A vertebrate gene, ticrr, is an essential checkpoint and replication regulator
about
How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?Loading and activation of DNA replicative helicases: the key step of initiation of DNA replicationImprovement of Endurance Based on Muscle Fiber-Type Composition by Treatment with Dietary Apple Polyphenols in RatsThe quaternary structure of the eukaryotic DNA replication proteins Sld7 and Sld3Sld7, an Sld3-associated protein required for efficient chromosomal DNA replication in budding yeast.Cell cycle control in the early embryonic development of aquatic animal speciesMultiple regulatory mechanisms to inhibit untimely initiation of DNA replication are important for stable genome maintenance.TopBP1 deficiency causes an early embryonic lethality and induces cellular senescence in primary cellsProtein phosphatase 2A and Cdc7 kinase regulate the DNA unwinding element-binding protein in replication initiationMDC1 collaborates with TopBP1 in DNA replication checkpoint control.Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication.H3K4me3 demethylation by the histone demethylase KDM5C/JARID1C promotes DNA replication origin firingCyclin-dependent kinase regulates the length of S phase through TICRR/TRESLIN phosphorylation.Enabling association of the GINS protein tetramer with the mini chromosome maintenance (Mcm)2-7 protein complex by phosphorylated Sld2 protein and single-stranded origin DNA.TopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73.Human DNA helicase B interacts with the replication initiation protein Cdc45 and facilitates Cdc45 binding onto chromatinThe Replication Initiation Protein Sld3/Treslin Orchestrates the Assembly of the Replication Fork Helicase during S Phase.Quantitative proteomics reveals the basis for the biochemical specificity of the cell-cycle machineryRole for Rif1 in the checkpoint response to damaged DNA in Xenopus egg extractsA genome-wide RNAi screen identifies core components of the G₂-M DNA damage checkpoint.Emerging players in the initiation of eukaryotic DNA replication.Direct role for the replication protein treslin (Ticrr) in the ATR kinase-mediated checkpoint responseActivation of a human chromosomal replication origin by protein tethering.Akt switches TopBP1 function from checkpoint activation to transcriptional regulation through phosphoserine binding-mediated oligomerization.Helicase activation and establishment of replication forks at chromosomal origins of replication.TopBP1 controls BLM protein level to maintain genome stabilityCDK phosphorylation of SLD-2 is required for replication initiation and germline development in C. elegans.Molecular mechanisms of DNA replication checkpoint activationReplication fork dynamics and the DNA damage response.Control over DNA replication in time and space.Regulating DNA replication in eukarya.Evolutionary conservation of the CDK targets in eukaryotic DNA replication initiation.Mutant p53 perturbs DNA replication checkpoint control through TopBP1 and Treslin.Interaction of Chk1 with Treslin negatively regulates the initiation of chromosomal DNA replication.Mechanisms and regulation of DNA replication initiation in eukaryotes.Mechanisms for initiating cellular DNA replication.Elucidating the DDK-dependent step in replication initiation.ATR maintains select progenitors during nervous system development.GINS and Sld3 compete with one another for Mcm2-7 and Cdc45 binding.Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation.
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P2860
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator
@ast
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator
@en
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator
@en-gb
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator
@nl
type
label
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator
@ast
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator
@en
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator
@en-gb
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator
@nl
prefLabel
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator
@ast
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator
@en
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator
@en-gb
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator
@nl
P2093
P2860
P356
P1433
P1476
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator
@en
P2093
Adam Amsterdam
Christopher L Sansam
Jacqueline A Lees
Melissa L Lau
Nancy Hopkins
Nelly M Cruz
Paul S Danielian
P2860
P304
P356
10.1101/GAD.1860310
P407
P577
2010-01-15T00:00:00Z