p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2
about
Pyruvate dehydrogenase kinase as a novel therapeutic target in oncologyTargeting Tumor Metabolism for Cancer Treatment: Is Pyruvate Dehydrogenase Kinases (PDKs) a Viable Anticancer Target?Is cancer a metabolic disease?Tumor suppressor p53 and its mutants in cancer metabolismTwo-way communication between the metabolic and cell cycle machineries: the molecular basisChanging perspective on oncometabolites: from metabolic signature of cancer to tumorigenic and immunosuppressive agentsThe role of the p53 tumor suppressor in metabolism and diabetesROS homeostasis and metabolism: a critical liaison for cancer therapyp53 and mitochondrial function in neurons.The Warburg effect in tumor progression: mitochondrial oxidative metabolism as an anti-metastasis mechanismThe effect of low dose rate on metabolomic response to radiation in mice.Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors.Cross-Talk between Carbon Metabolism and the DNA Damage Response in S. cerevisiae.Acute Tumor Lactate Perturbations as a Biomarker of Genotoxic Stress: Development of a Biochemical Model.The regulation of cellular metabolism by tumor suppressor p53.p53-Dependent regulation of metabolic function through transcriptional activation of pantothenate kinase-1 gene.KDM4A Coactivates E2F1 to Regulate the PDK-Dependent Metabolic Switch between Mitochondrial Oxidation and GlycolysisMetabolic regulation by p53 family members.E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activityMonoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice.Genetic polymorphisms in glycolytic pathway are associated with the prognosis of patients with early stage non-small cell lung cancerp53 and regulation of tumor metabolism.p53 coordinates DNA repair with nucleotide synthesis by suppressing PFKFB3 expression and promoting the pentose phosphate pathway.Cited2 is required for the maintenance of glycolytic metabolism in adult hematopoietic stem cells.Role of carbohydrate response element-binding protein (ChREBP) in generating an aerobic metabolic phenotype and in breast cancer progression.Cancer cell metabolism and the modulating effects of nitric oxide.Is p53 Involved in Tissue-Specific Insulin Resistance Formation?Cancer cell metabolism: one hallmark, many faces.Regulation of pyruvate metabolism in metabolic-related diseases.The cytoplasmic side of p53's oncosuppressive activities.Metabolic modulation of cancer: a new frontier with great translational potential.The pyruvate dehydrogenase complex in cancer: An old metabolic gatekeeper regulated by new pathways and pharmacological agents.Uncovering metabolism in rhabdomyosarcoma.Mitochondria and the hallmarks of cancer.The emerging role and targetability of the TCA cycle in cancer metabolism.Metabolic alterations accompanying oncogene-induced senescence.Regulation of Cellular Metabolism and Hypoxia by p53.Retinoic acid-related orphan receptor alpha reprograms glucose metabolism in glutamine-deficient hepatoma cells.The p53 family orchestrates the regulation of metabolism: physiological regulation and implications for cancer therapy.Metabolic alterations during the growth of tumour spheroids.
P2860
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P2860
p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2
@ast
p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2
@en
p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2
@en-gb
p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2
@nl
type
label
p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2
@ast
p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2
@en
p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2
@en-gb
p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2
@nl
prefLabel
p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2
@ast
p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2
@en
p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2
@en-gb
p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2
@nl
P3181
P1433
P1476
p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2
@en
P2093
Chris R Harris
Tanupriya Contractor
P3181
P356
10.1158/0008-5472.CAN-11-1215
P407
P577
2012-01-15T00:00:00Z