NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia
about
An integrative computational systems biology approach identifies differentially regulated dynamic transcriptome signatures which drive the initiation of human T helper cell differentiationMicroRNA regulation of T-lymphocyte immunity: modulation of molecular networks responsible for T-cell activation, differentiation, and developmentMiR-146b negatively regulates migration and delays progression of T-cell acute lymphoblastic leukemiaTranscriptional activation of prostate specific homeobox gene NKX3-1 in subsets of T-cell lymphoblastic leukemia (T-ALL).Interleukin-18 produced by bone marrow-derived stromal cells supports T-cell acute leukaemia progressionEctopic expression of homeobox gene NKX2-1 in diffuse large B-cell lymphoma is mediated by aberrant chromatin modifications.SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cellsGATA Transcription Factors and Cancer.Structural analysis of microRNA-target interaction by sequential seed mutagenesis and stem-loop 3' RACE.Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis.Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia.High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells.NKL homeobox gene activities in hematopoietic stem cells, T-cell development and T-cell leukemia.TRIM33 switches off Ifnb1 gene transcription during the late phase of macrophage activation.Dynamic interaction between TAL1 oncoprotein and LSD1 regulates TAL1 function in hematopoiesis and leukemogenesis.UTX inhibition as selective epigenetic therapy against TAL1-driven T-cell acute lymphoblastic leukemiaIntracellular Signaling Pathways Involved in Childhood Acute Lymphoblastic Leukemia; Molecular TargetsThe TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemiaMYCN is a novel oncogenic target in pediatric T-cell acute lymphoblastic leukemia.Loss of GATA3 in bladder cancer promotes cell migration and invasion.NKL homeobox genes in leukemia.Concise review: Blood relatives: formation and regulation of hematopoietic stem cells by the basic helix-loop-helix transcription factors stem cell leukemia and lymphoblastic leukemia-derived sequence 1.LIM-domain-only proteins in cancer.Repressed BMP signaling reactivates NKL homeobox gene MSX1 in a T-ALL subset.Stem Cell Leukemia: how a TALented actor can go awry on the hematopoietic stage.Activation of Paired-homeobox gene PITX1 by del(5)(q31) in T-cell acute lymphoblastic leukemia.ARID5B as a critical downstream target of the TAL1 complex that activates the oncogenic transcriptional program and promotes T-cell leukemogenesis.Nkx2-3-A Slippery Slope From Development Through Inflammation Toward Hematopoietic Malignancies.Rat stem-cell leukemia gene expression increased during testis maturation.TCRα rearrangements identify a subgroup of NKL-deregulated adult T-ALLs associated with favorable outcome.Aberrant activity of NKL homeobox gene NKX3-2 in a T-ALL subset.NKX2-2 Suppresses Osteosarcoma Metastasis and Proliferation by Downregulating Multiple Target Genes
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P248
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P2860
NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
NKX3.1 is a direct TAL1 target ...... l acute lymphoblastic leukemia
@ast
NKX3.1 is a direct TAL1 target ...... l acute lymphoblastic leukemia
@en
NKX3.1 is a direct TAL1 target ...... l acute lymphoblastic leukemia
@en-gb
NKX3.1 is a direct TAL1 target ...... l acute lymphoblastic leukemia
@nl
type
label
NKX3.1 is a direct TAL1 target ...... l acute lymphoblastic leukemia
@ast
NKX3.1 is a direct TAL1 target ...... l acute lymphoblastic leukemia
@en
NKX3.1 is a direct TAL1 target ...... l acute lymphoblastic leukemia
@en-gb
NKX3.1 is a direct TAL1 target ...... l acute lymphoblastic leukemia
@nl
prefLabel
NKX3.1 is a direct TAL1 target ...... l acute lymphoblastic leukemia
@ast
NKX3.1 is a direct TAL1 target ...... l acute lymphoblastic leukemia
@en
NKX3.1 is a direct TAL1 target ...... l acute lymphoblastic leukemia
@en-gb
NKX3.1 is a direct TAL1 target ...... l acute lymphoblastic leukemia
@nl
P2093
P2860
P921
P3181
P356
P1476
NKX3.1 is a direct TAL1 target ...... l acute lymphoblastic leukemia
@en
P2093
André Baruchel
Bastien Gerby
Delphine Gérard
Federica Ferri
Florence Armstrong
Françoise Pflumio
Jean-Michel Cayuela
Nathalie Gault
Nicolas Goardon
Paola Ballerini
P2860
P304
P3181
P356
10.1084/JEM.20100745
P407
P577
2010-09-27T00:00:00Z