A galactosylceramide binding domain is involved in trafficking of CLN3 from Golgi to rafts via recycling endosomes
about
Membrane trafficking and mitochondrial abnormalities precede subunit c deposition in a cerebellar cell model of juvenile neuronal ceroid lipofuscinosisDistinct early molecular responses to mutations causing vLINCL and JNCL presage ATP synthase subunit C accumulation in cerebellar cellsBtn3 is a negative regulator of Btn2-mediated endosomal protein trafficking and prion curing in yeast.Increased expression of lysosomal acid phosphatase in CLN3-defective cells and mouse brain tissueCLN3p impacts galactosylceramide transport, raft morphology, and lipid contentPotential mechanisms for increased HIV-1 transmission across the endocervical epithelium during C. trachomatis infection.Alterations in ROS activity and lysosomal pH account for distinct patterns of macroautophagy in LINCL and JNCL fibroblasts.Ceramide glycosylation catalyzed by glucosylceramide synthase and cancer drug resistance.A novel interaction of CLN3 with nonmuscle myosin-IIB and defects in cell motility of Cln3(-/-) cellsMolecular insights into amyloid regulation by membrane cholesterol and sphingolipids: common mechanisms in neurodegenerative diseasesThe juvenile Batten disease protein, CLN3, and its role in regulating anterograde and retrograde post-Golgi trafficking.The CLN9 protein, a regulator of dihydroceramide synthase.Osmotic stress changes the expression and subcellular localization of the Batten disease protein CLN3.Partial genetic suppression of a loss-of-function mutant of the neuronal ceroid lipofuscinosis-associated protease TPP1 in Dictyostelium discoideum.Unbiased Cell-based Screening in a Neuronal Cell Model of Batten Disease Highlights an Interaction between Ca2+ Homeostasis, Autophagy, and CLN3 Protein Function.Antigen presenting cell abnormalities in the Cln3(-/-) mouse model of juvenile neuronal ceroid lipofuscinosisIsolation of rafts from mouse brain tissue by a detergent-free methodRaft aggregation with specific receptor recruitment is required for microglial phagocytosis of Abeta42.CLN3 loss disturbs membrane microdomain properties and protein transport in brain endothelial cells.Screening for calcium channel modulators in CLN3 siRNA knock down SH-SY5Y neuroblastoma cells reveals a significant decrease of intracellular calcium levels by selected L-type calcium channel blockers.Interactions between the juvenile Batten disease gene, CLN3, and the Notch and JNK signalling pathways.Neuronal ceroid lipofuscinosis: a common pathway?Mutant batten disease protein says "no" to unsaturated fats.Inflammatory, oxidative and lipid perspectives on dementia in HIV-infected patients.Altered Expression of Ganglioside Metabolizing Enzymes Results in GM3 Ganglioside Accumulation in Cerebellar Cells of a Mouse Model of Juvenile Neuronal Ceroid Lipofuscinosis.Flupirtine derivatives as potential treatment for the neuronal ceroid lipofuscinoses
P2860
Q24791822-A6EE4B4E-7E47-4125-B1CF-B11B89F4141CQ27354870-4F0CAA29-75A6-41FE-B6CC-0C5D2B993801Q27938198-3168DE8B-BB40-4877-85F2-23C97978F5C7Q28114924-24BAF478-A765-4396-A5C7-16D603E30058Q28271390-29C8725C-54A3-421F-812C-638DCB89599DQ30413754-FE7C0426-C04D-429E-AD4D-4D1E9790CB6AQ31110961-FABC26F1-0600-4924-AAB2-E8CA3B111B0CQ33733991-8A8A04A2-889B-46BD-B88C-AEEBDE0183C6Q34014206-BB93CFD3-B49B-41DC-B5F3-8BD2EFB0545BQ34098005-D8E93422-0C4E-4A63-B5E8-CDA910D2269FQ34271805-51E4452F-44F7-4F21-877E-0E8E761998DCQ34469580-CAA27148-DF83-40DD-88CD-F6BF0031FE3BQ34805162-80F749C4-32E1-4E41-9B09-57A19E735D78Q35041354-49B0E48F-6E3A-46BC-A17D-F597F7C6A842Q35860759-DFF02B62-FA29-46B6-AEBA-C152B12F3B51Q36986268-66830D14-CCDC-46FD-9C86-44A980A16B53Q37130835-8DBE5072-9082-4276-8E6A-A3D5E0A91C7CQ37172843-2D0FF7E4-D1E6-4D64-B3E5-CBE30E43BB31Q37309514-23B1CD7C-9F7A-4BA3-B10D-9213C8549888Q39646522-5E5778B0-18D3-4E5B-8BB8-927B8615D6F7Q39912954-BA8F115D-00FA-4552-A6E9-1B05C73D6C3DQ40181051-81A775A6-0961-4520-89FA-06D6C94F6E4BQ42123075-C40964DC-B5E1-44C6-96DB-E5A4DA75255AQ45136860-15B012E9-E2C0-4285-8775-AD99588821C7Q51748958-9A3E154D-630E-451F-A040-028BD4E7924AQ58779774-1151EE39-F790-4971-A99B-8EF95A5C6EBE
P2860
A galactosylceramide binding domain is involved in trafficking of CLN3 from Golgi to rafts via recycling endosomes
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
A galactosylceramide binding d ...... rafts via recycling endosomes
@ast
A galactosylceramide binding d ...... rafts via recycling endosomes
@en
A galactosylceramide binding d ...... rafts via recycling endosomes
@en-gb
A galactosylceramide binding d ...... rafts via recycling endosomes
@nl
type
label
A galactosylceramide binding d ...... rafts via recycling endosomes
@ast
A galactosylceramide binding d ...... rafts via recycling endosomes
@en
A galactosylceramide binding d ...... rafts via recycling endosomes
@en-gb
A galactosylceramide binding d ...... rafts via recycling endosomes
@nl
prefLabel
A galactosylceramide binding d ...... rafts via recycling endosomes
@ast
A galactosylceramide binding d ...... rafts via recycling endosomes
@en
A galactosylceramide binding d ...... rafts via recycling endosomes
@en-gb
A galactosylceramide binding d ...... rafts via recycling endosomes
@nl
P2093
P2860
P1433
P1476
A galactosylceramide binding d ...... rafts via recycling endosomes
@en
P2093
Antonius Vandongen
Dixie-Ann Persaud-Sawin
James O McNamara
Rose-Mary N Boustany
Svetlana Rylova
P2860
P304
P356
10.1203/01.PDR.0000136152.54638.95
P407
P577
2004-09-01T00:00:00Z
P6179
1002447145