Suppression of alternative lengthening of telomeres by Sp100-mediated sequestration of the MRE11/RAD50/NBS1 complex.
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The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteinsATRX dysfunction induces replication defects in primary mouse cellsTelomere rapid deletion regulates telomere length in Arabidopsis thalianaTelomeres in aging and disease: lessons from zebrafishNucleases in homologous recombination as targets for cancer therapyAlternative mechanisms of telomere lengthening: permissive mutations, DNA repair proteins and tumorigenic progressionThe Role of ATRX in the Alternative Lengthening of Telomeres (ALT) PhenotypeNoncanonical views of homology-directed DNA repairTelomere elongation chooses TERRA ALTernativesWRN loss induces switching of telomerase-independent mechanisms of telomere elongationPML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cellsTelomeric circles: universal players in telomere maintenance?Withaferin-A kills cancer cells with and without telomerase: chemical, computational and experimental evidences.SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome.HP1-mediated formation of alternative lengthening of telomeres-associated PML bodies requires HIRA but not ASF1a.Break-induced DNA replicationLoss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.Telomere maintenance mechanisms in cancer: clinical implicationsSIRT1 contributes to telomere maintenance and augments global homologous recombination.Long telomeres produced by telomerase-resistant recombination are established from a single source and are subject to extreme sequence scramblingLoss of wild-type ATRX expression in somatic cell hybrids segregates with activation of Alternative Lengthening of Telomeres.Disruption of telomere maintenance by depletion of the MRE11/RAD50/NBS1 complex in cells that use alternative lengthening of telomeres.Different expression of alternative lengthening of telomere (ALT)-associated proteins/mRNAs in osteosarcoma cell lines.ATRX represses alternative lengthening of telomeres.Maintenance of very long telomeres by recombination in the Kluyveromyces lactis stn1-M1 mutant involves extreme telomeric turnover, telomeric circles, and concerted telomeric amplification.Stable expression of promyelocytic leukaemia (PML) protein in telomerase positive MCF7 cells results in alternative lengthening of telomeres phenotypeDifferential requirements for DNA repair proteins in immortalized cell lines using alternative lengthening of telomere mechanisms.p53 and disease: when the guardian angel fails.Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells.The telomere-associated homeobox-containing protein TAH1/HMBOX1 participates in telomere maintenance in ALT cellsInduction of alternative lengthening of telomeres-associated PML bodies by p53/p21 requires HP1 proteins.Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination.Assaying and investigating Alternative Lengthening of Telomeres activity in human cells and cancers.Telomerase-independent paths to immortality in predictable cancer subtypes.PML body meets telomere: the beginning of an ALTernate ending?SUMO-1 Gene Silencing Inhibits Proliferation and Promotes Apoptosis of Human Gastric Cancer SGC-7901 Cells.Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX.The many facets of homologous recombination at telomeres.A three-dimensional colocalization RNA interference screening platform to elucidate the alternative lengthening of telomeres pathway.The Epstein-Barr virus nuclear antigen-1 promotes telomere dysfunction via induction of oxidative stress.
P2860
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P2860
Suppression of alternative lengthening of telomeres by Sp100-mediated sequestration of the MRE11/RAD50/NBS1 complex.
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Suppression of alternative len ...... f the MRE11/RAD50/NBS1 complex
@nl
Suppression of alternative len ...... the MRE11/RAD50/NBS1 complex.
@ast
Suppression of alternative len ...... the MRE11/RAD50/NBS1 complex.
@en
Suppression of alternative len ...... the MRE11/RAD50/NBS1 complex.
@en-gb
type
label
Suppression of alternative len ...... f the MRE11/RAD50/NBS1 complex
@nl
Suppression of alternative len ...... the MRE11/RAD50/NBS1 complex.
@ast
Suppression of alternative len ...... the MRE11/RAD50/NBS1 complex.
@en
Suppression of alternative len ...... the MRE11/RAD50/NBS1 complex.
@en-gb
prefLabel
Suppression of alternative len ...... f the MRE11/RAD50/NBS1 complex
@nl
Suppression of alternative len ...... the MRE11/RAD50/NBS1 complex.
@ast
Suppression of alternative len ...... the MRE11/RAD50/NBS1 complex.
@en
Suppression of alternative len ...... the MRE11/RAD50/NBS1 complex.
@en-gb
P2093
P2860
P3181
P1476
Suppression of alternative len ...... f the MRE11/RAD50/NBS1 complex
@en
P2093
Andy C-M Chang
Axel A Neumann
Wei-Qin Jiang
Ze-Huai Zhong
P2860
P304
P3181
P356
10.1128/MCB.25.7.2708-2721.2005
P407
P577
2005-04-01T00:00:00Z