Genome instability and transcription elongation impairment in human cells depleted of THO/TREX
about
A quantitative telomeric chromatin isolation protocol identifies different telomeric statesThe RNA Splicing Response to DNA DamageThe Clothes Make the mRNA: Past and Present Trends in mRNP FashionThe Caenorhabditis elegans THO complex is required for the mitotic cell cycle and developmentR-loop mediated transcription-associated recombination in trf4Δ mutants reveals new links between RNA surveillance and genome integrity.The Transcription Factor THO Promotes Transcription Initiation and Elongation by RNA Polymerase I.Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes.Defective control of pre-messenger RNA splicing in human diseaseThe role of TREX in gene expression and diseaseRNA Exosome Regulates AID DNA Mutator Activity in the B Cell GenomeThe Thoc1 encoded ribonucleoprotein is a substrate for the NEDD4-1 E3 ubiquitin protein ligaseProcessing of double-R-loops in (CAG)·(CTG) and C9orf72 (GGGGCC)·(GGCCCC) repeats causes instability.Senataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage response.Replication fork stability is essential for the maintenance of centromere integrity in the absence of heterochromatinThe Thoc1 encoded ribonucleoprotein is required for myeloid progenitor cell homeostasis in the adult mouseMechanisms of genome instability induced by RNA-processing defects.A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expressionR-loop formation is a distinctive characteristic of unmethylated human CpG island promoters.Genome-wide profiling of yeast DNA:RNA hybrid prone sites with DRIP-chipThe Thoc1 ribonucleoprotein and prostate cancer progression.Depletion of REF/Aly alters gene expression and reduces RNA polymerase II occupancy.Divergent transcription is associated with promoters of transcriptional regulators.A novel mechanism inducing genome instability in Kaposi's sarcoma-associated herpesvirus infected cells.R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutantsThe Fanconi Anemia Pathway Protects Genome Integrity from R-loops.The Yin and Yang of R-loop biology.Regulated Formation of lncRNA-DNA Hybrids Enables Faster Transcriptional Induction and Environmental Adaptation.Excess of Yra1 RNA-Binding Factor Causes Transcription-Dependent Genome Instability, Replication Impairment and Telomere ShorteningTranscription as a source of genome instability.Methylation-dependent and independent regulatory regions in the Na,K-ATPase alpha4 (Atp1a4) gene may impact its testis-specific expressionThe control of elongation by the yeast Ccr4-not complexSplicing-independent loading of TREX on nascent RNA is required for efficient expression of dual-strand piRNA clusters in Drosophila.Back to the origin: reconsidering replication, transcription, epigenetics, and cell cycle control.The SAGA Deubiquitination Module Promotes DNA Repair and Class Switch Recombination through ATM and DNAPK-Mediated γH2AX Formation.Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I.The THO ribonucleoprotein complex is required for stem cell homeostasis in the adult mouse small intestineGenetic risk factors in two Utah pedigrees at high risk for suicide.Cotranscriptional recruitment of yeast TRAMP complex to intronic sequences promotes optimal pre-mRNA splicing.SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damageSumoylation of the THO complex regulates the biogenesis of a subset of mRNPs.
P2860
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P2860
Genome instability and transcription elongation impairment in human cells depleted of THO/TREX
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Genome instability and transcr ...... man cells depleted of THO/TREX
@ast
Genome instability and transcr ...... man cells depleted of THO/TREX
@en
Genome instability and transcr ...... man cells depleted of THO/TREX
@nl
type
label
Genome instability and transcr ...... man cells depleted of THO/TREX
@ast
Genome instability and transcr ...... man cells depleted of THO/TREX
@en
Genome instability and transcr ...... man cells depleted of THO/TREX
@nl
prefLabel
Genome instability and transcr ...... man cells depleted of THO/TREX
@ast
Genome instability and transcr ...... man cells depleted of THO/TREX
@en
Genome instability and transcr ...... man cells depleted of THO/TREX
@nl
P2093
P2860
P921
P3181
P1433
P1476
Genome instability and transcr ...... man cells depleted of THO/TREX
@en
P2093
Belén Gómez-González
María S Domínguez-Sánchez
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1002386
P407
P577
2011-12-01T00:00:00Z