The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence
about
FOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinomaInterplay between Homeobox proteins and Polycomb repressive complexes in p16INK⁴a regulationH3K27 demethylation by JMJD3 at a poised enhancer of anti-apoptotic gene BCL2 determines ERα ligand dependencyEpigenetic regulation of the INK4b-ARF-INK4a locus: in sickness and in healthCovalent histone modifications--miswritten, misinterpreted and mis-erased in human cancersLong non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor geneA histone demethylase is necessary for regeneration in zebrafishHistone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RASROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related DiseasesHypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related DiseasesOxidative stress and epigenetic regulation in ageing and age-related diseasesEpigenetic plasticity: a central regulator of epithelial-to-mesenchymal transition in cancerThe C. elegans H3K27 demethylase UTX-1 is essential for normal development, independent of its enzymatic activityCellular defense against latent colonization foiled by human cytomegalovirus UL138 protein.Integrating Epigenomics into the Understanding of Biomedical InsightJMJD3 as an epigenetic regulator in development and diseaseA KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotypeThe histone demethylase UTX enables RB-dependent cell fate controlA kinase-independent function of CDK6 links the cell cycle to tumor angiogenesisUTX and UTY demonstrate histone demethylase-independent function in mouse embryonic developmentHistone demethylase Jumonji D3 (JMJD3) as a tumor suppressor by regulating p53 protein nuclear stabilizationA novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1Alterations in chromatin are associated with increases in collagen III expression in aging nephropathyPostnatal development, maturation and aging in the mouse cochlea and their effects on hair cell regeneration.JMJD3 suppresses stem cell-like characteristics in breast cancer cells by downregulation of Oct4 independently of its demethylase activity.Epigenetic repression of p16(INK4A) by latent Epstein-Barr virus requires the interaction of EBNA3A and EBNA3C with CtBP.Histone deacetylase controls adult stem cell aging by balancing the expression of polycomb genes and jumonji domain containing 3The localization of histone H3K27me3 demethylase Jmjd3 is dynamically regulatedMIR146A inhibits JMJD3 expression and osteogenic differentiation in human mesenchymal stem cells.p53 interaction with JMJD3 results in its nuclear distribution during mouse neural stem cell differentiation.Stage-dependent and locus-specific role of histone demethylase Jumonji D3 (JMJD3) in the embryonic stages of lung development.KDM6 demethylase independent loss of histone H3 lysine 27 trimethylation during early embryonic development.The molecular balancing act of p16(INK4a) in cancer and aging.The histone demethylase Jarid1b (Kdm5b) is a novel component of the Rb pathway and associates with E2f-target genes in MEFs during senescence.MSK1 triggers the expression of the INK4AB/ARF locus in oncogene-induced senescence.Activation of Bmp2-Smad1 signal and its regulation by coordinated alteration of H3K27 trimethylation in Ras-induced senescence.Chromatin and oxygen sensing in the context of JmjC histone demethylasesDNA methylation-mediated repression of miR-941 enhances lysine (K)-specific demethylase 6B expression in hepatoma cells.Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer.Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock.
P2860
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P2860
The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The H3K27me3 demethylase JMJD3 ...... and stress-induced senescence
@ast
The H3K27me3 demethylase JMJD3 ...... and stress-induced senescence
@en
The H3K27me3 demethylase JMJD3 ...... and stress-induced senescence
@nl
type
label
The H3K27me3 demethylase JMJD3 ...... and stress-induced senescence
@ast
The H3K27me3 demethylase JMJD3 ...... and stress-induced senescence
@en
The H3K27me3 demethylase JMJD3 ...... and stress-induced senescence
@nl
prefLabel
The H3K27me3 demethylase JMJD3 ...... and stress-induced senescence
@ast
The H3K27me3 demethylase JMJD3 ...... and stress-induced senescence
@en
The H3K27me3 demethylase JMJD3 ...... and stress-induced senescence
@nl
P2093
P2860
P3181
P356
P1433
P1476
The H3K27me3 demethylase JMJD3 ...... and stress-induced senescence
@en
P2093
Gitte Andersen
Jesper Christensen
Karl Agger
Lise Rudkjaer
Paul A C Cloos
P2860
P304
P3181
P356
10.1101/GAD.510809
P407
P577
2009-05-15T00:00:00Z