Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation - Test2 - elhamkhani - TriplyDB

Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation

Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation

http://www.wikidata.org/entity/Q28247398

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IFI16 induction by glucose restriction in human fibroblasts contributes to autophagy through activation of the ATM/AMPK/p53 pathway IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication Interferon-inducible protein 16: insight into the interaction with tumor suppressor p53 The PYRIN domain in signal transduction The nucleic acid-sensing inflammasomes IFI16 restricts HSV-1 replication by accumulating on the hsv-1 genome, repressing HSV-1 gene expression, and directly or indirectly modulating histone modifications IFI16 Preferentially Binds to DNA with Quadruplex Structure and Enhances DNA Quadruplex Formation The mammalian PYHIN gene family: phylogeny, evolution and expression Modeling the role of p53 pulses in DNA damage- induced cell death decision.Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein.Transcriptome analysis of a rotenone model of parkinsonism reveals complex I-tied and -untied toxicity mechanisms common to neurodegenerative diseases.Nutlin-3-induced redistribution of chromatin-bound IFI16 in human hepatocellular carcinoma cells in vitro is associated with p53 activation.Genomic regulation of senescence and innate immunity signaling in the retinal pigment epithelium.IFI16 Expression Is Related to Selected Transcription Factors during B-Cell Differentiation.S-nitrosylation of ERK inhibits ERK phosphorylation and induces apoptosis Nuclear Innate Immune DNA Sensor IFI16 Is Degraded during Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus (KSHV): Role of IFI16 in Maintenance of KSHV Latency.The interferon-inducible HIN-200 gene family in apoptosis and inflammation: implication for autoimmunity.IFI16 is an essential mediator of growth inhibition, but not differentiation, induced by the leukemia inhibitory factor/JAK/STAT pathway in medullary thyroid carcinoma cells.Translational control plays a prominent role in the hepatocytic differentiation of HepaRG liver progenitor cells.Microarray-based detection and expression analysis of new genes associated with drug resistance in ovarian cancer cell lines Cytosolic double-stranded DNA induces nonnecroptotic programmed cell death in trophoblasts via IFI16.A pathologic link between Wilms tumor suppressor gene, WT1, and IFI16.A novel role of the interferon-inducible protein IFI16 as inducer of proinflammatory molecules in endothelial cells.Expression of common chromosomal fragile site genes, WWOX/FRA16D and FHIT/FRA3B is downregulated by exposure to environmental carcinogens, UV, and BPDE but not by IR.Interferon-inducible protein IFIXalpha1 functions as a negative regulator of HDM2.The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.IFI16 restoration in hepatocellular carcinoma induces tumour inhibition via activation of p53 signals and inflammasome.IFI16 reduced expression is correlated with unfavorable outcome in chronic lymphocytic leukemia.MDM2-p53 Interactions in Human Hepatocellular Carcinoma: What Is the Role of Nutlins and New Therapeutic Options?Overexpression of the DNA sensor proteins, absent in melanoma 2 and interferon-inducible 16, contributes to tumorigenesis of oral squamous cell carcinoma with p53 inactivation.The Absent in Melanoma 2-Like Receptor IFN-Inducible Protein 16 as an Inflammasome Regulator in Systemic Lupus Erythematosus: The Dark Side of Sensing Microbes.

P2860

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P2860

Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation

http://www.wikidata.org/entity/Q28247398

description

2004 nî lūn-bûn

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2004 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2004 թվականի մայիսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation

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Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation

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Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation

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type

label

Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation

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Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation

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Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation

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prefLabel

Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation

@ast

Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation

@en

Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation

@nl

P1433

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Journal of Biological Chemistry

P1476

Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation

@en

P2093

Fikret Sahin

http://www.w3.org/2001/XMLSchema#string

Gloria H Su

http://www.w3.org/2001/XMLSchema#string

Jason A Aglipay

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Naoki Maehara

http://www.w3.org/2001/XMLSchema#string

Nobuko Fujiuchi

http://www.w3.org/2001/XMLSchema#string

Sam W Lee

http://www.w3.org/2001/XMLSchema#string

Takao Ohtsuka

http://www.w3.org/2001/XMLSchema#string

Toru Ouchi

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P2860

Functional interaction between p53 and the interferon-inducible nucleoprotein IFI 16

A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway

The human interferon-inducible protein, IFI 16, is a repressor of transcription

Binding of an interferon-inducible protein (p202) to the retinoblastoma protein

Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma

The PYRIN domain: a member of the death domain-fold superfamily

BRCA1 regulates p53-dependent gene expression

IFI16 as a negative regulator in the regulation of p53 and p21(Waf1)

The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

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20339-44

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scholarly article

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912296

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10.1074/JBC.M400344200

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P433

19

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P478

279

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P577

2004-05-07T00:00:00Z

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14990579

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