Five dysfunctional telomeres predict onset of senescence in human cells
about
The telomere syndromesTranscription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) GeneEvaluating biomarkers to model cancer risk post cosmic ray exposureMarkers of cellular senescence. Telomere shortening as a marker of cellular senescenceTelomere biology: Rationale for diagnostics and therapeutics in cancerLength-dependent processing of telomeres in the absence of telomerase.Short Telomeres in Key Tissues Initiate Local and Systemic Aging in ZebrafishCellular senescence drives age-dependent hepatic steatosis.Withaferin-A kills cancer cells with and without telomerase: chemical, computational and experimental evidences.Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis.The luminal progenitor compartment of the normal human mammary gland constitutes a unique site of telomere dysfunction.Recombinogenic telomeres in diploid Sorex granarius (Soricidae, Eulipotyphla) fibroblast cells.Role of arterial telomere dysfunction in hypertension: relative contributions of telomere shortening and telomere uncapping.Telomere maintenance mechanisms in cancer: clinical implicationsUp-regulation of leucocytes genes implicated in telomere dysfunction and cellular senescence correlates with depression and anxiety severity scores.A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds.Functional significance of point mutations in stress chaperone mortalin and their relevance to Parkinson disease.A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase.NQO1 Stabilizes p53 in Response to Oncogene-Induced Senescence.Multiple Mechanisms Contribute to the Cell Growth Defects Imparted by Human Telomerase Insertion in Fingers Domain Mutations Associated with Premature Aging Diseases.Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions.ATRX represses alternative lengthening of telomeres.Mechanisms of telomere loss and their consequences for chromosome instability.DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease.Dysfunctional telomeres in primary cells from Fanconi anemia FANCD2 patientsA three-state model of telomere control over human proliferative boundaries.CRISPR-CAS9 D10A nickase target-specific fluorescent labeling of double strand DNA for whole genome mapping and structural variation analysis.Complex interactions between the DNA-damage response and mammalian telomeres.Aberrant reduction of telomere repetitive sequences in plasma cell-free DNA for early breast cancer detection.Association of telomere instability with senescence of porcine cellsChromatin structure in telomere dynamicsSaccharomyces cerevisiae as a Model to Study Replicative Senescence Triggered by Telomere Shortening.Visualization of Telomere Integrity and Function In Vitro and In Vivo Using Immunofluorescence Techniques.The Deadbeat Paternal Effect of Uncapped Sperm Telomeres on Cell Cycle Progression and Chromosome Behavior in Drosophila melanogaster.Age-related telomere uncapping is associated with cellular senescence and inflammation independent of telomere shortening in human arteriesMutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects.TRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End ProtectionStop pulling my strings - what telomeres taught us about the DNA damage response.Regulation of telomere addition at DNA double-strand breaks.Telomeres, oxidative stress and inflammatory factors: partners in cellular senescence?
P2860
Q24632444-7F504FB6-9CF3-47C3-9844-313533F3DF39Q26739925-B52E9A7E-95EB-4147-927C-CB728ECA2150Q26747120-0638899B-5400-4F9D-BBA1-8A6D619E78B4Q26775163-2F64A339-EEEB-486E-8164-EF86DB142CD2Q26796323-168F01F4-DCA7-43DD-81B4-53DFC5016AEAQ27940217-4DF0D81A-A686-49D7-98B7-FB7D50D4BD83Q28272305-5E72F720-531B-4C14-999C-1E6CFD328BF2Q33810220-A6EFF130-5FFA-4DF9-B8D5-F5429A2B3B4AQ33815938-B17A717F-B689-41F7-AAEB-AD19FD55DB1AQ33990112-57CABAC2-4937-4ACA-A423-BCC05C562CB4Q34038272-D1D8F90A-5BD7-4DFD-B3B3-2F94B1F5EA30Q34056440-41188071-C015-47CB-940D-4B2059CA53EFQ34344433-9F56D7E4-4E87-45AE-8516-7504F846A077Q34426966-88F1C0C9-8AAA-4CF7-8265-501092DADC2AQ34490369-9B105038-EF78-47B1-89E2-C8D64668D1F5Q35089022-2FD606F4-92F0-4BA1-8CB9-B64C298D2269Q35221600-E6529F0D-C115-4E14-8E43-CBADE6572CAFQ35656649-4C5BF2F9-8FE2-45CF-807A-836DDA289738Q35739627-3C26DC74-B56E-4B9C-9C77-EB8E9C397305Q35926634-DDC19621-215E-4B4C-B50A-E996C0553F99Q36090294-D34125E5-C191-4BA8-8324-A86DE10D5DB7Q36140856-646DEE01-26C1-4C77-AD94-1C0EB1526969Q36296137-D253B6E3-07A2-4CFC-B970-9E2B344479D3Q36297787-407CF502-7AF0-4DE5-B2F2-DA64A9C03277Q36437240-5570DA60-ACB8-4E40-BD93-7DD31E51D001Q36494808-270370F0-FE48-4817-ABA2-FE431F9A36A9Q36532719-5023C6E7-F45D-43FB-BD5D-94E4504C92DCQ36539673-DD3DC6D3-48C7-4C84-A82F-1D511DD15297Q36557431-F2E5571E-7BFD-4B4A-A7B0-D314EC8A26DCQ36585066-3F5355F4-56C4-4B4A-B055-7B4BB6E227A4Q36662986-8C02A29B-5C0C-4F51-8E01-80F0736610BCQ36795512-B7B6D811-E9C3-41A9-A40C-8EF5040047C1Q36887486-20E98040-47B4-4DF5-B24D-34D0535BD556Q36976883-71133AD4-CA63-48BB-B18C-01F35B0E8A5EQ37054523-D8F41560-C776-4FCA-BE5F-21087A359348Q37178997-7A8F4516-6845-482B-8BB7-A3F92997DCBEQ37210618-48E9619A-4550-4A1A-B66D-29C9B6F228BFQ37742751-1541C966-B314-42CB-BF9A-3C9E225383FCQ38090496-A9C7D5CD-E461-4851-AE3C-677ED17A481CQ38182713-2BFFE406-D1E7-49D7-9F2B-6EF999FA2FFD
P2860
Five dysfunctional telomeres predict onset of senescence in human cells
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Five dysfunctional telomeres predict onset of senescence in human cells
@ast
Five dysfunctional telomeres predict onset of senescence in human cells
@en
Five dysfunctional telomeres predict onset of senescence in human cells
@en-gb
Five dysfunctional telomeres predict onset of senescence in human cells
@nl
type
label
Five dysfunctional telomeres predict onset of senescence in human cells
@ast
Five dysfunctional telomeres predict onset of senescence in human cells
@en
Five dysfunctional telomeres predict onset of senescence in human cells
@en-gb
Five dysfunctional telomeres predict onset of senescence in human cells
@nl
prefLabel
Five dysfunctional telomeres predict onset of senescence in human cells
@ast
Five dysfunctional telomeres predict onset of senescence in human cells
@en
Five dysfunctional telomeres predict onset of senescence in human cells
@en-gb
Five dysfunctional telomeres predict onset of senescence in human cells
@nl
P2093
P2860
P3181
P356
P1433
P1476
Five dysfunctional telomeres predict onset of senescence in human cells
@en
P2093
Anthony J Cesare
Axel A Neumann
Lily I Huschtscha
Zeenia Kaul
P2860
P3181
P356
10.1038/EMBOR.2011.227
P407
P577
2012-01-01T00:00:00Z