The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication
about
Activation of nucleotide oligomerization domain 2 (NOD2) by human cytomegalovirus initiates innate immune responses and restricts virus replicationHuman cytomegalovirus tegument protein pUL83 inhibits IFI16-mediated DNA sensing for immune evasionIFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIVIntrinsic host restriction factors of human cytomegalovirus replication and mechanisms of viral escapeExtracellular vesicles during Herpes Simplex Virus type 1 infection: an inquireExtracellular vesicles from infected cells: potential for direct pathogenesisInnate immune responses to DNA virusesThe Role of Nuclear Antiviral Factors against Invading DNA Viruses: The Immediate Fate of Incoming Viral GenomesInnate immune pattern recognition: a cell biological perspectiveThe inflammasome as a target of modulation by DNA virusesIFI16 restricts HSV-1 replication by accumulating on the hsv-1 genome, repressing HSV-1 gene expression, and directly or indirectly modulating histone modificationsFriend or Foe: Innate Sensing of HIV in the Female Reproductive Tract.APOE*E2 allele delays age of onset in PSEN1 E280A Alzheimer's disease.Quantitative temporal viromics: an approach to investigate host-pathogen interactionInnate nuclear sensor IFI16 translocates into the cytoplasm during the early stage of in vitro human cytomegalovirus infection and is entrapped in the egressing virions during the late stage.Novel roles of cytoplasmic ICP0: proteasome-independent functions of the RING finger are required to block interferon-stimulated gene production but not to promote viral replication.Interferon γ-inducible protein (IFI) 16 transcriptionally regulates type i interferons and other interferon-stimulated genes and controls the interferon response to both DNA and RNA virusesSTING recognition of cytoplasmic DNA instigates cellular defense.Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA.Nuclear DNA sensor IFI16 as circulating protein in autoimmune diseases is a signal of damage that impairs endothelial cells through high-affinity membrane binding.Mesenchymal stem cells detect and defend against gammaherpesvirus infection via the cGAS-STING pathway.The hypoxia-inducible transcription factor ZNF395 is controlled by IĸB kinase-signaling and activates genes involved in the innate immune response and cancer.Nutlin-3-induced redistribution of chromatin-bound IFI16 in human hepatocellular carcinoma cells in vitro is associated with p53 activation.Selected biomarkers as predictive tools in testing efficacy of melatonin and coenzyme Q on propionic acid - induced neurotoxicity in rodent model of autism.Dynamic modulation of HSV chromatin drives initiation of infection and provides targets for epigenetic therapies.Nuclear sensing of viral DNA, epigenetic regulation of herpes simplex virus infection, and innate immunitycGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells.Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 ImmunosuppressionHuman Cytomegalovirus Immediate-Early 1 Protein Rewires Upstream STAT3 to Downstream STAT1 Signaling Switching an IL6-Type to an IFNγ-Like ResponseThe emerging role of nuclear viral DNA sensors.Bacterial Muramyl Dipeptide (MDP) Restricts Human Cytomegalovirus Replication via an IFN-β-Dependent PathwayHuman cytomegalovirus pUL29/28 and pUL38 repression of p53-regulated p21CIP1 and caspase 1 promoters during infection.DNA sensing-independent inhibition of herpes simplex virus 1 replication by DAI/ZBP1Human Cytomegalovirus Infection Upregulates the Mitochondrial Transcription and Translation MachineriesLearning from the messengers: innate sensing of viruses and cytokine regulation of immunity - clues for treatments and vaccines.Molecular characterization of woodchuck IFI16 and AIM2 and their expression in woodchucks infected with woodchuck hepatitis virus (WHV).cGAS-STING Signaling Regulates Initial Innate Control of Cytomegalovirus InfectionNuclear Innate Immune DNA Sensor IFI16 Is Degraded during Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus (KSHV): Role of IFI16 in Maintenance of KSHV Latency.The ubiquitin ligase TRIM27 functions as a host restriction factor antagonized by Mycobacterium tuberculosis PtpA during mycobacterial infection.HIV provides ample PAMPs for innate immune sensing
P2860
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P2860
The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
The intracellular DNA sensor I ...... an cytomegalovirus replication
@ast
The intracellular DNA sensor I ...... an cytomegalovirus replication
@en
The intracellular DNA sensor I ...... an cytomegalovirus replication
@nl
type
label
The intracellular DNA sensor I ...... an cytomegalovirus replication
@ast
The intracellular DNA sensor I ...... an cytomegalovirus replication
@en
The intracellular DNA sensor I ...... an cytomegalovirus replication
@nl
prefLabel
The intracellular DNA sensor I ...... an cytomegalovirus replication
@ast
The intracellular DNA sensor I ...... an cytomegalovirus replication
@en
The intracellular DNA sensor I ...... an cytomegalovirus replication
@nl
P2093
P2860
P921
P3181
P1433
P1476
The intracellular DNA sensor I ...... an cytomegalovirus replication
@en
P2093
Anna Luganini
Deborah Gatti
Giorgio Gribaudo
Grazia Rosaria Gariano
Marco De Andrea
Marisa Gariglio
Matteo Bronzini
Santo Landolfo
Valentina Dell'Oste
P2860
P304
P3181
P356
10.1371/JOURNAL.PPAT.1002498
P407
P577
2012-01-01T00:00:00Z