Aldo-keto reductase family 1 B10 affects fatty acid synthesis by regulating the stability of acetyl-CoA carboxylase-alpha in breast cancer cells
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O-GlcNAcylation and the Metabolic Shift in High-Proliferating Cells: All the Evidence Suggests that Sugars Dictate the Flux of Lipid Biogenesis in Tumor ProcessesStructure and function of biotin-dependent carboxylasesIdentification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug designStructural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10Aldo-Keto Reductases 1B in Adrenal Cortex PhysiologyAn initial map of chromosomal segmental copy number variations in the chickenAldo-Keto Reductase Family 1 Member B10 Inhibitors: Potential Drugs for Cancer Treatment.Aldo-keto reductase family 1 member B8 is secreted via non-classical pathway.Smoking-induced upregulation of AKR1B10 expression in the airway epithelium of healthy individuals.Molecular analysis of thymoma.Gene expression profiling unravels cancer-related hepatic molecular signatures in steatohepatitis but not in steatosisHuman aldo-keto reductases 1B1 and 1B10: a comparative study on their enzyme activity toward electrophilic carbonyl compounds.Impaired self-renewal and increased colitis and dysplastic lesions in colonic mucosa of AKR1B8-deficient mice.Genetic variants in AKR1B10 associate with human eating behavior.Aldo-Keto Reductases 1B in Endocrinology and Metabolism.Dysregulated lipid metabolism in cancer.Transcriptomic and proteomic profiling of KEAP1 disrupted and sulforaphane-treated human breast epithelial cells reveals common expression profiles.Structure and promoter characterization of aldo-keto reductase family 1 B10 gene.TGFβ-induced switch from adipogenic to osteogenic differentiation of human mesenchymal stem cells: identification of drug targets for prevention of fat cell differentiation.Acetyl-CoA carboxylase-alpha inhibitor TOFA induces human cancer cell apoptosisAldo-keto reductase family 1 B10 protein detoxifies dietary and lipid-derived alpha, beta-unsaturated carbonyls at physiological levels.Heat shock protein 90-α mediates aldo-keto reductase 1B10 (AKR1B10) protein secretion through secretory lysosomes.Aldo-keto reductase family 1 member B10 promotes cell survival by regulating lipid synthesis and eliminating carbonyls.AKR1B10 promotes breast cancer metastasis through integrin α5/δ-catenin mediated FAK/Src/Rac1 signaling pathway.Role of abnormal lipid metabolism in development, progression, diagnosis and therapy of pancreatic cancer.High expression of AKR1B10 predicts low risk of early tumor recurrence in patients with hepatitis B virus-related hepatocellular carcinoma.Epidermal growth factor induces tumour marker AKR1B10 expression through activator protein-1 signalling in hepatocellular carcinoma cells.Human aldo-keto reductases: structure, substrate specificity and roles in tumorigenesis.The acetyl-CoA carboxylase enzyme: a target for cancer therapy?Roles of aldo-keto reductases 1B10 and 1C3 and ATP-binding cassette transporter in docetaxel tolerance.AKR1B10 overexpression in breast cancer: association with tumor size, lymph node metastasis and patient survival and its potential as a novel serum marker.V-AKT murine thymoma viral oncogene homolog/mammalian target of rapamycin activation induces a module of metabolic changes contributing to growth in insulin-induced hepatocarcinogenesis.Overexpression and oncogenic function of aldo-keto reductase family 1B10 (AKR1B10) in pancreatic carcinoma.Dual role of insulin-like growth factor-1 in acetyl-CoA carboxylase-alpha activity in human colon cancer cells HCT-8: downregulating its expression and phosphorylation.Aldo-keto reductase 1B10 protects human colon cells from DNA damage induced by electrophilic carbonyl compounds.Aldo-Keto Reductase 1B10 and Its Role in Proliferation Capacity of Drug-Resistant CancersEffects of ligand binding on the stability of aldo-keto reductases: Implications for stabilizer or destabilizer chaperones.Aldo-keto reductase family 1, member B10 is secreted through a lysosome-mediated non-classical pathway.Murine aldo-keto reductase family 1 subfamily B: identification of AKR1B8 as an ortholog of human AKR1B10.Inhibiting proliferation and migration of lung cancer using small interfering RNA targeting on Aldo-keto reductase family 1 member B10.
P2860
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P2860
Aldo-keto reductase family 1 B10 affects fatty acid synthesis by regulating the stability of acetyl-CoA carboxylase-alpha in breast cancer cells
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Aldo-keto reductase family 1 B ...... e-alpha in breast cancer cells
@ast
Aldo-keto reductase family 1 B ...... e-alpha in breast cancer cells
@en
Aldo-keto reductase family 1 B ...... e-alpha in breast cancer cells
@en-gb
Aldo-keto reductase family 1 B ...... e-alpha in breast cancer cells
@nl
type
label
Aldo-keto reductase family 1 B ...... e-alpha in breast cancer cells
@ast
Aldo-keto reductase family 1 B ...... e-alpha in breast cancer cells
@en
Aldo-keto reductase family 1 B ...... e-alpha in breast cancer cells
@en-gb
Aldo-keto reductase family 1 B ...... e-alpha in breast cancer cells
@nl
prefLabel
Aldo-keto reductase family 1 B ...... e-alpha in breast cancer cells
@ast
Aldo-keto reductase family 1 B ...... e-alpha in breast cancer cells
@en
Aldo-keto reductase family 1 B ...... e-alpha in breast cancer cells
@en-gb
Aldo-keto reductase family 1 B ...... e-alpha in breast cancer cells
@nl
P2093
P2860
P3181
P356
P1476
Aldo-keto reductase family 1 B ...... e-alpha in breast cancer cells
@en
P2093
Deliang Cao
Duan-Fang Liao
Ji-Ming Cheng
Krishna Rao
Ruilan Yan
P2860
P304
P3181
P356
10.1074/JBC.M707650200
P407
P577
2008-02-08T00:00:00Z