Order and disorder in large multi-site docking proteins of the Gab family--implications for signalling complex formation and inhibitor design strategies
about
Bivalent binding drives the formation of the Grb2-Gab1 signaling complex in a noncooperative mannerStructure and function of Gab2 and its role in cancer (Review)Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide.Models of crk adaptor proteins in cancer.Novel inhibitors of a Grb2 SH3C domain interaction identified by a virtual screenSequence Polymorphism and Intrinsic Structural Disorder as Related to Pathobiological Performance of the Helicobacter pylori CagA OncoproteinThe downstream of tyrosine kinase 7 is reduced in lung cancer and is associated with poor survival of patients with lung cancerCo-occurring protein phosphorylation are functionally associated.Stochastic machines as a colocalization mechanism for scaffold protein functionConformational analysis of isolated domains of Helicobacter pylori CagA.Classifying ten types of major cancers based on reverse phase protein array profiles.Different Epidermal Growth Factor Receptor (EGFR) Agonists Produce Unique Signatures for the Recruitment of Downstream Signaling ProteinsPhospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles.Beyond 'furballs' and 'dumpling soups' - towards a molecular architecture of signaling complexes and networks.Bacterial EPIYA effectors--where do they come from? What are they? Where are they going?What's in a loop?Conformational recognition of an intrinsically disordered protein.Alterations of Gab2 signalling complexes in imatinib and dasatinib treated chronic myeloid leukaemia cells.Understanding the mechanism of binding between Gab2 and the C terminal SH3 domain from Grb2.A ERK/RSK-mediated negative feedback loop regulates M-CSF-evoked PI3K/AKT activation in macrophages.Epidermal growth factor receptors containing a single tyrosine in their C-terminal tail bind different effector molecules and are signaling-competent.Effects of Grb2-associated binding protein 2-specific siRNA on the migration and invasion of MG-63 osteosarcoma cells.Effects of microgravity simulation on zebrafish transcriptomes and bone physiology-exposure starting at 5 days post fertilization.
P2860
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P2860
Order and disorder in large multi-site docking proteins of the Gab family--implications for signalling complex formation and inhibitor design strategies
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Order and disorder in large mu ...... nd inhibitor design strategies
@ast
Order and disorder in large mu ...... nd inhibitor design strategies
@en
Order and disorder in large mu ...... nd inhibitor design strategies
@nl
type
label
Order and disorder in large mu ...... nd inhibitor design strategies
@ast
Order and disorder in large mu ...... nd inhibitor design strategies
@en
Order and disorder in large mu ...... nd inhibitor design strategies
@nl
prefLabel
Order and disorder in large mu ...... nd inhibitor design strategies
@ast
Order and disorder in large mu ...... nd inhibitor design strategies
@en
Order and disorder in large mu ...... nd inhibitor design strategies
@nl
P2860
P3181
P356
P1433
P1476
Order and disorder in large mu ...... nd inhibitor design strategies
@en
P2093
Philip C Simister
Stephan M Feller
P2860
P3181
P356
10.1039/C1MB05272A
P407
P577
2012-01-01T00:00:00Z