The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization
about
Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimersDifferential protein-protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathwaysPreclinical and clinical studies of the NEDD9 scaffold protein in cancer and other diseasesOrder and disorder in large multi-site docking proteins of the Gab family--implications for signalling complex formation and inhibitor design strategiesRole of ABL family kinases in cancer: from leukaemia to solid tumoursTargeted disruption of leucine-rich repeat kinase 1 but not leucine-rich repeat kinase 2 in mice causes severe osteopetrosisDifferential signaling networks of Bcr-Abl p210 and p190 kinases in leukemia cells defined by functional proteomics.An automated analysis of highly complex flow cytometry-based proteomic data.From Hen House to Bedside: Tracing Hanafusa's Legacy from Avian Leukemia Viruses to SRC to ABL and BeyondOncogenic tyrosine kinases target Dok-1 for ubiquitin-mediated proteasomal degradation to promote cell transformationA53T-alpha-synuclein-overexpression in the mouse nigrostriatal pathway leads to early increase of 14-3-3 epsilon and late increase of GFAPStructure, regulation, signaling, and targeting of abl kinases in cancer.CRAF R391W is a melanoma driver oncogeneRhoA modulates functional and physical interaction between ROCK1 and Erk1/2 in selenite-induced apoptosis of leukaemia cells.JUN dependency in distinct early and late BRAF inhibition adaptation states of melanomaThe function of orthologues of the human Parkinson's disease gene LRRK2 across species: implications for disease modelling in preclinical research.Metabolic labeling of leucine rich repeat kinases 1 and 2 with radioactive phosphate.RegPhos 2.0: an updated resource to explore protein kinase-substrate phosphorylation networks in mammals.Leucine-rich repeat kinase 2 and alpha-synuclein: intersecting pathways in the pathogenesis of Parkinson's disease?Proteomics for systems toxicology.BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia.Phosphoproteomic Analyses of Interleukin 2 Signaling Reveal Integrated JAK Kinase-Dependent and -Independent Networks in CD8(+) T Cells.Alterations of Gab2 signalling complexes in imatinib and dasatinib treated chronic myeloid leukaemia cells.LRRK1 is critical in the regulation of B-cell responses and CARMA1-dependent NF-κB activation.The crystal structure of pseudokinase PEAK1 (Sugen Kinase 269) reveals an unusual catalytic cleft and a novel mode of kinase fold dimerization.Differential signaling through p190 and p210 BCR-ABL fusion proteins revealed by interactome and phosphoproteome analysis.Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins.Inside the 8p23.1 duplication syndrome; eight microduplications of likely or uncertain clinical significance.
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P2860
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization
@ast
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization
@en
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization
@en-gb
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization
@nl
type
label
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization
@ast
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization
@en
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization
@en-gb
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization
@nl
prefLabel
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization
@ast
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization
@en
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization
@en-gb
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization
@nl
P2093
P2860
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P3181
P356
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P1476
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization
@en
P2093
P2860
P2888
P304
P3181
P356
10.1038/ONC.2010.331
P407
P577
2010-08-09T00:00:00Z
P5875
P6179
1051560261