Thermodynamics of beta-catenin-ligand interactions: the roles of the N- and C-terminal tails in modulating binding affinity
about
Vinculin regulates cell-surface E-cadherin expression by binding to beta-cateninVE-cadherin and beta-catenin binding dynamics during histamine-induced endothelial hyperpermeabilityAlpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly.An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acidDishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating β-cateninShared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members.Terminal regions of beta-catenin come into viewGetting to the core of cadherin complex function in Caenorhabditis elegansRegulation of Endothelial Adherens Junctions by Tyrosine PhosphorylationThe many faces and functions of β-cateninCrystal Structure of a Full-Length β-CateninThe C. elegans SYS-1 Protein Is a Bona Fide β-CateninStructural and Functional Analysis of the Globular Head Domain of p115 Provides Insight into Membrane TetheringInteractions of Plakoglobin and -Catenin with Desmosomal Cadherins: BASIS OF SELECTIVE EXCLUSION OF - AND -CATENIN FROM DESMOSOMESBiochemical and Structural Characterization of β-Catenin Interactions with Nonphosphorylated and CK2-Phosphorylated Lef-1Structural and Thermodynamic Characterization of Cadherin{middle dot} -Catenin{middle dot} -Catenin Complex FormationThe β-catenin destruction complexThe postsynaptic adenomatous polyposis coli (APC) multiprotein complex is required for localizing neuroligin and neurexin to neuronal nicotinic synapses in vivoFunctional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradationInteraction studies of the human and Arabidopsis thaliana Med25-ACID proteins with the herpes simplex virus VP16- and plant-specific Dreb2a transcription factorsNuclear APCJunctional music that the nucleus hears: cell-cell contact signaling and the modulation of gene activity.Wnt, Hedgehog and junctional Armadillo/beta-catenin establish planar polarity in the Drosophila embryo.Wingless signalling alters the levels, subcellular distribution and dynamics of Armadillo and E-cadherin in third instar larval wing imaginal discs.Platelets, petechiae, and preservation of the vascular wallQuantification of beta-catenin signaling components in colon cancer cell lines, tissue sections, and microdissected tumor cells using reaction monitoring mass spectrometry.Signaling from the adherens junction.The catenin family at a glance.Direct ubiquitination of beta-catenin by Siah-1 and regulation by the exchange factor TBL1.E-cadherin phosphorylation occurs during its biosynthesis to promote its cell surface stability and adhesion.Slow, reversible, coupled folding and binding of the spectrin tetramerization domain.Wnt4 induces nephronic tubules in metanephric mesenchyme by a non-canonical mechanism.A hypomorphic lsd1 allele results in heart development defects in miceDeconstructing the ßcatenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signalingWnt and FGF mediated epithelial-mesenchymal crosstalk during lung development.Purification, crystallization and preliminary X-ray diffraction studies of the β-catenin homolog HMP-2 from Caenorhabditis elegans.Computational modeling of the interplay between cadherin-mediated cell adhesion and Wnt signaling pathwayCytoskeletal mechanisms regulating vascular endothelial barrier function in response to acute lung injuryCadherin cytoplasmic domains inhibit the cell surface localization of endogenous E-cadherin, blocking desmosome and tight junction formation and inducing cell dissociation.A conserved phosphorylation switch controls the interaction between cadherin and β-catenin in vitro and in vivo.
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P2860
Thermodynamics of beta-catenin-ligand interactions: the roles of the N- and C-terminal tails in modulating binding affinity
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Thermodynamics of beta-catenin ...... in modulating binding affinity
@ast
Thermodynamics of beta-catenin ...... in modulating binding affinity
@en
Thermodynamics of beta-catenin ...... in modulating binding affinity
@en-gb
Thermodynamics of beta-catenin ...... in modulating binding affinity
@nl
type
label
Thermodynamics of beta-catenin ...... in modulating binding affinity
@ast
Thermodynamics of beta-catenin ...... in modulating binding affinity
@en
Thermodynamics of beta-catenin ...... in modulating binding affinity
@en-gb
Thermodynamics of beta-catenin ...... in modulating binding affinity
@nl
prefLabel
Thermodynamics of beta-catenin ...... in modulating binding affinity
@ast
Thermodynamics of beta-catenin ...... in modulating binding affinity
@en
Thermodynamics of beta-catenin ...... in modulating binding affinity
@en-gb
Thermodynamics of beta-catenin ...... in modulating binding affinity
@nl
P2860
P921
P3181
P356
P1476
Thermodynamics of beta-catenin ...... in modulating binding affinity
@en
P2093
Andrew H Huber
Hee-Jung Choi
P2860
P304
P3181
P356
10.1074/JBC.M511338200
P407
P577
2006-01-13T00:00:00Z