The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins - Test2 - elhamkhani - TriplyDB

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

http://www.wikidata.org/entity/Q24532225

about

Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105 Potentiation of GATA-2 activity through interactions with the promyelocytic leukemia protein (PML) and the t(15;17)-generated PML-retinoic acid receptor alpha oncoprotein The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis Targets of the Tal1 transcription factor in erythrocytes: E2 ubiquitin conjugase regulation by Tal1 Human Bex2 interacts with LMO2 and regulates the transcriptional activity of a novel DNA-binding complex NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia GATA-1 forms distinct activating and repressive complexes in erythroid cells CCAR1/CoCoA pair-mediated recruitment of the Mediator defines a novel pathway for GATA1 function MEF2-dependent recruitment of the HAND1 transcription factor results in synergistic activation of target promoters LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation Ajuba functions as a histone deacetylase-dependent co-repressor for autoregulation of the growth factor-independent-1 transcription factor Interaction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signaling LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages Identification of a WD40 repeat-containing isoform of PHIP as a novel regulator of beta-cell growth and survival RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory element TIF1gamma controls erythroid cell fate by regulating transcription elongation A family of LIM-only transcriptional coactivators: tissue-specific expression and selective activation of CREB and CREM TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3 mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factor GATA-1 mediates auto-regulation of Gfi-1B transcription in K562 cells Ssdp proteins interact with the LIM-domain-binding protein Ldb1 to regulate development ETO2 coordinates cellular proliferation and differentiation during erythropoiesis LPP, an actin cytoskeleton protein related to zyxin, harbors a nuclear export signal and transcriptional activation capacity A pentamer transcriptional complex including tal-1 and retinoblastoma protein downmodulates c-kit expression in normal erythroblasts Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms Chip, a widely expressed chromosomal protein required for segmentation and activity of a remote wing margin enhancer in Drosophila MicroRNA 223-dependent expression of LMO2 regulates normal erythropoiesis Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis Binding of serum response factor to cystic fibrosis transmembrane conductance regulator CArG-like elements, as a new potential CFTR transcriptional regulation pathway.Genetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell Function Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies Fetal globin gene repressors as drug targets for molecular therapies to treat the β-globinopathies A novel TGFβ modulator that uncouples R-Smad/I-Smad-mediated negative feedback from R-Smad/ligand-driven positive feedback Bmp4 is essential for the formation of the vestibular apparatus that detects angular head movements Tumour prevention by a single antibody domain targeting the interaction of signal transduction proteins with RAS Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1 Solution structure of a tethered Lmo2LIM2/Ldb1LIDcomplex

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P2860

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

http://www.wikidata.org/entity/Q24532225

description

1997 nî lūn-bûn

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1997 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1997 թվականի հունիսին հրատարակված գիտական հոդված

@hy

1997年の論文

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1997年学术文章

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1997年学术文章

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1997年学术文章

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1997年学术文章

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1997年学术文章

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1997年學術文章

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name

The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins

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The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins

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The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins

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The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins

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The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins

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The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins

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The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins

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The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins

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The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins

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The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins

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The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins

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The EMBO Journal

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The LIM-only protein Lmo2 is a ...... , GATA-1 and Ldb1/NLI proteins

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Agulnick AD

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Forster A

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Grütz GG

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Osada H

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Wadman IA

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Westphal H

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P2860

TTG-2, a new gene encoding a cysteine-rich protein with the LIM motif, is overexpressed in acute T-cell leukaemia with the t(11;14)(p13;q11)

The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13

The LIM/double zinc-finger motif functions as a protein dimerization domain

Cyclic amplification and selection of targets for multicomponent complexes: myogenin interacts with factors recognizing binding sites for basic helix-loop-helix, nuclear factor 1, myocyte-specific enhancer-binding factor 2, and COMP1 factor

Formation of in vivo complexes between the TAL1 and E2A polypeptides of leukemic T cells

The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells

The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif

Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development

Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

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3145-3157

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scholarly article

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2818736

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10.1093/EMBOJ/16.11.3145

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P433

11

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16

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Terence Rabbitts

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1997-06-01T00:00:00Z

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14004134

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9214632

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1169933

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