Cell surface-bound elastase and cathepsin G on human neutrophils: a novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases
about
Discriminating between the activities of human neutrophil elastase and proteinase 3 using serpin-derived fluorogenic substratesConstitutive and inducible expression of SKALP/elafin provides anti-elastase defense in human epitheliaCytochalasin B triggers a novel pertussis toxin sensitive pathway in TNF-alpha primed neutrophilsNeutrophil elastase and matrix metalloproteinase 12 in cystic fibrosis lung diseaseNeutrophils in type 1 diabetesNeutrophil plasticity enables the development of pathological microenvironments: implications for cystic fibrosis airway diseasePro-collagenase-1 (matrix metalloproteinase-1) binds the alpha(2)beta(1) integrin upon release from keratinocytes migrating on type I collagenCathepsin G activity lowers plasma LDL and reduces atherosclerosisCathepsin G inhibitor prevents ultraviolet B-induced photoaging in hairless mice via inhibition of fibronectin fragmentationDifferent proteolytic mechanisms involved in Fc gamma RIIIb shedding from human neutrophilsHypoxia upregulates neutrophil degranulation and potential for tissue injuryHow immune peptidases change specificity: cathepsin G gained tryptic function but lost efficiency during primate evolutionPlasmodium falciparum infection induces expression of a mosquito salivary protein (Agaphelin) that targets neutrophil function and inhibits thrombosis without impairing hemostasisProteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin.Cleavage of the CD11b extracellular domain by the leukocyte serprocidins is critical for neutrophil detachment during chemotaxis.Neutrophil elastase cleaves epithelial cadherin in acutely injured lung epitheliumIdentification of immunoreactive tissue prokallikrein on the surface membrane of human neutrophils.Rapid inactivation of stromal cell-derived factor-1 by cathepsin G associated with lymphocytes.Actions of heparin that may affect the malignant process.Elastase, α1-proteinase inhibitor, and interleukin-8 in children and young adults with end-stage kidney disease undergoing continuous ambulatory peritoneal dialysis.The role of protegrins and other elastase-activated polypeptides in the bactericidal properties of porcine inflammatory fluids.Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammationLeukocyte proteinases in wound healing: roles in physiologic and pathologic processes.Mechanism of heparin acceleration of tissue inhibitor of metalloproteases-1 (TIMP-1) degradation by the human neutrophil elastaseADAM9 is a novel product of polymorphonuclear neutrophils: regulation of expression and contributions to extracellular matrix protein degradation during acute lung injury.Functional characterization of polymorphisms in the peptidase inhibitor 3 (elafin) gene and validation of their contribution to risk of acute respiratory distress syndrome.Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases.Glucocorticosteroids differentially regulate MMP-9 and neutrophil elastase in COPD.Leukocyte elastase: physiological functions and role in acute lung injury.Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosis-like lung disease.Squamous cell carcinoma antigen 2 is a novel serpin that inhibits the chymotrypsin-like proteinases cathepsin G and mast cell chymase.Neutrophil elastase: path clearer, pathogen killer, or just pathologic?A novel notch protein, N2N, targeted by neutrophil elastase and implicated in hereditary neutropeniaTumor necrosis factor alpha activates release of B lymphocyte stimulator by neutrophils infiltrating the rheumatoid jointα-1-antitrypsin variants and the proteinase/antiproteinase imbalance in chronic obstructive pulmonary disease.Neutrophil transmigration triggers repair of the lung epithelium via beta-catenin signaling.Assessment of airway neutrophils by sputum colour: correlation with airways inflammation.Porcine polymorphonuclear leukocytes generate extracellular microbicidal activity by elastase-mediated activation of secreted proprotegrins.Mature cystic fibrosis airway neutrophils suppress T cell function: evidence for a role of arginase 1 but not programmed death-ligand 1.Pathogenic factors in vascular dementia and Alzheimer's disease. Multiple actions of heparin that probably are beneficial.
P2860
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P2860
Cell surface-bound elastase and cathepsin G on human neutrophils: a novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases
description
1995 nî lūn-bûn
@nan
1995 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Cell surface-bound elastase an ...... activity of serine proteinases
@ast
Cell surface-bound elastase an ...... activity of serine proteinases
@en
Cell surface-bound elastase an ...... activity of serine proteinases
@nl
type
label
Cell surface-bound elastase an ...... activity of serine proteinases
@ast
Cell surface-bound elastase an ...... activity of serine proteinases
@en
Cell surface-bound elastase an ...... activity of serine proteinases
@nl
prefLabel
Cell surface-bound elastase an ...... activity of serine proteinases
@ast
Cell surface-bound elastase an ...... activity of serine proteinases
@en
Cell surface-bound elastase an ...... activity of serine proteinases
@nl
P2093
P2860
P3181
P356
P1476
Cell surface-bound elastase an ...... activity of serine proteinases
@en
P2093
E J Campbell
M A Campbell
P L Sannes
S S Boukedes
P2860
P304
P3181
P356
10.1083/JCB.131.3.775
P407
P577
1995-11-01T00:00:00Z