Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
about
The HAC1 gene from Pichia pastoris: characterization and effect of its overexpression on the production of secreted, surface displayed and membrane proteinsLHS1 and SIL1 provide a lumenal function that is essential for protein translocation into the endoplasmic reticulumERp44, a novel endoplasmic reticulum folding assistant of the thioredoxin familyDimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stressTEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulumNrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagyA membrane protein required for dislocation of misfolded proteins from the ERA membrane protein complex mediates retro-translocation from the ER lumen into the cytosolDefining human ERAD networks through an integrative mapping strategyRole of ubiquilin associated with protein-disulfide isomerase in the endoplasmic reticulum in stress-induced apoptotic cell deathA synthetic biology approach identifies the mammalian UPR RNA ligase RtcBNck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translationEndoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3betaCharacterization of mammalian Ecm29, a 26 S proteasome-associated protein that localizes to the nucleus and membrane vesiclesA ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of ParkinCHAC1/MGC4504 is a novel proapoptotic component of the unfolded protein response, downstream of the ATF4-ATF3-CHOP cascadeERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stressERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein CHuman HRD1 protects against ER stress-induced apoptosis through ER-associated degradationRNF185 is a novel E3 ligase of endoplasmic reticulum-associated degradation (ERAD) that targets cystic fibrosis transmembrane conductance regulator (CFTR)Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERADInvolvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell deathA novel ER alpha-mannosidase-like protein accelerates ER-associated degradationMultiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane.Proteins of the endoplasmic-reticulum-associated degradation pathway: domain detection and function predictionDistinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein responseCharacterization of an ERAD gene as VPS30/ATG6 reveals two alternative and functionally distinct protein quality control pathways: one for soluble Z variant of human alpha-1 proteinase inhibitor (A1PiZ) and another for aggregates of A1PiZ.Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathwayCell wall assembly in Saccharomyces cerevisiaeThe role of protease inhibitors in the pathogenesis of HIV-associated lipodystrophy: cellular mechanisms and clinical implicationsA conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradationA haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycinInhibition of p97-dependent protein degradation by Eeyarestatin IOne step at a time: endoplasmic reticulum-associated degradationIRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein responseOxidative protein folding in eukaryotes: mechanisms and consequencesMisfolded proteins are sorted by a sequential checkpoint mechanism of ER quality controlSCFCdc4-mediated degradation of the Hac1p transcription factor regulates the unfolded protein response in Saccharomyces cerevisiaeUnfolded protein response in a Drosophila model for retinal degenerationSynoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathy
P2860
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P2860
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
description
2000 nî lūn-bûn
@nan
2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Functional and genomic analyse ...... and ER-associated degradation
@ast
Functional and genomic analyse ...... and ER-associated degradation
@en
Functional and genomic analyse ...... and ER-associated degradation
@nl
type
label
Functional and genomic analyse ...... and ER-associated degradation
@ast
Functional and genomic analyse ...... and ER-associated degradation
@en
Functional and genomic analyse ...... and ER-associated degradation
@nl
prefLabel
Functional and genomic analyse ...... and ER-associated degradation
@ast
Functional and genomic analyse ...... and ER-associated degradation
@en
Functional and genomic analyse ...... and ER-associated degradation
@nl
P2093
P3181
P1433
P1476
Functional and genomic analyse ...... and ER-associated degradation
@en
P2093
D J Lockhart
J S Weissman
K J Travers
P304
P3181
P356
10.1016/S0092-8674(00)80835-1
P407
P577
2000-04-28T00:00:00Z