The human kinesin Kif18A is a motile microtubule depolymerase essential for chromosome congression
about
Proteomic detection of cancer in asbestosis patients using SELDI-TOF discovered serum protein biomarkersCLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelityMechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complexDDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movementA high-coverage genome sequence from an archaic Denisovan individualThe kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignmentPreclinical Childhood Sarcoma Models: Drug Efficacy Biomarker Identification and ValidationThe dynamics of plus end polarization and microtubule assembly during Xenopus cortical rotationS. pombe kinesins-8 promote both nucleation and catastrophe of microtubulesA non-motor microtubule binding site is essential for the high processivity and mitotic function of kinesin-8 Kif18ANuSAP governs chromosome oscillation by facilitating the Kid-generated polar ejection forceInsight into the molecular mechanism of the multitasking kinesin-8 motorKinesin Kip2 enhances microtubule growth in vitro through length-dependent feedback on polymerization and catastrophe.The kinesin-8 Kip3 scales anaphase spindle length by suppression of midzone microtubule polymerization.Chromosome congression by Kinesin-5 motor-mediated disassembly of longer kinetochore microtubules.Microtubule-sliding activity of a kinesin-8 promotes spindle assembly and spindle-length control.Regulation of Microtubule Growth and Catastrophe: Unifying Theory and ExperimentKinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerasesMitotic spindle disassembly occurs via distinct subprocesses driven by the anaphase-promoting complex, Aurora B kinase, and kinesin-8Kinesin-8 from fission yeast: a heterodimeric, plus-end-directed motor that can couple microtubule depolymerization to cargo movementForce- and kinesin-8-dependent effects in the spatial regulation of fission yeast microtubule dynamicsNcd motor binding and transport in the spindle.Coupling between microtubule sliding, plus-end growth and spindle length revealed by kinesin-8 depletionKif18B interacts with EB1 and controls astral microtubule length during mitosis.A tethering mechanism controls the processivity and kinetochore-microtubule plus-end enrichment of the kinesin-8 Kif18A.The coupling between sister kinetochore directional instability and oscillations in centromere stretch in metaphase PtK1 cells.Molecular crowding creates traffic jams of kinesin motors on microtubulesHuman chromokinesins promote chromosome congression and spindle microtubule dynamics during mitosisSpatial control of microtubule length and lifetime by opposing stabilizing and destabilizing functions of Kinesin-8Kinesin-12 Kif15 targets kinetochore fibers through an intrinsic two-step mechanismSumoylation of Kif18A plays a role in regulating mitotic progressionProbing microtubule polymerisation state at single kinetochores during metaphase chromosome motionSpatial regulation of astral microtubule dynamics by Kif18B in PtK cells.Kinesin-8 effects on mitotic microtubule dynamics contribute to spindle function in fission yeast.BTB-1: a small molecule inhibitor of the mitotic motor protein Kif18A.MCAK is present at centromeres, midspindle and chiasmata and involved in silencing of the spindle assembly checkpoint in mammalian oocytes.Xenopus laevis Kif18A is a highly processive kinesin required for meiotic spindle integrityHow kinesin motor proteins drive mitotic spindle function: Lessons from molecular assays.The kinetochoreAutomatic quantification of microtubule dynamics enables RNAi-screening of new mitotic spindle regulators.
P2860
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P2860
The human kinesin Kif18A is a motile microtubule depolymerase essential for chromosome congression
description
2007 nî lūn-bûn
@nan
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The human kinesin Kif18A is a ...... ial for chromosome congression
@ast
The human kinesin Kif18A is a ...... ial for chromosome congression
@en
The human kinesin Kif18A is a ...... ial for chromosome congression
@en-gb
The human kinesin Kif18A is a ...... ial for chromosome congression
@nl
type
label
The human kinesin Kif18A is a ...... ial for chromosome congression
@ast
The human kinesin Kif18A is a ...... ial for chromosome congression
@en
The human kinesin Kif18A is a ...... ial for chromosome congression
@en-gb
The human kinesin Kif18A is a ...... ial for chromosome congression
@nl
prefLabel
The human kinesin Kif18A is a ...... ial for chromosome congression
@ast
The human kinesin Kif18A is a ...... ial for chromosome congression
@en
The human kinesin Kif18A is a ...... ial for chromosome congression
@en-gb
The human kinesin Kif18A is a ...... ial for chromosome congression
@nl
P2093
P921
P3181
P1433
P1476
The human kinesin Kif18A is a ...... ial for chromosome congression
@en
P2093
Guenther Woehlke
Jenny Bormann
Monika I Mayr
Sarah Adio
Tamara Grüner
Thomas U Mayer
P304
P3181
P356
10.1016/J.CUB.2007.02.036
P407
P577
2007-03-08T00:00:00Z