NF-κB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-κB activation - Test2 - elhamkhani - TriplyDB

NF-κB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-κB activation

NF-κB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-κB activation

http://www.wikidata.org/entity/Q33915312

about

Ubiquitin modifications Misframed ubiquitin and impaired protein quality control: an early event in Alzheimer's disease Regulation of NF-κB by ubiquitination Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti UBXD Proteins: A Family of Proteins with Diverse Functions in Cancer Molecular basis for specificity of the Met1-linked polyubiquitin signal Quantification of cellular NEMO content and its impact on NF-κB activation by genotoxic stress Arabidopsis ALIX is required for the endosomal localization of the deubiquitinating enzyme AMSH3.Individual Src-family tyrosine kinases direct the degradation or protection of the clock protein Timeless via differential ubiquitylation.YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB Oncogenic CARMA1 couples NF-κB and β-catenin signaling in diffuse large B-cell lymphomas.Alternative splicing of MALT1 controls signalling and activation of CD4(+) T cells NF-κB Pathway in Autoinflammatory Diseases: Dysregulation of Protein Modifications by Ubiquitin Defines a New Category of Autoinflammatory Diseases.Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC.The IκB kinase complex in NF-κB regulation and beyond.Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies.Protein-protein interaction modulator drug discovery: past efforts and future opportunities using a rich source of low- and high-throughput screening assays.CYLD-mediated signaling and diseases.Inhibition of Canonical NF-κB Signaling by a Small Molecule Targeting NEMO-Ubiquitin Interaction SHARPIN is a key regulator of immune and inflammatory responses Legume receptors perceive the rhizobial lipochitin oligosaccharide signal molecules by direct binding.Diversification of the structural determinants of fibroblast growth factor-heparin interactions: implications for binding specificity Recruitment of A20 by the C-terminal domain of NEMO suppresses NF-κB activation and autoinflammatory disease.Ubiquitin regulates caspase recruitment domain-mediated signaling by nucleotide-binding oligomerization domain-containing proteins NOD1 and NOD2.A20/TNFAIP3 inhibits NF-κB activation induced by the Kaposi's sarcoma-associated herpesvirus vFLIP oncoprotein.Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1.EGLN3 inhibition of NF-κB is mediated by prolyl hydroxylase-independent inhibition of IκB kinase γ ubiquitination Innate immune-directed NF-κB signaling requires site-specific NEMO ubiquitination.Deficiency in p53 is required for doxorubicin induced transcriptional activation of NF-кB target genes in human breast cancer Protein Quality Control by Molecular Chaperones in Neurodegeneration.Ubiquitin pathways in neurodegenerative disease.Formation and removal of poly-ubiquitin chains in the regulation of tumor necrosis factor-induced gene activation and cell death.Molluscum Contagiosum Virus MC159 Abrogates cIAP1-NEMO Interactions and Inhibits NEMO Polyubiquitination.Mutation of nonessential cysteines shows that the NF-κB essential modulator forms a constitutive noncovalent dimer that binds IκB kinase-β with high affinity.Recruitment of TBK1 to cytosol-invading Salmonella induces WIPI2-dependent antibacterial autophagy.Analysis of nuclear factor-κB (NF-κB) essential modulator (NEMO) binding to linear and lysine-linked ubiquitin chains and its role in the activation of NF-κB.Two-sided ubiquitin binding of NF-κB essential modulator (NEMO) zinc finger unveiled by a mutation associated with anhidrotic ectodermal dysplasia with immunodeficiency syndrome.Target specificity of the E3 ligase LUBAC for ubiquitin and NEMO relies on different minimal requirements.Molecular Determinants of Scaffold-induced Linear Ubiquitinylation of B Cell Lymphoma/Leukemia 10 (Bcl10) during T Cell Receptor and Oncogenic Caspase Recruitment Domain-containing Protein 11 (CARD11) Signaling.The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis.

P2860

Q26751380-CE46C10D-13AE-43BD-86EF-DCF685E98B3D Q26782999-BC244CE1-FE07-4A1F-8400-233105EA0E25 Q27024099-AAA93782-9F28-4DAF-8189-EADEB2AD3DFD Q27330416-B105F269-B428-4F88-9A86-6712AD21B4C9 Q28069036-8BF45DC3-E27F-4388-8107-EBBE7EEB521D Q28072740-C1198658-2395-42E1-A8FB-A0D94221A052 Q28543866-722E5D51-8C58-436B-8AD2-7A044DA70FA6 Q30009106-E44986D1-9631-4350-8EAF-6F6268A33F3E Q30009956-A2AC2096-5B35-436F-B237-AD707B842129 Q30361285-058234B5-B68A-4399-8562-25BAF2C9241D Q30375911-CA2271FE-6CFE-427C-86F0-1EDEDA8DE73A Q30385214-C644980B-855F-4920-858A-5366D1FB1264 Q33576114-FC7AEDFD-48DA-4025-96F8-7E97E5FEAA2E Q34270866-1757D65F-F117-49EA-8A93-B27C9F9CDC42 Q35001723-774C771A-0723-469D-A8FB-3BDEA8A222CD Q35152946-76808218-DB1E-435F-8A8C-FE34B5777F64 Q35397776-E5BC16DD-E78B-4703-B110-697323FC3D95 Q35565726-6A3289D8-D2FF-49BD-BA63-698060E219B3 Q35887748-621995DD-9045-4038-8965-D7F75B3CE5A6 Q36110258-EC89A8A2-B779-49E5-8586-EEF7DF728D53 Q36187377-1DFB2EA6-8171-4FB6-8AA3-D70431A4A608 Q36407996-7A0B0CD6-C065-4389-9F27-6E293816306A Q36598807-6F7F003A-7C18-4A99-9A0E-5D8307424601 Q36666117-649252A9-3E69-412C-975A-872D6C819E3D Q36673788-C0887483-3B70-4D31-88CC-184470D13323 Q36985668-FE784AD6-7939-4BD4-B2C8-AF7F7F99C510 Q37036380-95CC0CC4-7F9C-46B8-B1BC-B026F73DA308 Q37350277-0DA7B4C0-01CA-44B9-97B3-ADF4B581C925 Q37649660-E841529D-D6BB-4A08-B94A-00260771ACD1 Q37739093-09C501BC-23BA-4896-8CE1-0F4DBCFFC355 Q38234883-3C5B4572-2A0C-485A-A93F-24866B8F6DF0 Q38691490-B4CA55BE-689E-4CCD-9247-C1C1E71FD8DE Q38703178-D47E63A2-33A4-4B72-B9BC-5E360FE06DC4 Q40192267-C2461F84-BB9C-40D4-BD2B-0CDBAECDCC17 Q40628113-51D0CFEB-2DE6-4841-96B4-9077F8DA55EA Q42043277-00E3667B-4537-4348-8375-7DB6623D8FCD Q42732317-6477A8BF-1289-4296-87AC-DCBFEFA44012 Q42925205-81B4883F-F990-47FE-8ACF-B16BA5E5A213 Q46356873-93203710-8A1F-4E97-A20B-510F071EB577 Q47134414-6DA72B09-D069-49DB-A5E6-BAD0D21F7041

P2860

NF-κB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-κB activation

http://www.wikidata.org/entity/Q33915312

description

2011 nî lūn-bûn

@nan

2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年学术文章

@wuu

2011年学术文章

@zh-cn

2011年学术文章

@zh-hans

2011年学术文章

@zh-my

2011年学术文章

@zh-sg

2011年學術文章

@yue

name

NF-κB essential modulator (NEM ...... ontributes to NF-κB activation

@ast

NF-κB essential modulator (NEM ...... ontributes to NF-κB activation

@en

type

label

NF-κB essential modulator (NEM ...... ontributes to NF-κB activation

@ast

NF-κB essential modulator (NEM ...... ontributes to NF-κB activation

@en

prefLabel

NF-κB essential modulator (NEM ...... ontributes to NF-κB activation

@ast

NF-κB essential modulator (NEM ...... ontributes to NF-κB activation

@en

P1433

Q33915312-9E1AD45B-0CEC-4142-8CE1-D56B3961D8A8

P1476

Q33915312-0B2C4F0B-7E8E-4FBC-8B3C-814F7D9B6D05

P2093

Q33915312-47901CBA-D21E-4160-A0CD-03CAC4109741

Q33915312-5186A94A-6A2B-40D1-B224-BB39919F249C

Q33915312-66E549D8-A363-4EE3-929C-7CBCC8164C0C

Q33915312-736BFAF0-678A-4CAB-8B24-B0F2D37AEB4D

Q33915312-7FD925BD-7979-4601-BF65-AB95476A043F

Q33915312-C4C3A020-F001-4626-A81A-8CEF68B5E2CA

Q33915312-D514A82F-1456-4BCB-B732-BA85E0191DEE

P2860

Q33915312-127F61BB-CF98-4B3F-B59E-0EA58A947BAD

Q33915312-1480E054-5B98-4ADD-B847-B2E2721C7DB2

Q33915312-20B34A02-506D-4D83-9BE8-E0379A030F0E

Q33915312-2A67598F-50ED-4387-BF58-D741E69C12B2

Q33915312-36ADCA05-8465-47B5-9095-5FF7771A5E22

Q33915312-3B63126D-5234-4BD2-B57C-A64B64F3595D

Q33915312-4075FF3E-F51D-425D-B481-0C11A40F0C03

Q33915312-5471EE46-1D06-48CC-AAC8-C6A6023F63F0

Q33915312-5BE50E3A-BDA6-4691-8E69-2FBBAEC4B350

Q33915312-5DEDCE02-9F9D-4714-A3C8-5F730A52BCAE

P304

Q33915312-8A0C2ED1-FF51-4695-8DA2-F2DDEDE2B001

P31

Q33915312-F666B29C-87DB-4013-9E83-5541FA295CB3

P356

Q33915312-98C5A526-95E5-4FF2-B154-3A1DA1AE4341

P407

Q33915312-91B18B68-99F2-4C7D-A285-127B7EA9148A

P433

Q33915312-4E9AA0E0-FB57-4E27-98FC-53440B27CE02

P478

Q33915312-EB7F4BA6-CEFC-4316-B0FC-07C241B7B84D

P50

Q33915312-093C9605-7525-442D-AC83-761275C05179

Q33915312-41BED2C9-CB2B-475A-9549-0677096448FA

Q33915312-6470D868-EF7C-42B2-950D-D80EA98788CD

P577

Q33915312-2BDD7596-1A81-4999-97C8-88B1333856F9

P698

Q33915312-96C20443-6EA4-4B97-BF1D-CDC0B9C23583

P921

Q33915312-38249068-C953-4609-BFAF-5F04E1224A8B

P932

Q33915312-81684E96-DB2B-4919-ADBD-545AC6915D84

P356

JBC.M111.233163

P1433

Journal of Biological Chemistry

P1476

NF-κB essential modulator (NEM ...... ontributes to NF-κB activation

@en

P2093

Daniel Nagel

http://www.w3.org/2001/XMLSchema#string

Marc Schmidt-Supprian

http://www.w3.org/2001/XMLSchema#string

Moritz Metlitzky

http://www.w3.org/2001/XMLSchema#string

Richard A Griesbach

http://www.w3.org/2001/XMLSchema#string

Scarlett Dornauer

http://www.w3.org/2001/XMLSchema#string

Tim M Wanger

http://www.w3.org/2001/XMLSchema#string

Wolfgang Beisker

http://www.w3.org/2001/XMLSchema#string

P2860

Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction

Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation

Linear ubiquitination prevents inflammation and regulates immune signalling

SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

Dephosphorylation of Carma1 by PP2A negatively regulates T-cell activation

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain

Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain

P304

26107-26117

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M111.233163

http://www.w3.org/2001/XMLSchema#string

P407

P433

29

http://www.w3.org/2001/XMLSchema#string

P478

286

http://www.w3.org/2001/XMLSchema#string

P50

Daniel Krappmann

Marc Schmidt-Supprian

P577

2011-05-26T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

21622571

http://www.w3.org/2001/XMLSchema#string

P921

P932

3138271

http://www.w3.org/2001/XMLSchema#string