular interaction.Immunohistochemical analysis of ezrin-radixin-moesin-binding phosphoprotein 50 in prostatic adenocarcinoma.EBP50 regulates the apoptosis of pancreatic cancer cells by decreasing the expression levels of Bcl-2.Targeted disruption of ephrin B1 in cells of myeloid lineage increases osteoclast differentiation and bone resorption in mice.PTEN Tumor Suppressor Network in PI3K-Akt Pathway ControlHead-to-tail intramolecular interaction of herpes simplex virus type 1 regulatory protein ICP27 is important for its interaction with cellular mRNA export receptor TAP/NXF1.NHERF1/EBP50 is a new marker in colorectal cancer.E6 and E7 from human papillomavirus type 16 cooperate to target the PDZ protein Na/H exchange regulatory factor 1.Drug Transporters and Na+/H+ Exchange Regulatory Factor PSD-95/Drosophila Discs Large/ZO-1 ProteinsStructural basis for NHERF1 PDZ domain bindingActivation of moesin, a protein that links actin cytoskeleton to the plasma membrane, occurs by phosphatidylinositol 4,5-bisphosphate (PIP2) binding sequentially to two sites and releasing an autoinhibitory linker.Ezrin-anchored protein kinase A coordinates phosphorylation-dependent disassembly of a NHERF1 ternary complex to regulate hormone-sensitive phosphate transportHomotypic receptor-receptor interactions regulating Eph signaling.The NHERF2 sequence adjacent and upstream of the ERM-binding domain affects NHERF2-ezrin binding and dexamethasone stimulated NHE3 activity.PTEN inhibits macrophage polarization from M1 to M2 through CCL2 and VEGF-A reduction and NHERF-1 synergism.NHERF1/EBP50 controls lactation by establishing basal membrane polarity complexes with prolactin receptor.A novel splicing mutation in the SLC9A3R1 gene in tumors from ovarian cancer patients.The defining pathology of the new clinical and histopathologic entity ACTA2-related cerebrovascular disease.EBP50 promotes focal adhesion turnover and vascular smooth muscle cells migration.NHERF2 protein mobility rate is determined by a unique C-terminal domain that is also necessary for its regulation of NHE3 protein in OK cells.miR-8 microRNAs regulate the response to osmotic stress in zebrafish embryosThe scaffold protein PDZK1 undergoes a head-to-tail intramolecular association that negatively regulates its interaction with EBP50.The many roles of the highly interactive HSV protein ICP27, a key regulator of infection.Plasticity of PDZ domains in ligand recognition and signaling.
P2860
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P248
Q24294974-50DB70CD-A720-4250-9BFA-93B76F6973CAQ24298305-576E2AA2-BBA0-46FF-B19A-05EF4D03E018Q24302333-8F7BF1D1-2DA2-494F-8715-975F30E2EEE9Q24606859-952922E5-6B3E-4109-88E6-4FF346889503Q24629682-FB5D3193-7564-4B1D-9BF8-F91502630ED7Q26863645-489C31EC-ECD5-4B2F-BDE3-EA5258FB3568Q27655487-C0C744B4-FEC2-41BD-9061-0924DF8AF798Q27658822-77192C5A-CAB1-4B00-A61E-A6CCD5EDD125Q27677356-AB5CCBDC-179F-4271-A5BE-1A6BE08A0DBFQ27680153-FE65A61C-AECB-4C31-A522-04EA277A8E33Q28115966-109E09A5-C19F-46D3-9944-F774C03DFA87Q28251491-7344E101-5EF0-4D6C-BF4F-EB97161EABEBQ28277373-009DAA69-C6C8-44A5-AEDA-9D87855F913FQ28505451-C9E1F27D-7580-4369-AA6E-4919589F3170Q33748611-B42C6F8A-7CEC-4083-8F1D-B47C39649612Q33818470-12CF5219-C230-45B3-AC16-B4AD7EE2F2CAQ33826787-76241D1A-FE08-49FA-9F4A-D5E77F374B7EQ33932203-D30B80EE-DF9C-4272-9F59-2B394C5CCCA1Q33962655-5D4FD633-708E-4722-A457-152AD917A06BQ34189741-1D354D99-C1A1-491A-A54C-2E19DCFA518BQ34202681-7CA290FD-F846-4B1E-9195-B855D73B1A8FQ34285978-53B7E3F4-9D21-486F-B57B-0D100403623FQ34411711-272BFCC4-2FAF-4C58-9781-4E4F237AAF1AQ35140477-5346DC86-0FCE-433C-BDD4-B7489150FEAEQ35795744-52AB520B-C976-4B20-810E-6A00788C0F7AQ35881936-84D8C2B0-BE0E-4DB7-89DA-4A0CBE9D1FA3Q35956572-4BADD206-F74F-4736-94A4-CC1465AAD4FEQ36097909-43604EC0-6373-403F-B45A-E56404CD1760Q36125047-F4FB4762-6276-43F9-98F6-69E7F7BD8013Q36184681-D1540AA3-0241-480A-8DF8-2FE316405D4DQ36211287-FDC00F9B-63CD-4B73-A14C-CF13AE7532E9Q36288731-6153D61A-A582-4ACB-AB92-C77E71398F67Q36334877-6AA79CC6-40E4-4D5C-9C0F-EB0F9A030B5FQ36348596-8F99395F-E373-4E9B-8954-D4E4E0C807C3Q36392890-76AEE2E5-8F0E-42F3-9466-4797AE22C6A8Q36910196-548F2DC5-BBE1-483F-9203-67992645E951Q37237885-3EB100FB-97FB-452B-A075-302470A24F85Q37395713-D2866F32-6870-425A-BF71-EB5BAA926A25Q37955947-DB82A7A0-5653-4010-A233-0C28282024F3Q38009191-ED2EDE0F-70C9-4876-BC96-4443F0544A61
P2860
NHERF1/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligands
description
2007 nî lūn-bûn
@nan
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
NHERF1/EBP50 head-to-tail intr ...... iation with PDZ domain ligands
@ast
NHERF1/EBP50 head-to-tail intr ...... iation with PDZ domain ligands
@en
NHERF1/EBP50 head-to-tail intr ...... iation with PDZ domain ligands
@en-gb
NHERF1/EBP50 head-to-tail intr ...... iation with PDZ domain ligands
@nl
type
label
NHERF1/EBP50 head-to-tail intr ...... iation with PDZ domain ligands
@ast
NHERF1/EBP50 head-to-tail intr ...... iation with PDZ domain ligands
@en
NHERF1/EBP50 head-to-tail intr ...... iation with PDZ domain ligands
@en-gb
NHERF1/EBP50 head-to-tail intr ...... iation with PDZ domain ligands
@nl
prefLabel
NHERF1/EBP50 head-to-tail intr ...... iation with PDZ domain ligands
@ast
NHERF1/EBP50 head-to-tail intr ...... iation with PDZ domain ligands
@en
NHERF1/EBP50 head-to-tail intr ...... iation with PDZ domain ligands
@en-gb
NHERF1/EBP50 head-to-tail intr ...... iation with PDZ domain ligands
@nl
P2093
P2860
P921
P356
P1476
NHERF1/EBP50 head-to-tail intr ...... iation with PDZ domain ligands
@en
P2093
Fabiana C Morales
Henry Adams
Maria-Magdalena Georgescu
Safan Momin
Xiaomin Chen
Yoko Takahashi
P2860
P304
P356
10.1128/MCB.01372-06
P407
P577
2007-04-01T00:00:00Z