Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia
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Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cellsMolecular pathogenesis of pulmonary arterial hypertensionHereditary haemorrhagic telangiectasia: current views on genetics and mechanisms of diseaseUpregulated genes in sporadic, idiopathic pulmonary arterial hypertension.Targeting BMP signalling in cardiovascular disease and anaemiaThe molecular genetics and cellular mechanisms underlying pulmonary arterial hypertensionThe genetics of pulmonary arterial hypertensionPulmonary arterial hypertension: a comparison between children and adultsPulmonary arterial hypertension associated with congenital heart disease and Eisenmenger syndrome: current practice in pediatricsFunctional and splicing defect analysis of 23 ACVRL1 mutations in a cohort of patients affected by Hereditary Hemorrhagic TelangiectasiaHereditary hemorrhagic telangiectasia: an overview of diagnosis, management, and pathogenesisMutations of NOTCH3 in childhood pulmonary arterial hypertensionHypoxia induces alteration of bone morphogenetic protein receptor signaling in pulmonary artery endothelial cellALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2Mutational and clinical analysis of the ENG gene in patients with pulmonary arterial hypertensionWorld Health Organization Group I Pulmonary Hypertension: Epidemiology and Pathophysiology.Mutation study of Spanish patients with hereditary hemorrhagic telangiectasiaPulmonary arterial hypertension: the clinical syndrome.Applications of small molecule BMP inhibitors in physiology and disease.ANG-1 TIE-2 and BMPR signalling defects are not seen in the nitrofen model of pulmonary hypertension and congenital diaphragmatic hernia.Pulmonary hypertension: diagnosis and managementEndoglin and activin receptor-like-kinase 1 are co-expressed in the distal vessels of the lung: implications for two familial vascular dysplasias, HHT and PAH.Three novel BMPR2 mutations associated with advanced pulmonary arterial hypertensionEndothelial follistatin-like-1 regulates the postnatal development of the pulmonary vasculature by modulating BMP/Smad signaling.Heritable forms of pulmonary arterial hypertension.Transforming growth factor-β inhibition attenuates pulmonary arterial hypertension in rats.Regulation of bone morphogenetic protein 9 (BMP9) by redox-dependent proteolysis.Bone Morphogenetic Protein (BMP) signaling in development and human diseasesStrategic plan for lung vascular research: An NHLBI-ORDR Workshop Report.The economic burden of pulmonary arterial hypertension (PAH) in the US on payers and patients.Neonatal hyperoxia causes pulmonary vascular disease and shortens life span in aging miceDisruption of PPARγ/β-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survivalSelective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension.Hereditary hemorrhagic telangiectasia: an overview of diagnosis and management in the molecular era for clinicians.Accurate genetic diagnosis of Finnish pulmonary arterial hypertension patients using oligonucleotide-selective sequencing.Estrogen exposure, obesity and thyroid disease in women with severe pulmonary hypertension.Hereditary hemorrhagic telangiectasia, a vascular dysplasia affecting the TGF-beta signaling pathwayRole of the TGF-beta/Alk5 signaling pathway in monocrotaline-induced pulmonary hypertension.Transforming growth factor-β inhibition and endothelin receptor blockade in rats with monocrotaline-induced pulmonary hypertension.Mutations of TGFbeta signaling molecules in human disease.
P2860
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P2860
Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
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2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
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2003年論文
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2003年论文
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name
Molecular and functional analy ...... ry haemorrhagic telangiectasia
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Molecular and functional analy ...... ry haemorrhagic telangiectasia
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Molecular and functional analy ...... ry haemorrhagic telangiectasia
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Molecular and functional analy ...... ry haemorrhagic telangiectasia
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type
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Molecular and functional analy ...... ry haemorrhagic telangiectasia
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Molecular and functional analy ...... ry haemorrhagic telangiectasia
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Molecular and functional analy ...... ry haemorrhagic telangiectasia
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Molecular and functional analy ...... ry haemorrhagic telangiectasia
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Molecular and functional analy ...... ry haemorrhagic telangiectasia
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Molecular and functional analy ...... ry haemorrhagic telangiectasia
@en
Molecular and functional analy ...... ry haemorrhagic telangiectasia
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Molecular and functional analy ...... ry haemorrhagic telangiectasia
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Molecular and functional analy ...... ry haemorrhagic telangiectasia
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P2093
A Räisänen-Sokolowski
C G Elliott
I M Robbins
J A Flanagan
R E Harrison
P2860
P304
P3181
P356
10.1136/JMG.40.12.865
P407
P577
2003-12-01T00:00:00Z