Processing of double-R-loops in (CAG)·(CTG) and C9orf72 (GGGGCC)·(GGCCCC) repeats causes instability. - Test2 - elhamkhani - TriplyDB

Processing of double-R-loops in (CAG)·(CTG) and C9orf72 (GGGGCC)·(GGCCCC) repeats causes instability.

Processing of double-R-loops in (CAG)·(CTG) and C9orf72 (GGGGCC)·(GGCCCC) repeats causes instability.

http://www.wikidata.org/entity/Q30409374

about

Replication and transcription on a collision course: eukaryotic regulation mechanisms and implications for DNA stability G-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptome DNA Replication Dynamics of the GGGGCC Repeat of the C9orf72 Gene.A C9ORF72 BAC mouse model recapitulates key epigenetic perturbations of ALS/FTD Linking RNA Dysfunction and Neurodegeneration in Amyotrophic Lateral Sclerosis.Repeat instability during DNA repair: Insights from model systems The Repeat Expansion Diseases: The dark side of DNA repair.Emerging role of RNA•DNA hybrids in C9orf72-linked neurodegeneration.Quadruplex formation by both G-rich and C-rich DNA strands of the C9orf72 (GGGGCC)8•(GGCCCC)8 repeat: effect of CpG methylation.Screening for novel hexanucleotide repeat expansions at ALS- and FTD-associated loci.R Loops and Links to Human Disease.Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene.RNA toxicity and foci formation in microsatellite expansion diseases.Close encounters: Moving along bumps, breaks, and bubbles on expanded trinucleotide tracts.RNA Misprocessing in C9orf72-Linked Neurodegeneration.RNA biology of disease-associated microsatellite repeat expansions.Cytosine deamination and base excision repair cause R-loop-induced CAG repeat fragility and instability in Saccharomyces cerevisiae.A Defective mRNA Cleavage and Polyadenylation Complex Facilitates Expansions of Transcribed (GAA)n Repeats Associated with Friedreich's Ataxia Dynamic nucleoplasmic and nucleolar localization of mammalian RNase H1 in response to RNAP I transcriptional R-loops.R-loops: targets for nuclease cleavage and repeat instability.RNA-DNA hybrids promote the expansion of Friedreich's ataxia (GAA)n repeats via break-induced replication.The Chromatin Remodeler Isw1 Prevents CAG Repeat Expansions During Transcription in Saccharomyces cerevisiae.

P2860

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P2860

Processing of double-R-loops in (CAG)·(CTG) and C9orf72 (GGGGCC)·(GGCCCC) repeats causes instability.

http://www.wikidata.org/entity/Q30409374

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Processing of double-R-loops i ...... C) repeats causes instability.

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Processing of double-R-loops i ...... C) repeats causes instability.

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Processing of double-R-loops i ...... C) repeats causes instability.

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Processing of double-R-loops i ...... C) repeats causes instability.

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Processing of double-R-loops i ...... C) repeats causes instability.

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Processing of double-R-loops i ...... C) repeats causes instability.

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P1433

Nucleic Acids Research

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Processing of double-R-loops i ...... C) repeats causes instability.

@en

P2093

Christopher E Pearson

http://www.w3.org/2001/XMLSchema#string

Gagan B Panigrahi

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Jaimie M Geist

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Kaalak Reddy

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Monika H M Schmidt

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Neha P Thakkar

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Yuh-Hwa Wang

http://www.w3.org/2001/XMLSchema#string

P2860

Genome instability and transcription elongation impairment in human cells depleted of THO/TREX

Transcription promotes contraction of CAG repeat tracts in human cells

Structure of human RNase H1 complexed with an RNA/DNA hybrid: insight into HIV reverse transcription

Isolated short CTG/CAG DNA slip-outs are repaired efficiently by hMutSbeta, but clustered slip-outs are poorly repaired.

Diverse effects of individual mismatch repair components on transcription-induced CAG repeat instability in human cells.

Convergent transcription through a long CAG tract destabilizes repeats and induces apoptosis

R loops stimulate genetic instability of CTG.CAG repeats.

Fidelity of a human cell DNA replication complex.

C9orf72 nucleotide repeat structures initiate molecular cascades of disease.

R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells.

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10473-10487

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10.1093/NAR/GKU658

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16

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42

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2014-08-21T00:00:00Z

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264986330

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25147206

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4176329

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