A regulated complex of the scaffolding proteins PDZK1 and EBP50 with ezrin contribute to microvillar organization.
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The scaffolding protein EBP50 regulates microvillar assembly in a phosphorylation-dependent mannerActivation of nanoscale allosteric protein domain motion revealed by neutron spin echo spectroscopyLigand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1Open conformation of ezrin bound to phosphatidylinositol 4,5-bisphosphate and to F-actin revealed by neutron scatteringCarbachol-induced MUC17 endocytosis is concomitant with NHE3 internalization and CFTR membrane recruitment in enterocytesEzrin and EBP50 redistribute apically in rat uterine epithelial cells at the time of implantation and in response to cell contactPhosphorylation of a PDZ domain extension modulates binding affinity and interdomain interactions in postsynaptic density-95 (PSD-95) protein, a membrane-associated guanylate kinase (MAGUK).Ezrin-mediated apical integrity is required for intestinal homeostasis.Isotropic actomyosin dynamics promote organization of the apical cell cortex in epithelial cellsDynamics of ezrin and EBP50 in regulating microvilli on the apical aspect of epithelial cells.NHERF2/NHERF3 protein heterodimerization and macrocomplex formation are required for the inhibition of NHE3 activity by carbachol.ERM proteins at a glanceCell cycle dependent association of EBP50 with protein phosphatase 2A in endothelial cellsThe gastrointestinal mucus system in health and diseaseß1 integrin binding phosphorylates ezrin at T567 to activate a lipid raft signalsome driving invadopodia activity and invasionEvidence for a causal link between adaptor protein PDZK1 downregulation and Na⁺/H⁺ exchanger NHE3 dysfunction in human and murine colitisDifferential modulation of the molecular dynamics of the type IIa and IIc sodium phosphate cotransporters by parathyroid hormone.12-O-Tetradecanoylphorbol-13-Acetate Induces Up-Regulated Transcription of Variant 1 but Not Variant 2 of VIL2 in Esophageal Squamous Cell Carcinoma Cells via ERK1/2/AP-1/Sp1 SignalingEzrin regulates microvillus morphogenesis by promoting distinct activities of Eps8 proteins.PDZ interactions regulate rapid turnover of the scaffolding protein EBP50 in microvilli.The function and dynamics of the apical scaffolding protein E3KARP are regulated by cell-cycle phosphorylation.Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cellsTemporal and spatial regulation of ezrin-radixin-moesin-binding phosphoprotein-50-kDa (EBP50) during embryo implantation in mouse uterus.NHERF2 protein mobility rate is determined by a unique C-terminal domain that is also necessary for its regulation of NHE3 protein in OK cells.The tails of apical scaffolding proteins EBP50 and E3KARP regulate their localization and dynamics.Interactome analysis reveals ezrin can adopt multiple conformational states.Phosphatidylinositol 4,5-bisphosphate alters the number of attachment sites between ezrin and actin filaments: a colloidal probe studyPlasticity of the brush border - the yin and yang of intestinal homeostasis.Role of Polarity Proteins in the Generation and Organization of Apical Surface Protrusions.FLT3-driven redox-modulation of Ezrin regulates leukaemic cell migration.Dynamic relocalization of NHERF1 mediates chemotactic migration of ovarian cancer cells toward lysophosphatidic acid stimulation.Both NHERF3 and NHERF2 are necessary for multiple aspects of acute regulation of NHE3 by elevated Ca(2+), cGMP and lysophosphatidic acid.NHERF1 in Microvilli of Vomeronasal Sensory Neurons.
P2860
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P2860
A regulated complex of the scaffolding proteins PDZK1 and EBP50 with ezrin contribute to microvillar organization.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A regulated complex of the sca ...... e to microvillar organization.
@ast
A regulated complex of the sca ...... e to microvillar organization.
@en
type
label
A regulated complex of the sca ...... e to microvillar organization.
@ast
A regulated complex of the sca ...... e to microvillar organization.
@en
prefLabel
A regulated complex of the sca ...... e to microvillar organization.
@ast
A regulated complex of the sca ...... e to microvillar organization.
@en
P2093
P2860
P356
P1476
A regulated complex of the sca ...... e to microvillar organization.
@en
P2093
Anthony Bretscher
Damien Garbett
David P LaLonde
P2860
P304
P356
10.1091/MBC.E10-01-0008
P577
2010-03-17T00:00:00Z