Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus
about
CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesisSeveral distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locusUbiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressorInteraction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cellsEpigenetic regulation of the INK4b-ARF-INK4a locus: in sickness and in healthCellular senescence and tumor suppressor gene p16The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cellsRecognition and Specificity Determinants of the Human Cbx ChromodomainsThe H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescenceA novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1Investigation of the relationship between chromobox homolog 8 and nucleus pulposus cells degeneration in rat intervertebral discRNA-seq analysis reveals different dynamics of differentiation of human dermis- and adipose-derived stromal stem cellsQuantitative analysis of ChIP-seq data uncovers dynamic and sustained H3K4me3 and H3K27me3 modulation in cancer cells under hypoxiaThe polycomb repressive complex 2 is a potential target of SUMO modifications.Inhibition of CtBP1 activity by Akt-mediated phosphorylation.Changes in the distributions and dynamics of polycomb repressive complexes during embryonic stem cell differentiationNovel motifs distinguish multiple homologues of Polycomb in vertebrates: expansion and diversification of the epigenetic toolkitHistone H3 lysine 27 methylation asymmetry on developmentally-regulated promoters distinguish the first two lineages in mouse preimplantation embryos.Genome-scale transcriptional analysis reveals key genes associated with the development of type II diabetes in mice.Polycomb CBX7 directly controls trimethylation of histone H3 at lysine 9 at the p16 locus.Signatures of polycomb repression and reduced H3K4 trimethylation are associated with p15INK4b DNA methylation in AML.Epigenetic regulation by polycomb group complexes: focus on roles of CBX proteinsPolycomb and trithorax opposition in development and disease.MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation.The histone demethylase Jarid1b (Kdm5b) is a novel component of the Rb pathway and associates with E2f-target genes in MEFs during senescence.Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes.CBX8, a novel DNA repair protein, promotes tumorigenesis in human esophageal carcinoma.REST-mediated recruitment of polycomb repressor complexes in mammalian cells.Genotranscriptomic meta-analysis of the Polycomb gene CBX2 in human cancers: initial evidence of an oncogenic role.The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.Polycomb group complexes--many combinations, many functions.Regulation of senescence in cancer and aging.Structure and mechanisms of lysine methylation recognition by the chromodomain in gene transcription.Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer.Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the Ink4a/Arf locusEfficient immortalization of primary nasopharyngeal epithelial cells for EBV infection study.Altered expression of polycomb group genes in glioblastoma multiforme.Polycomb protein SCML2 regulates the cell cycle by binding and modulating CDK/CYCLIN/p21 complexes.The histone lysine demethylase JMJD3/KDM6B is recruited to p53 bound promoters and enhancer elements in a p53 dependent manner.Transcriptional repression of Sin3B by Bmi-1 prevents cellular senescence and is relieved by oncogene activation
P2860
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P2860
Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus
description
2007 nî lūn-bûn
@nan
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Bypass of senescence by the po ...... binding to the INK4A-ARF locus
@ast
Bypass of senescence by the po ...... binding to the INK4A-ARF locus
@en
Bypass of senescence by the po ...... binding to the INK4A-ARF locus
@en-gb
Bypass of senescence by the po ...... binding to the INK4A-ARF locus
@nl
type
label
Bypass of senescence by the po ...... binding to the INK4A-ARF locus
@ast
Bypass of senescence by the po ...... binding to the INK4A-ARF locus
@en
Bypass of senescence by the po ...... binding to the INK4A-ARF locus
@en-gb
Bypass of senescence by the po ...... binding to the INK4A-ARF locus
@nl
prefLabel
Bypass of senescence by the po ...... binding to the INK4A-ARF locus
@ast
Bypass of senescence by the po ...... binding to the INK4A-ARF locus
@en
Bypass of senescence by the po ...... binding to the INK4A-ARF locus
@en-gb
Bypass of senescence by the po ...... binding to the INK4A-ARF locus
@nl
P2860
P50
P3181
P356
P1433
P1476
Bypass of senescence by the po ...... binding to the INK4A-ARF locus
@en
P2093
Emmanuelle Trinh
Nikolaj Dietrich
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7601632
P407
P50
P577
2007-03-21T00:00:00Z