Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation
about
Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stressTyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase.Nck1 depletion induces activation of the PI3K/Akt pathway by attenuating PTP1B protein expression.[A uNick protein].Nck adapter proteins: functional versatility in T cellsNephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization.Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress.Candidates for tumor markers of cervical cancer discovered by proteomic analysis.OSU-03012 sensitizes breast cancers to lapatinib-induced cell killing: a role for Nck1 but not Nck2.A review of the mammalian unfolded protein response.Endoplasmic reticulum stress signaling in mammalian oocytes and embryos: life in balanceCellular response to endoplasmic reticulum stress: a matter of life or death.Endoplasmic reticulum stress upregulates protein tyrosine phosphatase 1B and impairs glucose uptake in cultured myotubesCellular mechanisms of endoplasmic reticulum stress signaling in health and disease. 3. Orchestrating the unfolded protein response in oncogenesis: an update.Deletion of eIF2β lysine stretches creates a dominant negative that affects the translation and proliferation in human cell line: A tool for arresting the cell growth.Cell-type variation in stress responses as a consequence of manipulating GRP78 expression in neuroectodermal cells.Interaction of Nck1 and PERK phosphorylated at Y⁵⁶¹ negatively modulates PERK activity and PERK regulation of pancreatic β-cell proinsulin content.Induction of apoptosis by the Ste20-like kinase SLK, a germinal center kinase that activates apoptosis signal-regulating kinase and p38.The N-terminal domain of the human eIF2beta subunit and the CK2 phosphorylation sites are required for its function.Deletion of Nck1 attenuates hepatic ER stress signaling and improves glucose tolerance and insulin signaling in liver of obese mice.A quantitative proteomic analysis of cellular responses to high glucose media in Chinese hamster ovary cells.Nck-1 selectively modulates eIF2alphaSer51 phosphorylation by a subset of eIF2alpha-kinases.Inhibition of IRE1α-mediated XBP1 mRNA cleavage by XBP1 reveals a novel regulatory process during the unfolded protein response.Role of the Endoplasmic Reticulum Pathway in the Medial Prefrontal Cortex in Post-Traumatic Stress Disorder Model Rats.Thinking Outside the Box.
P2860
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P2860
Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation
description
2004 nî lūn-bûn
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2004 թուականի Մարտին հրատարակուած գիտական յօդուած
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2004 թվականի մարտին հրատարակված գիտական հոդված
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2004年の論文
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2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
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name
Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation
@ast
Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation
@en
Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation
@en-gb
Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation
@nl
type
label
Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation
@ast
Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation
@en
Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation
@en-gb
Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation
@nl
prefLabel
Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation
@ast
Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation
@en
Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation
@en-gb
Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation
@nl
P2093
P2860
P921
P356
P1476
Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation
@en
P2093
Duc Thang Nguyên
Eric Cardin
Eric Chevet
Louise Larose
Sem Kebache
P2860
P304
P356
10.1074/JBC.M310535200
P407
P577
2004-03-05T00:00:00Z