Repression of promoter activity by CNOT2, a subunit of the transcription regulatory Ccr4-not complex
about
Human Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcriptionComponents of the CCR4-NOT complex function as nuclear hormone receptor coactivators via association with the NRC-interacting Factor NIF-1Cnot1, Cnot2, and Cnot3 maintain mouse and human ESC identity and inhibit extraembryonic differentiationNOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domainInvolvement of the SMRT/NCoR-HDAC3 complex in transcriptional repression by the CNOT2 subunit of the human Ccr4-Not complexNot1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolinCNOT2 depletion disrupts and inhibits the CCR4-NOT deadenylase complex and induces apoptotic cell deathHuman Ccr4-Not complexes contain variable deadenylase subunitsDNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4-Not complex.The Ccr4-Not complex is a key regulator of eukaryotic gene expressionCcr4-Not complex: the control freak of eukaryotic cellsStructure and RNA-binding properties of the Not1-Not2-Not5 module of the yeast Ccr4-Not complexStructure and assembly of the NOT module of the human CCR4-NOT complexInsights into the structure and architecture of the CCR4-NOT complexMultifunctional roles of the mammalian CCR4-NOT complex in physiological phenomena.Interaction of CCR4-NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis.Variant haploinsufficiency and phenotypic non-penetrance in PRPF31-associated retinitis pigmentosa.Divergence of the expression and subcellular localization of CCR4-associated factor 1 (CAF1) deadenylase proteins in Oryza sativa.Transcription factors that influence RNA polymerases I and II: To what extent is mechanism of action conserved?CNOT2 promotes degradation of p62/SQSTM1 as a negative regulator in ATG5 dependent autophagy.CNOT3 is a modifier of PRPF31 mutations in retinitis pigmentosa with incomplete penetrance.VirD5 is required for efficient Agrobacterium infection and interacts with Arabidopsis VIP2.
P2860
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P2860
Repression of promoter activity by CNOT2, a subunit of the transcription regulatory Ccr4-not complex
description
2004 nî lūn-bûn
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2004 թուականի Մարտին հրատարակուած գիտական յօդուած
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2004 թվականի մարտին հրատարակված գիտական հոդված
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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name
Repression of promoter activit ...... on regulatory Ccr4-not complex
@ast
Repression of promoter activit ...... on regulatory Ccr4-not complex
@en
Repression of promoter activit ...... on regulatory Ccr4-not complex
@nl
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label
Repression of promoter activit ...... on regulatory Ccr4-not complex
@ast
Repression of promoter activit ...... on regulatory Ccr4-not complex
@en
Repression of promoter activit ...... on regulatory Ccr4-not complex
@nl
prefLabel
Repression of promoter activit ...... on regulatory Ccr4-not complex
@ast
Repression of promoter activit ...... on regulatory Ccr4-not complex
@en
Repression of promoter activit ...... on regulatory Ccr4-not complex
@nl
P2093
P2860
P356
P1476
Repression of promoter activit ...... on regulatory Ccr4-not complex
@en
P2093
Carin G M Zwartjes
H T Marc Timmers
Sandrine Jayne
P2860
P304
10848-10854
P356
10.1074/JBC.M311747200
P407
P577
2004-01-05T00:00:00Z