Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal - Test2 - elhamkhani - TriplyDB

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

http://www.wikidata.org/entity/Q24529830

about

ACC2 is expressed at high levels in human white adipose and has an isoform with a novel N-terminus [corrected]Aldo-keto reductase family 1 B10 affects fatty acid synthesis by regulating the stability of acetyl-CoA carboxylase-alpha in breast cancer cells Polyunsaturated fatty acid metabolism in prostate cancer The human ACC2 CT-domain C-terminus is required for full functionality and has a novel twist Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism Role of bile acids in the regulation of the metabolic pathways Structure and function of biotin-dependent carboxylases Energy metabolism in the liver Structure-guided Inhibitor Design for Human Acetyl-coenzyme A Carboxylase by Interspecies Active Site Conversion Drosophila melanogaster Acetyl-CoA-carboxylase sustains a fatty acid-dependent remote signal to waterproof the respiratory system Reduced heart size and increased myocardial fuel substrate oxidation in ACC2 mutant mice Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice ID2 (inhibitor of DNA binding 2) is a rhythmically expressed transcriptional repressor required for circadian clock output in mouse liver Transcriptional changes associated with lack of lipid synthesis in parasitoids Regulator of fatty acid metabolism, acetyl coenzyme a carboxylase 1, controls T cell immunity.Leptin contributes to the adaptive responses of mice to high-fat diet intake through suppressing the lipogenic pathway.Recombinant yeast screen for new inhibitors of human acetyl-CoA carboxylase 2 identifies potential drugs to treat obesity.Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy.Metabolic genes in cancer: their roles in tumor progression and clinical implications Lipid metabolites as metabolic messengers in inter-organ communication.Lipid oversupply, selective insulin resistance, and lipotoxicity: molecular mechanisms Genetic control of de novo lipogenesis: role in diet-induced obesity The role of mitochondrial DNA copy number in mammalian fertility.Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue.Acyl-CoA binding protein gene ablation induces pre-implantation embryonic lethality in mice.Profiling spermatogenic failure in adult testes bearing Sox9-deficient Sertoli cells identifies genes involved in feminization, inflammation and stress.Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation.Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin.Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis Association between phosphorylated AMP-activated protein kinase and acetyl-CoA carboxylase expression and outcome in patients with squamous cell carcinoma of the head and neck.Dietary fat impacts fetal growth and metabolism: uptake of chylomicron remnant core lipids by the placenta.De novo lipogenesis in metabolic homeostasis: More friend than foe?Effect of Chronic Pioglitazone Treatment on Hepatic Gene Expression Profile in Obese C57BL/6J Mice.Acetyl-CoA carboxylase 2-/- mutant mice are protected against fatty liver under high-fat, high-carbohydrate dietary and de novo lipogenic conditions.Emerging roles for specific fatty acids in developmental processes.Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity Concurrence in the ability for lipid synthesis between life stages in insects.The coordination of nuclear and mitochondrial communication during aging and calorie restriction Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice.Acetyl-coenzyme A carboxylases: versatile targets for drug discovery.

P2860

Q21143880-CD617E18-F3B1-4DFA-881B-7715DFAEF735 Q24302032-853059F9-83EE-46F2-A0D5-6FED5B174AD6 Q24629893-5E7268F0-A8D7-4934-9510-87D01FEDD588 Q24652953-E0C55508-FEA7-4477-87CE-CC6FF916EFBA Q24653884-484F2A7F-F557-4266-AB4A-8CB13E376049 Q26738976-88425414-A58D-4BDF-92A8-C841116BEDC2 Q26851762-273121E3-05C1-4CF6-BCB5-FCA41184B470 Q26996783-DEE85F6F-1A48-428B-AE81-2BA15FAFD3E6 Q27674547-DEEBD066-A304-45BD-B30B-77265BAFADD8 Q28483041-CBCBDB22-6601-491C-9CAE-B3953273A58F Q28584714-CDC7BDB0-B53A-4617-A5C2-853818D34A33 Q28589371-1150394F-9866-4380-9C4C-4522FB5DF691 Q28591766-F181E2A4-94B3-4CA1-9070-C6BE8BB631D5 Q28710479-35493500-0741-4F88-8DAD-77E3DA9BBD3E Q30406101-61CBD9CA-7C89-44B2-9286-B85AA92F3D07 Q33499679-D842C4BB-0D2F-4847-9BC0-39451E17DAD7 Q33571309-0B9D8FAD-B1B9-445B-8EB6-67D0724E0721 Q33675261-A3B2DA09-9B83-4919-860D-18AFA378DF16 Q33772469-DBC4000B-05E3-41A7-9B8E-552DB76EA6F5 Q33831533-78B43603-9073-4577-AB71-F011414A5999 Q33843550-71D39F3F-34AE-475F-8A21-97B9022EC3BA Q33867059-0E5A6D8B-43B6-4604-B763-1A7EB9251331 Q33926626-017FA626-9B8A-4BAA-BA88-CA1183D0AC47 Q34056185-A2EB40B7-D390-43D9-8B09-6140C1F06F72 Q34383471-132F562C-C542-4B9A-9A9E-9D611D19F78C Q34506834-7B083516-6F3B-4A41-902A-0D1E634DBD4F Q34543236-E3D6D8D0-A738-42CA-A9FC-CDCF4001EAED Q34657137-91995370-B9E0-40C3-AA49-B816D1E2C24B Q35039363-C14284BA-CB7B-47CF-9F44-2CCE1AAF9B62 Q35158141-AD962A86-CF91-42E0-8505-CA1955F06517 Q35159373-9CA81800-02DC-4B7E-8D3E-48FBB17EB96D Q35573584-BC3E26A3-05D9-40FB-8069-9E2ADF35537F Q35813795-285E7FE8-F871-4149-90B6-421861BEF757 Q35874567-56725DF9-44DF-4A1C-B10D-EE2C18A4F07B Q35882127-51F59E96-E968-4BF0-8BB0-5900C8340448 Q36082167-FD7BB379-8350-4504-A063-F4257B7E577B Q36345498-8B6C32F9-8429-4744-9DA2-0CFF33548123 Q36433751-E912F618-154E-4644-8AF3-67886A06194B Q36479005-0BB2E530-15AE-425E-9A48-6B05265EEC6D Q36597445-53AE5B2C-976F-4DEA-A849-47D2DC6CF5B9

P2860

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

http://www.wikidata.org/entity/Q24529830

description

2005 nî lūn-bûn

@nan

2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

@ast

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

@en

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

@en-gb

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

@nl

type

label

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

@ast

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

@en

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

@en-gb

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

@nl

prefLabel

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

@ast

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

@en

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

@en-gb

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

@nl

P1433

Q24529830-C6B5677B-7FF9-476B-B3A4-C84F01025902

P1476

Q24529830-0E89DFCC-8AFA-45AA-8036-872DB4FCC28F

P2093

Q24529830-1CFE9491-C385-4E5B-914F-0419F8C52C57

Q24529830-9C2197C5-11EC-4944-9793-1ECFCCDA8669

Q24529830-B007DA82-2DF5-496A-8309-7D8627859D34

Q24529830-C75C2293-393B-4E65-86DB-4DC3DB8045F2

Q24529830-CF6B8686-CCD0-4115-A192-B1FEFE0D9D81

P2860

Q24529830-026E7220-A46A-4220-B184-B1EF09E93C31

Q24529830-083FFDEA-EF6E-4A9D-8BB5-47CFA288A6E2

Q24529830-0EB94E08-C51E-4448-ABE2-4D717EBE41F4

Q24529830-0EE92109-20FA-495F-959D-C775D0BD7F5B

Q24529830-0F02A2D7-E0BB-4D8A-9E37-4589A94B0021

Q24529830-10648691-67E8-4717-B89E-81AC4FDA3126

Q24529830-15B0FD45-A4AF-40ED-AFA9-60094970E828

Q24529830-18E11021-636B-49B4-993E-199512A60961

Q24529830-248DF919-744E-4290-BBA6-EFC5516D2C62

Q24529830-2CA2D41F-1CB1-4374-A224-9D9047A4D821

P304

Q24529830-CFDF7320-CBA1-4056-BF5C-0C4E185FFD8C

P31

Q24529830-87665918-7FD0-4DA0-940E-B0CAA76A136B

P3181

Q24529830-BA87A77E-BE8F-4154-A7E3-6D69A923D305

P356

Q24529830-A07C740E-56AF-492D-B5C7-0D53BC15E6EF

P407

Q24529830-85193432-AF44-4982-B087-A9E24286362C

P433

Q24529830-6AB171D6-6CDA-43C2-A765-FD87B9F90ABD

P478

Q24529830-814B2C7B-EABC-4359-A0B8-806DEFB21C97

P50

Q24529830-36D070A0-758B-4ABB-9CF8-53ECE7284279

Q24529830-669EC60F-C24A-4759-910C-9AA57073AF73

P577

Q24529830-454C8076-5A7C-46E9-A2AE-88779B97E756

P5875

Q24529830-F4BD4E22-E179-4ED3-A2BB-583AB5F91E3F

P698

Q24529830-3CBF0A2E-9C26-4E42-A917-5E3D8C99F1AE

P932

Q24529830-6BF882A1-7512-4F7B-8F6C-D05CA0B976A0

P3181

P356

PNAS.0505714102

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

@en

P2093

Martin M Matzuk

http://www.w3.org/2001/XMLSchema#string

Parichher Kordari

http://www.w3.org/2001/XMLSchema#string

Salih J Wakil

http://www.w3.org/2001/XMLSchema#string

WonKeun Oh

http://www.w3.org/2001/XMLSchema#string

Ziwei Gu

http://www.w3.org/2001/XMLSchema#string

P2860

The subcellular localization of acetyl-CoA carboxylase 2

Human acetyl-CoA carboxylase: characterization, molecular cloning, and evidence for two isoforms

Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets

Acetyl-CoA carboxylase from yeast is an essential enzyme and is regulated by factors that control phospholipid metabolism.

Cloning of the yeast FAS3 gene and primary structure of yeast acetyl-CoA carboxylase.

Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2

The 1993 Merck Frosst Award. Acetyl-CoA carboxylase: an important regulator of fatty acid oxidation in the heart

Isolation and characterization of a novel acetyl-CoA carboxylase kinase from rat liver

Contraction-induced changes in acetyl-CoA carboxylase and 5'-AMP-activated kinase in skeletal muscle

Glucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout mice

P304

12011-12016

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1629555

http://www.w3.org/2001/XMLSchema#string

P356

10.1073/PNAS.0505714102

http://www.w3.org/2001/XMLSchema#string

P407

P433

34

http://www.w3.org/2001/XMLSchema#string

P478

102

http://www.w3.org/2001/XMLSchema#string

P50

Lutfi Abu-Elheiga

Tattym E. Shaikenov

P577

2005-08-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7657998

http://www.w3.org/2001/XMLSchema#string

P698

16103361

http://www.w3.org/2001/XMLSchema#string

P932

1189351

http://www.w3.org/2001/XMLSchema#string