Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
about
COP9 signalosome controls the Carma1-Bcl10-Malt1 complex upon T-cell stimulationDephosphorylation of Carma1 by PP2A negatively regulates T-cell activationLys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activationPKC phosphorylation of TRAF2 mediates IKKalpha/beta recruitment and K63-linked polyubiquitinationUbiquitylation as a Rheostat for TCR Signaling: From Targeted Approaches Toward Global ProfilingThe paracaspase MALT1: biological function and potential for therapeutic inhibitionNF-κB, the first quarter-century: remarkable progress and outstanding questionsStructural Basis for Recognition of Diubiquitins by NEMOCrystal structure of the mucosa-associated lymphoid tissue lymphoma translocation 1 (MALT1) paracaspase regionStructural analysis of phenothiazine derivatives as allosteric inhibitors of the MALT1 paracaspaseRegulation of inflammatory and antiviral signaling by A20.Protein kinase C-δ negatively regulates T cell receptor-induced NF-κB activation by inhibiting the assembly of CARMA1 signalosomeTargeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell LymphomaThe let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2Usp12 stabilizes the T-cell receptor complex at the cell surface during signalingThe protein kinase C-responsive inhibitory domain of CARD11 functions in NF-kappaB activation to regulate the association of multiple signaling cofactors that differentially depend on Bcl10 and MALT1 for association.YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κBAlternative splicing of MALT1 controls signalling and activation of CD4(+) T cellsAuto-ubiquitination-induced degradation of MALT1-API2 prevents BCL10 destabilization in t(11;18)(q21;q21)-positive MALT lymphoma.Signaling to NF-kappaB: regulation by ubiquitination.The CBM signalosome: potential therapeutic target for aggressive lymphoma?Oncogenic activation of NF-kappaB.Participation of the cell polarity protein PALS1 to T-cell receptor-mediated NF-κB activationCARMA1-mediated NF-kappaB and JNK activation in lymphocytes.NF-κB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-κB activationAntigen receptor signaling to NF-kappaB via CARMA1, BCL10, and MALT1.Oncogenic CARD11 mutations induce hyperactive signaling by disrupting autoinhibition by the PKC-responsive inhibitory domainThe CARD11-BCL10-MALT1 (CBM) signalosome complex: Stepping into the limelight of human primary immunodeficiency.Control of CXCR2 activity through its ubiquitination on K327 residue.MALT1 auto-proteolysis is essential for NF-κB-dependent gene transcription in activated lymphocytes.The API2-MALT1 fusion exploits TNFR pathway-associated RIP1 ubiquitination to promote oncogenic NF-κB signaling.ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress.Negative regulation of NF-κB signaling in T lymphocytes by the ubiquitin-specific protease USP34Protein ubiquitination in lymphoid malignancies.Malt1 protease inactivation efficiently dampens immune responses but causes spontaneous autoimmunity.Monoubiquitination and activity of the paracaspase MALT1 requires glutamate 549 in the dimerization interfaceMALT1-ubiquitination triggers non-genomic NF-κB/IKK signaling upon platelet activationCombined immunodeficiency due to MALT1 mutations, treated by hematopoietic cell transplantation.NF-κB signaling pathways regulated by CARMA family of scaffold proteins.MALT1 Protease Activity Is Required for Innate and Adaptive Immune Responses.
P2860
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P2860
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
@ast
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
@en
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
@en-gb
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
@nl
type
label
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
@ast
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
@en
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
@en-gb
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
@nl
prefLabel
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
@ast
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
@en
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
@en-gb
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
@nl
P2093
P2860
P3181
P356
P1433
P1476
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
@en
P2093
Andrea Oeckinghaus
Claus Scheidereit
Elmar Wegener
Seda Cöl Arslan
Verena Welteke
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7601897
P407
P577
2007-11-14T00:00:00Z