A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
about
Bardet-Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 proteinLZTFL1 suppresses gastric cancer cell migration and invasion through regulating nuclear translocation of β-cateninThe intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.Intrinsic protein-protein interaction-mediated and chaperonin-assisted sequential assembly of stable bardet-biedl syndrome protein complex, the BBSomeBBS mutations modify phenotypic expression of CEP290-related ciliopathiesThe centriolar satellite protein AZI1 interacts with BBS4 and regulates ciliary trafficking of the BBSomeThe role of primary cilia in the development and disease of the retinaHow do cilia organize signalling cascades?CEP290 alleles in mice disrupt tissue-specific cilia biogenesis and recapitulate features of syndromic ciliopathiesLZTFL1 suppresses lung tumorigenesis by maintaining differentiation of lung epithelial cells.IFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment.Ectopic expression of human BBS4 can rescue Bardet-Biedl syndrome phenotypes in Bbs4 null miceARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targetingIntraflagellar transport complex structure and cargo interactions.The roles of evolutionarily conserved functional modules in cilia-related trafficking.Nephrocystin proteins NPHP5 and Cep290 regulate BBSome integrity, ciliary trafficking and cargo deliveryLZTFL1 Upregulated by All-Trans Retinoic Acid during CD4+ T Cell Activation Enhances IL-5 Production.miR-106b-5p promotes renal cell carcinoma aggressiveness and stem-cell-like phenotype by activating Wnt/β-catenin signalling.Essential role of the chaperonin CCT in rod outer segment biogenesisHyperphagia: current concepts and future directions proceedings of the 2nd international conference on hyperphagiaCiliopathies: the trafficking connection.Alternative Splicing Shapes the Phenotype of a Mutation in BBS8 To Cause Nonsyndromic Retinitis PigmentosaRegulation of Insulin Receptor Trafficking by Bardet Biedl Syndrome Proteins.BBS4 and BBS5 show functional redundancy in the BBSome to regulate the degradative sorting of ciliary sensory receptors.A Splice Variant of Bardet-Biedl Syndrome 5 (BBS5) Protein that Is Selectively Expressed in Retina.Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.Scoring a backstage pass: mechanisms of ciliogenesis and ciliary access.A novel form of ciliopathy underlies hyperphagia and obesity in Ankrd26 knockout miceThe Meckel syndrome- associated protein MKS1 functionally interacts with components of the BBSome and IFT complexes to mediate ciliary trafficking and hedgehog signalingStructural defects in cilia of the choroid plexus, subfornical organ and ventricular ependyma are associated with ventriculomegaly.Loss of the BBSome perturbs endocytic trafficking and disrupts virulence of Trypanosoma brucei.Cycling of the signaling protein phospholipase D through cilia requires the BBSome only for the export phase.The role of ciliary trafficking in Hedgehog receptor signaling.Identification of proteins that interact with TANK binding kinase 1 and testing for mutations associated with glaucoma.Depletion of BBS Protein LZTFL1 Affects Growth and Causes Retinal Degeneration in Mice.Subretinal gene therapy of mice with Bardet-Biedl syndrome type 1.Mutations in C8ORF37 cause Bardet Biedl syndrome (BBS21)Open Sesame: How Transition Fibers and the Transition Zone Control Ciliary Composition.Exome sequencing of Bardet-Biedl syndrome patient identifies a null mutation in the BBSome subunit BBIP1 (BBS18)Visualizing renal primary cilia.
P2860
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P248
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P2860
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
description
2011 nî lūn-bûn
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2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
@ast
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
@en
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
@en-gb
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
@nl
type
label
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
@ast
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
@en
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
@en-gb
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
@nl
prefLabel
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
@ast
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
@en
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
@en-gb
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
@nl
P2860
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P921
P1433
P1476
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
@en
P2093
Kevin Bugge
Qihong Zhang
P2860
P304
P356
10.1371/JOURNAL.PGEN.1002358
P407
P577
2011-11-03T00:00:00Z