LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
about
Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleusComponents of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunctionRegulation of ploidy and senescence by the AMPK-related kinase NUAK1Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in DrosophilaTargeting the Mitotic Catastrophe Signaling Pathway in CancerCep55 regulates spindle organization and cell cycle progression in meiotic oocyte.Actin up for Hippo.The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1The tumor suppressor WARTS activates the Omi / HtrA2-dependent pathway of cell deathA crucial role of WW45 in developing epithelial tissues in the mouseThe Hippo Pathway Targets Rae1 to Regulate Mitosis and Organ Size and to Feed Back to Regulate Upstream Components Merlin, Hippo, and WartsCytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cellsElucidation of a universal size-control mechanism in Drosophila and mammalsDual function of the NDR-kinase Dbf2 in the regulation of the F-BAR protein Hof1 during cytokinesisDNA IR-Double Strand Breaks (DSBs) and cellular response via ATMDual function of partitioning-defective 3 in the regulation of YAP phosphorylation and activation.Cdk1 promotes cytokinesis in fission yeast through activation of the septation initiation network.Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP.YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction and HER2 amplificationRegulation of a LATS-homolog by Ras GTPases is important for the control of cell division.The SET domain protein, Set3p, promotes the reliable execution of cytokinesis in Schizosaccharomyces pombe.Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor.Aurora A kinase modulates actin cytoskeleton through phosphorylation of Cofilin: Implication in the mitotic process.Phosphorylation of angiomotin by Lats1/2 kinases inhibits F-actin binding, cell migration, and angiogenesisLATS2 suppresses oncogenic Wnt signaling by disrupting β-catenin/BCL9 interaction.Distinct effects of contraction agonists on the phosphorylation state of cofilin in pulmonary artery smooth muscle.NDR kinases regulate essential cell processes from yeast to humans.Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence.WWP1 E3 ligase targets LATS1 for ubiquitin-mediated degradation in breast cancer cells.Understanding cytokinesis failure.Competing to coordinate cell fate decisions: the MST2-Raf-1 signaling deviceBinding of Kif23-iso1/CHO1 to 14-3-3 is regulated by sequential phosphorylations at two LATS kinase consensus sitesA functional cooperativity between Aurora A kinase and LIM kinase1: implication in the mitotic processLats1 suppresses centrosome overduplication by modulating the stability of Cdc25B.Underexpression of LATS1 TSG in colorectal cancer is associated with promoter hypermethylationA Computational Model of YAP/TAZ Mechanosensing.Epigenetic markers in human gliomas: prospects for therapeutic intervention.Transcriptional activation of the Lats1 tumor suppressor gene in tumors of CUX1 transgenic mice.Cellular senescence: its role in tumor suppression and aging.Mammalian Hippo pathway: from development to cancer and beyond.
P2860
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P2860
LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
@ast
LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
@en
LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
@en-gb
LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
@nl
type
label
LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
@ast
LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
@en
LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
@en-gb
LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
@nl
prefLabel
LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
@ast
LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
@en
LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
@en-gb
LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
@en
P2093
Da-ming Li
Karl L Insogna
Kuanping Yu
Rodney Stewart
Xiaolong Yang
P2860
P2888
P304
P3181
P356
10.1038/NCB1140
P407
P577
2004-07-01T00:00:00Z
P5875
P6179
1024062538