CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity
about
The astrin-kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignmentChromosomal instability and cancer: a complex relationship with therapeutic potentialRegulation of kinetochore-microtubule attachments through homeostatic control during mitosisPutative biomarkers and targets of estrogen receptor negative human breast cancerReconstituting the kinetochore–microtubule interface: what, why, and howMolecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and AstrinLateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAKCDK-1 Inhibition in G2 Stabilizes Kinetochore-Microtubules in the following MitosisNsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase BMultiple cancer testis antigens function to support tumor cell mitotic fidelity.Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic SpindleKif18B interacts with EB1 and controls astral microtubule length during mitosis.The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle.Kinetochore-microtubule stability governs the metaphase requirement for Eg5.A mitotic SKAP isoform regulates spindle positioning at astral microtubule plus ends.Next-generation transcriptome sequencing of the premenopausal breast epithelium using specimens from a normal human breast tissue bank.A TOGL domain specifically targets yeast CLASP to kinetochores to stabilize kinetochore microtubules.Aurora B kinase controls the targeting of the Astrin-SKAP complex to bioriented kinetochores.Sensing centromere tension: Aurora B and the regulation of kinetochore function.Chromosomal instability substantiates poor prognosis in patients with diffuse large B-cell lymphoma.Cdk1 phosphorylation of the kinetochore protein Nsk1 prevents error-prone chromosome segregation.Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1.Mitotic Protein CSPP1 Interacts with CENP-H Protein to Coordinate Accurate Chromosome Oscillation in MitosisCdk1 and Plk1 mediate a CLASP2 phospho-switch that stabilizes kinetochore-microtubule attachmentsMitotic regulator SKAP forms a link between kinetochore core complex KMN and dynamic spindle microtubules.Unattached kinetochores rather than intrakinetochore tension arrest mitosis in taxol-treated cellsMaking an effective switch at the kinetochore by phosphorylation and dephosphorylation.Expression of dynein, cytoplasmic 2, heavy chain 1 (DHC2) associated with glioblastoma cell resistance to temozolomide.Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation.Array-CGH diagnosis in ovarian failure: identification of new molecular actors for ovarian physiology.Mechanisms of Chromosome Congression during Mitosis.Prevention and correction mechanisms behind anaphase synchrony: implications for the genesis of aneuploidy.Regulation of microtubule dynamics by TOG-domain proteins XMAP215/Dis1 and CLASP.Shaping microtubules into diverse patterns: molecular connections for setting up both ends.Kinetochores and disease: keeping microtubule dynamics in check!Regulatory mechanisms of kinetochore-microtubule interaction in mitosis.Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint.The molecular basis for kinesin functional specificity during mitosis.Linked in: formation and regulation of microtubule attachments during chromosome segregation.
P2860
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P2860
CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity
description
2010 nî lūn-bûn
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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
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2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
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2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
CLASP1, astrin and Kif2b form ...... totic progression and fidelity
@ast
CLASP1, astrin and Kif2b form ...... totic progression and fidelity
@en
CLASP1, astrin and Kif2b form ...... totic progression and fidelity
@en-gb
CLASP1, astrin and Kif2b form ...... totic progression and fidelity
@nl
type
label
CLASP1, astrin and Kif2b form ...... totic progression and fidelity
@ast
CLASP1, astrin and Kif2b form ...... totic progression and fidelity
@en
CLASP1, astrin and Kif2b form ...... totic progression and fidelity
@en-gb
CLASP1, astrin and Kif2b form ...... totic progression and fidelity
@nl
prefLabel
CLASP1, astrin and Kif2b form ...... totic progression and fidelity
@ast
CLASP1, astrin and Kif2b form ...... totic progression and fidelity
@en
CLASP1, astrin and Kif2b form ...... totic progression and fidelity
@en-gb
CLASP1, astrin and Kif2b form ...... totic progression and fidelity
@nl
P2093
P2860
P3181
P356
P1433
P1476
CLASP1, astrin and Kif2b form ...... totic progression and fidelity
@en
P2093
Amity L Manning
Clara Correia-Melo
Duane A Compton
Helder Maiato
Samuel F Bakhoum
Stefano Maffini
P2860
P304
P3181
P356
10.1038/EMBOJ.2010.230
P407
P577
2010-10-20T00:00:00Z