Discriminating between the activities of human neutrophil elastase and proteinase 3 using serpin-derived fluorogenic substrates
about
New selective peptidyl di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases.Cleavage of p21/WAF1/CIP1 by proteinase 3 modulates differentiation of a monocytic cell line. Molecular analysis of the cleavage site.Structures of human proteinase 3 and neutrophil elastase--so similar yet so different.Utilization of the 1,2,3,5-thiatriazolidin-3-one 1,1-dioxide scaffold in the design of potential inhibitors of human neutrophil proteinase 3.Inhibitors of human neutrophil elastase based on a highly functionalized N-amino-4-imidazolidinone scaffoldViral cross-class serpin inhibits vascular inflammation and T lymphocyte fratricide; a study in rodent models in vivo and human cell lines in vitro.Inactivation of human neutrophil elastase by 1,2,5-thiadiazolidin-3-one 1,1 dioxide-based sulfonamidesActivatable Optical Probes for the Detection of Enzymes.Inhibition of serine proteases by a new class of cyclosulfamide-based carbamylating agents.Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease.A novel locust (Schistocerca gregaria) serine protease inhibitor with a high affinity for neutrophil elastase.Emerging challenges in the design of selective substrates, inhibitors and activity-based probes for indistinguishable proteases.Discriminating between the activities of human cathepsin G and chymase using fluorogenic substrates.Staphylococcus aureus protects its immune-evasion proteins against degradation by neutrophil serine proteases.Catalytic activity and inhibition of wegener antigen proteinase 3 on the cell surface of human polymorphonuclear neutrophils.Structural Determinants of the Stability of Enzyme-Responsive Polyion Complex Nanoparticles Targeting 's ElastaseDifferences in the substrate binding sites of murine and human proteinase 3 and neutrophil elastaseInfluence of Charge Distribution at the Active Site Surface on the Substrate Specificity of Human Neutrophil Protease 3 and Elastase
P2860
Q27314812-7F859A15-C017-4C71-8B7B-E9F5954DAC69Q30855520-F2A3E416-FC40-4CF5-B36B-7165089F7BFFQ33348995-AF4917A9-0569-4730-B803-33985C766B3EQ33522863-2E628942-2F4A-4B52-B1A6-0847A83C5B26Q34054400-3B6E3D4E-BBE8-4072-B6CA-2F36B1320C66Q34437925-6ADABB32-225E-4F35-BCCD-ED107AEE2EF3Q36496641-CF310CE1-79EF-44B6-9074-951F70A2E795Q36697462-84C26631-7829-40B6-BECC-E10304311362Q36803157-4FDA5FDC-538E-402F-9286-17941DE5B322Q38850115-F693D2B2-5556-40FD-9038-561925D0BA7CQ38921354-BAE93284-8CD2-4505-B986-6BB82C7D7ED8Q39067283-3923CF56-A59D-43A8-833B-6B9FD0831E70Q39539160-A9EC58FA-7095-48D5-A786-46B1F2022F99Q40975524-D8CCD8E9-8F09-4034-95E4-5A04D13D3ADBQ42550003-FFA45458-E93D-4C0E-A14E-109F34D225CAQ57171738-FD895CA6-F92D-44D4-8210-27F763582B64Q57235371-C4446801-4EB6-494D-9B0B-C97E395E8C61Q57235374-83778774-450F-471B-8BA3-8825A16AE227
P2860
Discriminating between the activities of human neutrophil elastase and proteinase 3 using serpin-derived fluorogenic substrates
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Discriminating between the act ...... derived fluorogenic substrates
@ast
Discriminating between the act ...... derived fluorogenic substrates
@en
Discriminating between the act ...... derived fluorogenic substrates
@en-gb
Discriminating between the act ...... derived fluorogenic substrates
@nl
type
label
Discriminating between the act ...... derived fluorogenic substrates
@ast
Discriminating between the act ...... derived fluorogenic substrates
@en
Discriminating between the act ...... derived fluorogenic substrates
@en-gb
Discriminating between the act ...... derived fluorogenic substrates
@nl
prefLabel
Discriminating between the act ...... derived fluorogenic substrates
@ast
Discriminating between the act ...... derived fluorogenic substrates
@en
Discriminating between the act ...... derived fluorogenic substrates
@en-gb
Discriminating between the act ...... derived fluorogenic substrates
@nl
P2093
P2860
P356
P1476
Discriminating between the act ...... derived fluorogenic substrates
@en
P2093
Eric Hazouard
Francis Gauthier
Luiz Juliano
Marie Lise Jourdan
Martine Ferrandiere
Michele Brillard-Bourdet
Sylvie Attucci
P2860
P304
39074-39081
P356
10.1074/JBC.M202918200
P407
P577
2002-07-11T00:00:00Z