Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C
about
Vertebrate nonmuscle myosin II isoforms rescue small interfering RNA-induced defects in COS-7 cell cytokinesisCharacterization of three full-length human nonmuscle myosin II paralogsIdentification of the surfactant protein A receptor 210 as the unconventional myosin 18A.Myosins as fundamental components during tumorigenesis: diverse and indispensableNon-muscle myosin II in disease: mechanisms and therapeutic opportunitiesNonmuscle myosin-2: mix and matchCrystal structure of the rigor-like human non-muscle myosin-2 motor domainThe B2 alternatively spliced isoform of nonmuscle myosin II-B lacks actin-activated MgATPase activity and in vitro motilityNon-muscle myosin II takes centre stage in cell adhesion and migrationNonmuscle myosin II isoform and domain specificity during early mouse developmentAblation of nonmuscle myosin II-B and II-C reveals a role for nonmuscle myosin II in cardiac myocyte karyokinesisFunction of the neuron-specific alternatively spliced isoforms of nonmuscle myosin II-B during mouse brain development.Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner.Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front-back polarity in migrating cellsMyosin II directly binds and inhibits Dbl family guanine nucleotide exchange factors: a possible link to Rho family GTPases.Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells.Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis.Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturationRegulation of nonmuscle myosin II by tropomyosin.Nonmuscle myosin II isoforms coassemble in living cells.Differential role of nonmuscle myosin II isoforms during blebbing of MCF-7 cellsZIPK is critical for the motility and contractility of VSMCs through the regulation of nonmuscle myosin II isoforms.A point mutation in Myh10 causes major defects in heart development and body wall closureDuration of fusion pore opening and the amount of hormone released are regulated by myosin II during kiss-and-run exocytosis.Carboxyl-terminal-dependent recruitment of nonmuscle myosin II to megakaryocyte contractile ring during polyploidization.The role of vertebrate nonmuscle Myosin II in development and human disease.Protein kinase Cgamma regulates myosin IIB phosphorylation, cellular localization, and filament assemblyVascular smooth muscle phenotypic diversity and functionLoss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated miceLoad-dependent mechanism of nonmuscle myosin 2.TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation.Effects of alcohol, lithium, and homocysteine on nonmuscle myosin-II in the mouse placenta and human trophoblastsMyosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens.Drosophila non-muscle myosin II motor activity determines the rate of tissue foldingIn silico analyses and global transcriptional profiling reveal novel putative targets for Pea3 transcription factor related to its function in neurons.Distinct and redundant roles of the non-muscle myosin II isoforms and functional domains.Nonmuscle myosin IIB links cytoskeleton to IRE1α signaling during ER stress.Estrogen modulation of MgATPase activity of nonmuscle myosin-II-B filaments.Myosin IIC: a third molecular motor driving neuronal dynamics.An alternatively spliced isoform of non-muscle myosin II-C is not regulated by myosin light chain phosphorylation.
P2860
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P2860
Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Disease-associated mutations a ...... onmuscle myosins II-B and II-C
@ast
Disease-associated mutations a ...... onmuscle myosins II-B and II-C
@en
Disease-associated mutations a ...... onmuscle myosins II-B and II-C
@en-gb
Disease-associated mutations a ...... onmuscle myosins II-B and II-C
@nl
type
label
Disease-associated mutations a ...... onmuscle myosins II-B and II-C
@ast
Disease-associated mutations a ...... onmuscle myosins II-B and II-C
@en
Disease-associated mutations a ...... onmuscle myosins II-B and II-C
@en-gb
Disease-associated mutations a ...... onmuscle myosins II-B and II-C
@nl
prefLabel
Disease-associated mutations a ...... onmuscle myosins II-B and II-C
@ast
Disease-associated mutations a ...... onmuscle myosins II-B and II-C
@en
Disease-associated mutations a ...... onmuscle myosins II-B and II-C
@en-gb
Disease-associated mutations a ...... onmuscle myosins II-B and II-C
@nl
P2093
P2860
P921
P3181
P356
P1476
Disease-associated mutations a ...... onmuscle myosins II-B and II-C
@en
P2093
James R Sellers
Kye-Young Kim
Sachiyo Kawamoto
P2860
P304
22769-22775
P3181
P356
10.1074/JBC.M503488200
P407
P577
2005-04-20T00:00:00Z