The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins
about
Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105Potentiation of GATA-2 activity through interactions with the promyelocytic leukemia protein (PML) and the t(15;17)-generated PML-retinoic acid receptor alpha oncoproteinThe LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activityA critical role for the transcription factor Scl in platelet production during stress thrombopoiesisTargets of the Tal1 transcription factor in erythrocytes: E2 ubiquitin conjugase regulation by Tal1Human Bex2 interacts with LMO2 and regulates the transcriptional activity of a novel DNA-binding complexNKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemiaGATA-1 forms distinct activating and repressive complexes in erythroid cellsCCAR1/CoCoA pair-mediated recruitment of the Mediator defines a novel pathway for GATA1 functionMEF2-dependent recruitment of the HAND1 transcription factor results in synergistic activation of target promotersLMO4 controls the balance between excitatory and inhibitory spinal V2 interneuronsThe LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiationAjuba functions as a histone deacetylase-dependent co-repressor for autoregulation of the growth factor-independent-1 transcription factorInteraction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signalingLSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesisDifferential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineagesIdentification of a WD40 repeat-containing isoform of PHIP as a novel regulator of beta-cell growth and survivalRUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory elementTIF1gamma controls erythroid cell fate by regulating transcription elongationA family of LIM-only transcriptional coactivators: tissue-specific expression and selective activation of CREB and CREMTAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factorGATA-1 mediates auto-regulation of Gfi-1B transcription in K562 cellsSsdp proteins interact with the LIM-domain-binding protein Ldb1 to regulate developmentETO2 coordinates cellular proliferation and differentiation during erythropoiesisLPP, an actin cytoskeleton protein related to zyxin, harbors a nuclear export signal and transcriptional activation capacityA pentamer transcriptional complex including tal-1 and retinoblastoma protein downmodulates c-kit expression in normal erythroblastsHelix-loop-helix proteins: regulators of transcription in eucaryotic organismsChip, a widely expressed chromosomal protein required for segmentation and activity of a remote wing margin enhancer in DrosophilaMicroRNA 223-dependent expression of LMO2 regulates normal erythropoiesisIdentification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesisBinding of serum response factor to cystic fibrosis transmembrane conductance regulator CArG-like elements, as a new potential CFTR transcriptional regulation pathway.Genetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell FunctionMaster regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignanciesFetal globin gene repressors as drug targets for molecular therapies to treat the β-globinopathiesA novel TGFβ modulator that uncouples R-Smad/I-Smad-mediated negative feedback from R-Smad/ligand-driven positive feedbackBmp4 is essential for the formation of the vestibular apparatus that detects angular head movementsTumour prevention by a single antibody domain targeting the interaction of signal transduction proteins with RASStructural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1Solution structure of a tethered Lmo2LIM2/Ldb1LIDcomplex
P2860
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P2860
The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins
@ast
The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins
@en
The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins
@en-gb
The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins
@nl
type
label
The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins
@ast
The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins
@en
The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins
@en-gb
The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins
@nl
prefLabel
The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins
@ast
The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins
@en
The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins
@en-gb
The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins
@nl
P2093
P2860
P3181
P356
P1433
P1476
The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins
@en
P2093
P2860
P304
P3181
P356
10.1093/EMBOJ/16.11.3145
P407
P577
1997-06-01T00:00:00Z