Yes and PI3K bind CD95 to signal invasion of glioblastomaRAF inhibitors activate the MAPK pathway by relieving inhibitory autophosphorylationOncogenic ERBB3 mutations in human cancersVEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complexBlocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growthFunction of BRCA1 in the DNA damage response is mediated by ADP-ribosylationPhosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cellsNucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradationHMGA2 induces pituitary tumorigenesis by enhancing E2F1 activityFoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesisSIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activityProteasome inhibitors evoke latent tumor suppression programs in pro-B MLL leukemias through MLL-AF4Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress responseDisruption of CRAF-mediated MEK activation is required for effective MEK inhibition in KRAS mutant tumorsEpidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancersSIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancerPhosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligaseDouble antiangiogenic protein, DAAP, targeting VEGF-A and angiopoietins in tumor angiogenesis, metastasis, and vascular leakageSmall molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastomaASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repressionTargeted disruption of heparan sulfate interaction with hepatocyte and vascular endothelial growth factors blocks normal and oncogenic signalingURI is an oncogene amplified in ovarian cancer cells and is required for their survivalCD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growthAngiopoietin-like 4 protein elevates the prosurvival intracellular O2(-):H2O2 ratio and confers anoikis resistance to tumorsHER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitorsThe Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loopCBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesisOxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG IslandsA systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cellsSumoylation pathway is required to maintain the basal breast cancer subtypeMutant Gq/11 promote uveal melanoma tumorigenesis by activating YAPA "twist box" code of p53 inactivation: twist box: p53 interaction promotes p53 degradationA higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcriptionJARID1B is a luminal lineage-driving oncogene in breast cancerPharmacological inhibition of BMK1 suppresses tumor growth through promyelocytic leukemia proteinMatrix metalloproteinase-9 promotes chronic lymphocytic leukemia b cell survival through its hemopexin domainA tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functionsPML/RARalpha targets promoter regions containing PU.1 consensus and RARE half sites in acute promyelocytic leukemiaCCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3Kras(G12D) and Smad4/Dpc4 haploinsufficiency cooperate to induce mucinous cystic neoplasms and invasive adenocarcinoma of the pancreas
P1433
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P1433
description
begutachtete wissenschaftliche Zeitschrift
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peer-reviewed scientific journal
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revista científica
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revue scientifique
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rivista scientifica
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vědecký časopis
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wetenschappelijk tijdschrift van Cell Press
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рецензований науковий журнал
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वैज्ञानिक पत्रिका
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name
Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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type
label
Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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prefLabel
Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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Cancer Cell
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P243
P3181
P4616
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P1055
P1058
P1144
2001215081
P1156
P1159
P123
P1250
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P1476
Cancer Cell
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