The amino-terminal B-Raf-specific region mediates calcium-dependent homo- and hetero-dimerization of Raf.
about
Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signallingIQGAP1 integrates Ca2+/calmodulin and B-Raf signalingThe DHR1 domain of DOCK180 binds to SNX5 and regulates cation-independent mannose 6-phosphate receptor transportThe evolution of combined molecular targeted therapies to advance the therapeutic efficacy in melanoma: a highlight of vemurafenib and cobimetinibSimilar but different: distinct roles for KRAS and BRAF oncogenes in colorectal cancer development and therapy resistanceRas and calcium signaling pathways converge at Raf1 via the Shoc2 scaffold proteinDrosophila Raf's N terminus contains a novel conserved region and can contribute to torso RTK signaling.Understanding the biology of melanoma and therapeutic implicationsQuantitative in vivo fluorescence cross-correlation analyses highlight the importance of competitive effects in the regulation of protein-protein interactionsRecurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.Visualization of growth signal transduction cascades in living cells with genetically encoded probes based on Förster resonance energy transferLRRK2 in Parkinson's disease: function in cells and neurodegeneration.Mechanistic principles of RAF kinase signaling.MAP kinase signaling and inhibition in melanoma.Application of FRET probes in the analysis of neuronal plasticity.Genetically encoded fluorescent biosensors for live-cell visualization of protein phosphorylation.Future Perspective of Single-Molecule FRET Biosensors and Intravital FRET Microscopy.The safety and efficacy of cobimetinib for the treatment of BRAF V600E or V600K melanoma.B- and C-RAF display essential differences in their binding to Ras: the isotype-specific N terminus of B-RAF facilitates Ras binding.
P2860
Q24314807-38ED5B7E-EDC0-40C2-AA3F-85FE2F313BCBQ24323920-9180E82E-AEBE-495C-B0BF-35DAB5A1FE2EQ24656195-ECC0A29B-14D4-4430-B18E-50A400272FE9Q26744335-04830BC2-ECB8-4BAA-B555-DDFF2BD0896AQ26795609-DB5E8F79-E191-422F-AA57-92A82EB9CF40Q33721174-728835B1-032A-427F-9D0B-505305A8073BQ33752617-168FAA6C-D9D9-481C-BEB7-64BBBE776524Q33978378-D80F3EF1-2B32-43CA-9A62-672A1FE50A4DQ34056400-3CC76AA9-DFF2-4B20-A1AA-EDF951E7FA5FQ34354839-8D2B47B6-5227-40EB-A7F7-93098CDB12AEQ37111239-E4225F1E-5E66-4562-AD34-3F997598673CQ37608630-B2241999-7B7F-45AD-BA7F-F4A9E8C11E14Q37785803-E37BE6BF-4B47-4A38-91E5-90F787EA2D9DQ38040353-1081D7CD-7284-4CF8-91E4-C7A58DF8FB5EQ38153370-3A7013B6-6F88-440C-9B67-197B1F794708Q38184156-7E93A720-F7C0-4EB5-A2A4-71D784F172E7Q38836055-F4283BB2-7FFF-4CAE-95F8-617BF217EF83Q38843111-9D111472-F3EB-43C8-AC99-07A1EE0677D1Q40106302-2D2A614F-C279-44FB-A12D-9D67C7A0F367
P2860
The amino-terminal B-Raf-specific region mediates calcium-dependent homo- and hetero-dimerization of Raf.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The amino-terminal B-Raf-speci ...... and hetero-dimerization of Raf
@nl
The amino-terminal B-Raf-speci ...... nd hetero-dimerization of Raf.
@ast
The amino-terminal B-Raf-speci ...... nd hetero-dimerization of Raf.
@en
The amino-terminal B-Raf-speci ...... nd hetero-dimerization of Raf.
@en-gb
type
label
The amino-terminal B-Raf-speci ...... and hetero-dimerization of Raf
@nl
The amino-terminal B-Raf-speci ...... nd hetero-dimerization of Raf.
@ast
The amino-terminal B-Raf-speci ...... nd hetero-dimerization of Raf.
@en
The amino-terminal B-Raf-speci ...... nd hetero-dimerization of Raf.
@en-gb
prefLabel
The amino-terminal B-Raf-speci ...... and hetero-dimerization of Raf
@nl
The amino-terminal B-Raf-speci ...... nd hetero-dimerization of Raf.
@ast
The amino-terminal B-Raf-speci ...... nd hetero-dimerization of Raf.
@en
The amino-terminal B-Raf-speci ...... nd hetero-dimerization of Raf.
@en-gb
P2860
P3181
P356
P1433
P1476
The amino-terminal B-Raf-speci ...... and hetero-dimerization of Raf
@en
P2093
Kenta Terai
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7601241
P407
P577
2006-07-20T00:00:00Z