Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
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Altered ribostasis: RNA-protein granules in degenerative disordersEvaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosisConjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUSModel systems of protein-misfolding diseases reveal chaperone modifiers of proteotoxicityFrom animal models to human disease: a genetic approach for personalized medicine in ALSInside out: the role of nucleocytoplasmic transport in ALS and FTLDRecent advances in amyotrophic lateral sclerosisThe extreme N-terminus of TDP-43 mediates the cytoplasmic aggregation of TDP-43 and associated toxicity in vivoPrion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative diseaseToward precision medicine in amyotrophic lateral sclerosisGenotype-phenotype correlations of amyotrophic lateral sclerosisPathological mechanisms underlying TDP-43 driven neurodegeneration in FTLD-ALS spectrum disordersCell biology of spinocerebellar ataxiaConverging mechanisms in ALS and FTD: disrupted RNA and protein homeostasisState of play in amyotrophic lateral sclerosis geneticsThe function of RNA-binding proteins at the synapse: implications for neurodegenerationEvolutionary conservation and expression of human RNA-binding proteins and their role in human genetic diseaseDoes a loss of TDP-43 function cause neurodegeneration?Interaction of RNA with a C-terminal fragment of the amyotrophic lateral sclerosis-associated TDP43 reduces cytotoxicityATX-2, the C. elegans Ortholog of Human Ataxin-2, Regulates Centrosome Size and Microtubule DynamicsAtaxin-2 regulates RGS8 translation in a new BAC-SCA2 transgenic mouse modelRapid flow cytometric measurement of protein inclusions and nuclear trafficking.FUS and TARDBP but not SOD1 interact in genetic models of amyotrophic lateral sclerosisMotor Dysfunctions and Neuropathology in Mouse Models of Spinocerebellar Ataxia Type 2: A Comprehensive ReviewParkinsonism in spinocerebellar ataxiaNon-coding RNA in neural function, disease, and agingFrontotemporal dementia: a bridge between dementia and neuromuscular diseaseEngineering enhanced protein disaggregases for neurodegenerative diseaseCalcium dysregulation links ALS defective proteins and motor neuron selective vulnerabilityThe promise and perils of HDAC inhibitors in neurodegenerationDrosophila as an In Vivo Model for Human Neurodegenerative Disease12q24 locus association with type 1 diabetes: SH2B3 or ATXN2?Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexesTar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissueMicrosatellite interruptions stabilize primate genomes and exist as population-specific single nucleotide polymorphisms within individual human genomesThe roles of post-translational modifications in the context of protein interaction networksPolyQ repeat expansions in ATXN2 associated with ALS are CAA interrupted repeatsAre aberrant phase transitions a driver of cellular aging?Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell deathNeurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
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P2860
Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Ataxin-2 intermediate-length p ...... ed with increased risk for ALS
@ast
Ataxin-2 intermediate-length p ...... ed with increased risk for ALS
@en
Ataxin-2 intermediate-length p ...... ed with increased risk for ALS
@en-gb
Ataxin-2 intermediate-length p ...... ed with increased risk for ALS
@nl
type
label
Ataxin-2 intermediate-length p ...... ed with increased risk for ALS
@ast
Ataxin-2 intermediate-length p ...... ed with increased risk for ALS
@en
Ataxin-2 intermediate-length p ...... ed with increased risk for ALS
@en-gb
Ataxin-2 intermediate-length p ...... ed with increased risk for ALS
@nl
prefLabel
Ataxin-2 intermediate-length p ...... ed with increased risk for ALS
@ast
Ataxin-2 intermediate-length p ...... ed with increased risk for ALS
@en
Ataxin-2 intermediate-length p ...... ed with increased risk for ALS
@en-gb
Ataxin-2 intermediate-length p ...... ed with increased risk for ALS
@nl
P2093
P2860
P3181
P356
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P1476
Ataxin-2 intermediate-length p ...... ed with increased risk for ALS
@en
P2093
Aaron D Gitler
Alice S Chen-Plotkin
Andrew C Elden
Arun Padmanabhan
Dana Clay-Falcone
Denise Juhr
Felix Geser
Georg Auburger
Hyung-Jun Kim
John Q Trojanowski
P2860
P2888
P304
P3181
P356
10.1038/NATURE09320
P407
P577
2010-08-01T00:00:00Z
P5875
P6179
1016044698