Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation
about
Integrin cytoplasmic tail interactionsThe F-actin bundler α-actinin Ain1 is tailored for ring assembly and constriction during cytokinesis in fission yeastVASP, zyxin and TES are tension-dependent members of Focal Adherens Junctions independent of the α-catenin-vinculin moduleSpatiotemporal dynamics of traction forces show three contraction centers in migratory neuronsControl of cell-cell forces and collective cell dynamics by the intercellular adhesome.Persistence of fan-shaped keratocytes is a matrix-rigidity-dependent mechanism that requires α5β1 integrin engagement.Disabled-2 is required for efficient hemostasis and platelet activation by thrombin in miceMaturation of filopodia shaft adhesions is upregulated by local cycles of lamellipodia advancements and retractionsTCR Triggering Induces the Formation of Lck-RACK1-Actinin-1 Multiprotein Network Affecting Lck RedistributionPTP1B triggers integrin-mediated repression of myosin activity and modulates cell contractility.Integrin-associated complexes form hierarchically with variable stoichiometry in nascent adhesionsSeptins promote stress fiber-mediated maturation of focal adhesions and renal epithelial motility.To pull or be pulled: parsing the multiple modes of mechanotransduction.Matrix identity and tractional forces influence indirect cardiac reprogrammingRigidity sensing and adaptation through regulation of integrin types.Nanoparticle tension probes patterned at the nanoscale: impact of integrin clustering on force transmission.Physical principles of membrane remodelling during cell mechanoadaptationStonin1 mediates endocytosis of the proteoglycan NG2 and regulates focal adhesion dynamics and cell motility.Contact inhibition of locomotion and mechanical cross-talk between cell-cell and cell-substrate adhesion determine the pattern of junctional tension in epithelial cell aggregatesTropomyosin controls sarcomere-like contractions for rigidity sensing and suppressing growth on soft matrices.Strength of Neisseria meningitidis binding to endothelial cells requires highly-ordered CD147/β2-adrenoceptor clusters assembled by alpha-actinin-4.Congenital platelet disorders and understanding of platelet function.Front-Rear Polarization by Mechanical Cues: From Single Cells to Tissues.Mechanically activated Fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cellsMatrix Mechanosensing: From Scaling Concepts in 'Omics Data to Mechanisms in the Nucleus, Regeneration, and Cancer.Mechanical checkpoint for persistent cell polarization in adhesion-naive fibroblastsTalins and kindlins: partners in integrin-mediated adhesion.Direct observation of α-actinin tension and recruitment at focal adhesions during contact growth.Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate.Topography design concept of a tissue engineering scaffold for controlling cell function and fate through actin cytoskeletal modulationMechanotransduction: use the force(s).Mechanotransduction Mechanisms for Intraventricular Diastolic Vortex Forces and Myocardial Deformations: Part 2.Physical and functional interactions between a glioma cation channel and integrin-β1 require α-actinin.Regulation of integrin-mediated adhesions.Three-dimensional spherical spatial boundary conditions differentially regulate osteogenic differentiation of mesenchymal stromal cellsDynamic Regulation of α-Actinin's Calponin Homology Domains on F-ActinThe actin crosslinking protein palladin modulates force generation and mechanosensitivity of tumor associated fibroblasts.Capturing extracellular matrix properties in vitro: Microengineering materials to decipher cell and tissue level processes.The ubiquitin-proteasome system regulates focal adhesions at the leading edge of migrating cells.FHOD1 is needed for directed forces and adhesion maturation during cell spreading and migration.
P2860
Q26823123-A8EF0B5D-ECAE-42F4-9F27-BC69DAC7C656Q27304782-B0DE55CB-B42F-4235-B054-5B95BFBAE990Q27304987-0BFDDFAB-94B4-4460-9043-3D22B597C223Q27310707-C83751A0-9818-4FA8-86EA-5045A87A2ED9Q27313331-5C7DC036-E8DB-4329-9EF6-BB4B7B95064AQ27342564-C7B9AF85-F10E-4899-82CE-73A7EEAB0612Q27342751-CBF2B0C5-CF37-48E2-ABD3-0272E5EEDECFQ27348613-1209C5B1-8EB6-428A-BA50-317DEDDF6F3CQ30008827-5120505E-A0E3-4423-BF41-80EB428C6C2FQ30360988-346855C0-B5B2-4862-B4E4-3198D88FBA3BQ30371366-10328B9B-3792-4C1F-AE6A-6F8540D84D4EQ30405644-BF378944-535F-4C4C-9796-46A3D2E564C5Q30429589-8EF38DFF-3D4C-457A-B5E3-B2754B15F168Q30559231-49E82309-FFBB-47D8-BED5-DCB757242306Q30578644-CC6A384A-F98E-463C-8112-6078E72314D9Q30590254-FC7187E0-6583-453B-9A78-A6D82EFE2238Q30656470-1C2B44DD-79B8-4AC4-B90D-1C1426C16346Q30667566-1ADB415B-82A7-44A5-B530-1D737BAB22BEQ30834256-29F976C5-6604-4634-8056-60DFF6AD4B38Q30837834-83F78016-47F7-47A5-B11F-5419A4841848Q30855022-DC90CD7C-75C2-4BB4-AEC1-2D40F41B0A71Q33411778-F2EF5404-53AE-4A29-B027-4513383E8D23Q33647687-3D67B5E9-4188-4312-ACA5-F9C2C10E1455Q33692515-B525B874-A6F6-43DA-9E7B-7CD5F32D9D1AQ33726992-A4CE93F1-8462-4EDD-B191-267F95837AB7Q33922295-2D8B5447-6AB1-4E07-8614-5C57D81CA7FAQ33978054-EDD0D57A-F230-4807-9547-C3F8AA503FF4Q34127549-9CDA625E-FEBF-4BF2-BAE4-132592E6356BQ34315046-E8803D01-D8E3-42E0-AD0B-7EC725F03321Q34563167-806675D6-32C3-48EA-B89D-BDC149803ACCQ35682348-4F763489-2761-4540-A3AA-56F4568DE391Q35901064-4328D3A9-AC7A-4EC3-8235-B9AA86409CCAQ36017626-42FF0F53-6144-4A51-9FD9-C479B9040632Q36264774-CFDB9440-963E-497D-80F3-FE30FF65BD09Q36588631-3D0BE994-D3C3-4192-B3DD-46F750457DD7Q36753948-699D2471-7CF4-4117-8CFB-BC8813218757Q37050026-3EB21FF8-53C4-413A-AB94-6E0A0433B32FQ37107142-F8C93246-0842-45B2-91BF-4A83B485B953Q37388703-259F5F0B-5E47-4A16-9FC7-CEC39725D05CQ37473452-68038F8B-1735-4F3F-B966-7882DD015A3A
P2860
Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation
description
2013 nî lūn-bûn
@nan
2013 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մարտին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Integrin-dependent force trans ...... n triggers adhesion maturation
@ast
Integrin-dependent force trans ...... n triggers adhesion maturation
@en
type
label
Integrin-dependent force trans ...... n triggers adhesion maturation
@ast
Integrin-dependent force trans ...... n triggers adhesion maturation
@en
prefLabel
Integrin-dependent force trans ...... n triggers adhesion maturation
@ast
Integrin-dependent force trans ...... n triggers adhesion maturation
@en
P2093
P2860
P356
P1476
Integrin-dependent force trans ...... n triggers adhesion maturation
@en
P2093
Armando del Rio
Eileen Puklin-Faucher
Michael P Sheetz
Nicolas Biais
Nils C Gauthier
Pere Roca-Cusachs
P2860
P304
P356
10.1073/PNAS.1220723110
P407
P577
2013-03-20T00:00:00Z