PKD1 phosphorylation-dependent degradation of SNAIL by SCF-FBXO11 regulates epithelial-mesenchymal transition and metastasis
about
Multifunctional DDX3: dual roles in various cancer development and its related signaling pathwaysProtein Kinase D Enzymes as Regulators of EMT and Cancer Cell InvasionTargeting the Nuclear Export Protein XPO1/CRM1 Reverses Epithelial to Mesenchymal TransitionRegulation of epithelial-mesenchymal transition through epigenetic and post-translational modificationsAKT-ions with a TWIST between EMT and METTackling Cancer Stem Cells via Inhibition of EMT Transcription FactorsDeregulation of F-box proteins and its consequence on cancer development, progression and metastasis.Calmodulin promotes matrix metalloproteinase 9 production and cell migration by inhibiting the ubiquitination and degradation of TBC1D3 oncoprotein in human breast cancer cells.Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions.FBXO11 promotes ubiquitination of the Snail family of transcription factors in cancer progression and epidermal development.Effective Targeting of Estrogen Receptor-Negative Breast Cancers with the Protein Kinase D Inhibitor CRT0066101.The ectopic expression of Snail in MDBK cells does not induce epithelial-mesenchymal transition.A genome-scale CRISPR-Cas9 screening method for protein stability reveals novel regulators of Cdc25AMiRNA-621 sensitizes breast cancer to chemotherapy by suppressing FBXO11 and enhancing p53 activity.Functional and therapeutic significance of protein kinase D enzymes in invasive breast cancer.FBXO32 suppresses breast cancer tumorigenesis through targeting KLF4 to proteasomal degradation.The Emerging Role of ABL Kinases in Solid Tumors.The positive feedback between Snail and DAB2IP regulates EMT, invasion and metastasis in colorectal cancer.Small molecule therapeutics targeting F-box proteins in cancer.A Switch in Akt Isoforms Is Required for Notch-Induced Snail1 Expression and Protection from Cell DeathProtein Kinase D1 regulates focal adhesion dynamics and cell adhesion through Phosphatidylinositol-4-phosphate 5-kinase type-l γ.Role of thioredoxin reductase 1 in dysplastic transformation of human breast epithelial cells triggered by chronic oxidative stressCELF1 is a central node in post-transcriptional regulatory programmes underlying EMTCDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation.Epithelial-mesenchymal transition is regulated at post-transcriptional levels by transforming growth factor-β signaling during tumor progression.The relevance of EMT in breast cancer metastasis: Correlation or causality?Pancreatic cancer stem cells.MicroRNA regulation of F-box proteins and its role in cancer.MicroRNA-153 inhibits tumor progression in esophageal squamous cell carcinoma by targeting SNAI1.Epithelial to Mesenchymal Transition in Renal Cell Carcinoma: Implications for Cancer Therapy.E-Cadherin Facilitates Protein Kinase D1 Activation and Subcellular Localization.Epithelial-to-Pericyte Transition in Cancer.Diffusion kurtosis imaging evaluating epithelial-mesenchymal transition in colorectal carcinoma xenografts model: a preliminary study.Complex Determinants of Epithelial: Mesenchymal Phenotypic Plasticity in Ovarian Cancer.Epithelial to mesenchymal transition in tumor cells as consequence of phenotypic instability.A20 promotes metastasis of aggressive basal-like breast cancers through multi-monoubiquitylation of Snail1.Regulation of FBXO4-mediated ICAM-1 protein stability in metastatic breast cancer.FBXO32 promotes microenvironment underlying epithelial-mesenchymal transition via CtBP1 during tumour metastasis and brain development.A novel interaction of PAK4 with PPARγ to regulate Nox1 and radiation-induced epithelial-to-mesenchymal transition in glioma.
P2860
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P2860
PKD1 phosphorylation-dependent degradation of SNAIL by SCF-FBXO11 regulates epithelial-mesenchymal transition and metastasis
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
PKD1 phosphorylation-dependent ...... ymal transition and metastasis
@ast
PKD1 phosphorylation-dependent ...... ymal transition and metastasis
@en
PKD1 phosphorylation-dependent ...... ymal transition and metastasis
@nl
type
label
PKD1 phosphorylation-dependent ...... ymal transition and metastasis
@ast
PKD1 phosphorylation-dependent ...... ymal transition and metastasis
@en
PKD1 phosphorylation-dependent ...... ymal transition and metastasis
@nl
prefLabel
PKD1 phosphorylation-dependent ...... ymal transition and metastasis
@ast
PKD1 phosphorylation-dependent ...... ymal transition and metastasis
@en
PKD1 phosphorylation-dependent ...... ymal transition and metastasis
@nl
P2093
P2860
P3181
P1433
P1476
PKD1 phosphorylation-dependent ...... ymal transition and metastasis
@en
P2093
Guangwen Ren
Hanqiu Zheng
Hui-Yun Wang
Mario Andres Blanco
Minhong Shen
Peter Storz
Wenyang Li
Yibin Kang
Yin-Lian Zha
P2860
P304
P3181
P356
10.1016/J.CCR.2014.07.022
P407
P50
P577
2014-09-08T00:00:00Z