Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation
about
Phospholipid remodeling and eicosanoid signaling in colon cancer cellsTesting models of the APC tumor suppressor/β-catenin interaction reshapes our view of the destruction complex in Wnt signalingdifferent Roles for the axin interactions with the SAMP versus the second twenty amino acid repeat of adenomatous polyposis coliSelf-association of the APC tumor suppressor is required for the assembly, stability, and activity of the Wnt signaling destruction complex.The two SAMP repeats and their phosphorylation state in Drosophila Adenomatous polyposis coli-2 play mechanistically distinct roles in negatively regulating Wnt signaling.The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the β-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cellsFunctional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epitheliumChemoprevention of intestinal tumorigenesis by the natural dietary flavonoid myricetin in APCMin/+ mice.Induction of miR-3648 Upon ER Stress and Its Regulatory Role in Cell ProliferationTargeting Tankyrase to Fight WNT-dependent Tumours.lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling.Subtle Deregulation of the Wnt-Signaling Pathway Through Loss of Apc2 Reduces the Fitness of Intestinal Stem Cells.Naringin, a natural dietary compound, prevents intestinal tumorigenesis in Apc (Min/+) mouse model.
P2860
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P2860
Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation
description
2013 nî lūn-bûn
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2013 թուականին հրատարակուած գիտական յօդուած
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2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
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2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
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name
Functional comparison of human ...... g beta-catenin for degradation
@ast
Functional comparison of human ...... g beta-catenin for degradation
@en
Functional comparison of human ...... g beta-catenin for degradation
@nl
type
label
Functional comparison of human ...... g beta-catenin for degradation
@ast
Functional comparison of human ...... g beta-catenin for degradation
@en
Functional comparison of human ...... g beta-catenin for degradation
@nl
prefLabel
Functional comparison of human ...... g beta-catenin for degradation
@ast
Functional comparison of human ...... g beta-catenin for degradation
@en
Functional comparison of human ...... g beta-catenin for degradation
@nl
P2093
P2860
P1433
P1476
Functional comparison of human ...... g beta-catenin for degradation
@en
P2093
Jan Gustav Ruppert
Jean Schneikert
Jürgen Behrens
Shree Harsha Vijaya Chandra
Suparna Ray
P2860
P304
P356
10.1371/JOURNAL.PONE.0068072
P407
P50
P577
2013-01-01T00:00:00Z