about
Diminished telomeric 3' overhangs are associated with telomere dysfunction in Hoyeraal-Hreidarsson syndromeTelomeres in Cancer TherapyKu is associated with the telomere in mammalsTIN2, a new regulator of telomere length in human cellsRole for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeresColocalization, physical, and functional interaction between Werner and Bloom syndrome proteinsTargeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2Rap1 affects the length and heterogeneity of human telomeresFive dysfunctional telomeres predict onset of senescence in human cellsTelomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicasesTelosome, a mammalian telomere-associated complex formed by multiple telomeric proteinsGenome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cellsThe human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activityWRN controls formation of extrachromosomal telomeric circles and is required for TRF2DeltaB-mediated telomere shorteningPOT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substratesIn vivo stoichiometry of shelterin componentsTelomere-bound TRF1 and TRF2 stall the replication fork at telomeric repeatsTRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwindingTelomere protection by mammalian Pot1 requires interaction with Tpp1POT1 association with TRF2 regulates telomere lengthConstitutional mutations in RTEL1 cause severe dyskeratosis congenitaCharacterization of the DNA binding specificity of Shelterin complexesHow the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high-resolution crystal structuresTelomere dysfunction and cell survival: roles for distinct TIN2-containing complexesPOT1 and TRF2 cooperate to maintain telomeric integrityhnRNP A2, a potential ssDNA/RNA molecular adapter at the telomereHuman telomerase and its regulationMammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres.Human Pot1 (protection of telomeres) protein: cytolocalization, gene structure, and alternative splicingFormation of extrachromosomal circles from telomeric DNA in Xenopus laevis.Cell cycle-dependent recruitment of telomerase RNA and Cajal bodies to human telomeresTelomeres, telomerase, and tumorigenesis--a reviewControl of human telomere length by TRF1 and TRF2Rescue of an hTERT mutant defective in telomere elongation by fusion with hPot1Finding the end: recruitment of telomerase to telomeresFunctional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elongationHuman RECQ helicases: roles in DNA metabolism, mutagenesis and cancer biologyRoles of Werner syndrome protein in protection of genome integrityModel of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromesRoles of RECQ helicases in recombination based DNA repair, genomic stability and aging
P2860
Q21090064-73B511A2-51BB-4659-8EDB-B8C930FFA6D9Q21146989-55A1A3BB-3F7A-4EB8-9431-AA41B76D6F59Q22010717-FB894817-2B8F-4C46-BA83-5DB62308BA7AQ22010863-91AB716C-9C81-4C15-BA80-F97AF4C09C53Q24291989-0833D501-17E4-4C1C-9FCC-0211F796AE5BQ24292733-50541B88-C7A2-4BD9-BE5F-13867DB49C89Q24295044-4D89F298-9155-43B0-B64E-593AD22090A5Q24298023-7799DF31-CE9D-43E4-B80E-0D6C0EF80382Q24299538-3D90B024-67C9-458F-A62F-709D08F3020BQ24304488-E38E52EC-FF1F-4D42-8AFC-4B27C7754408Q24304989-8088EE69-CAD4-4802-9B2E-2E4B76FCBEC2Q24305322-32BA4248-B1CF-488C-8E9A-2475E1BE3D86Q24306780-D03BF4EF-2F7D-4B5D-97FC-7457EF0DC813Q24307499-7ED74211-9E3A-4015-955E-01DBC385D5B1Q24308828-23FE1F30-A3D5-49E8-A9FE-6DECBF4E9499Q24312021-7090CF1A-AA28-48AB-805B-2BD07145711FQ24315056-330E64C6-6328-4646-B5D3-617528FC7264Q24316035-15DB9ECB-9D8E-4885-A7BE-A8FA30C7D6C5Q24319841-24C14866-9A5B-4E1F-A6B4-0E24AF6A2233Q24320254-C06F6028-D8DC-4C80-A8E3-6AB00B048129Q24321641-F300A451-BF46-410C-90F0-B62FDAED59D5Q24323345-416C7C50-68DE-4A9E-8C92-9D3876CFAC10Q24323494-F716A7D3-8477-4EB1-90A0-152EA1E3F2BAQ24336203-EA8EFE0D-0996-418C-8B32-E5DFFDA9C5D9Q24338505-39BB8AA4-4942-460B-ADAC-112EA22B239EQ24338517-7769F8A6-F910-4253-BBEC-B5BED0CC64EEQ24533247-BA44CCAD-A307-4220-B361-E95003D0F5E0Q24536297-877E3904-AD5A-43B1-B6BD-0DA32DD58946Q24538105-31197360-21E0-4065-B92A-1167C63F5117Q24538889-003DC1E2-F926-46C4-9E98-078BD6588DF5Q24540232-9CE09BE1-90D8-4FA5-B33F-1CCAED484194Q24548220-3F18B550-44DD-4838-AF4F-2F0A1B9F5CC1Q24554302-EF81071B-00FB-419B-9E62-FD8AFE14ADD8Q24603295-0C70E7DA-D6CD-44A5-AFE3-77D721429E16Q24606549-01AD0CBC-8597-445F-9085-0ECD678B4829Q24607672-5EA6C6B3-12D3-41C4-A2E1-31F03CC9A02DQ24620195-E4078C0C-F073-4488-9F21-25A93CDE41FBQ24643050-0E50067D-A210-4CAE-B31C-0A05DEBFD08BQ24644033-38353D6A-0780-49F0-9CB5-E7B5CDA603E2Q24646853-DAC86EDC-C7A4-4E7E-90DE-032333D77751
P2860
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Mammalian telomeres end in a large duplex loop
@ast
Mammalian telomeres end in a large duplex loop
@de
Mammalian telomeres end in a large duplex loop
@en
Mammalian telomeres end in a large duplex loop
@en-gb
Mammalian telomeres end in a large duplex loop
@fr
Mammalian telomeres end in a large duplex loop
@nl
type
label
Mammalian telomeres end in a large duplex loop
@ast
Mammalian telomeres end in a large duplex loop
@de
Mammalian telomeres end in a large duplex loop
@en
Mammalian telomeres end in a large duplex loop
@en-gb
Mammalian telomeres end in a large duplex loop
@fr
Mammalian telomeres end in a large duplex loop
@nl
altLabel
Mammalian Telomeres End in a Large Duplex Loop
@en
prefLabel
Mammalian telomeres end in a large duplex loop
@ast
Mammalian telomeres end in a large duplex loop
@de
Mammalian telomeres end in a large duplex loop
@en
Mammalian telomeres end in a large duplex loop
@en-gb
Mammalian telomeres end in a large duplex loop
@fr
Mammalian telomeres end in a large duplex loop
@nl
P2093
P921
P3181
P1433
P1476
Mammalian telomeres end in a large duplex loop
@en
P2093
J D Griffith
R M Stansel
S Rosenfield
P304
P3181
P356
10.1016/S0092-8674(00)80760-6
P407
P577
1999-05-14T00:00:00Z