Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
about
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cellsHIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxiaEAF2 suppresses hypoxia-induced factor 1α transcriptional activity by disrupting its interaction with coactivator CBP/p300Myeloid translocation gene-16 co-repressor promotes degradation of hypoxia-inducible factor 1SAICAR induces protein kinase activity of PKM2 that is necessary for sustained proliferative signaling of cancer cellsPyruvate Kinase M2: A Potential Target for Regulating InflammationInterplay Between Metabolism and Oncogenic Process: Role of microRNAsThe Role of Oxygen Sensors, Hydroxylases, and HIF in Cardiac Function and DiseaseDysregulated metabolism contributes to oncogenesisProgress toward overcoming hypoxia-induced resistance to solid tumor therapyPyruvate kinase: Function, regulation and role in cancerLactate dehydrogenase A in cancer: a promising target for diagnosis and therapyIs cancer a metabolic disease?Pyruvate kinase M2 at a glanceHypoxia-inducible factors in physiology and medicineImmunometabolism in TuberculosisHypoxia-inducible factor 1 and cardiovascular diseaseFueling immunity: insights into metabolism and lymphocyte functionPyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesisSmall Molecule Activation of PKM2 in Cancer Cells Induces Serine AuxotrophyM2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation.Undercover: gene control by metabolites and metabolic enzymesThe ever-expanding role of HIF in tumour and stromal biologyAdipose tissue dysfunction and its effects on tumor metabolismContribution of metabolic reprogramming to macrophage plasticity and functionMolecular Connections between Cancer Cell Metabolism and the Tumor MicroenvironmentSubstrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling PathwaysA DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effectPHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192Molecular mechanisms of action and therapeutic uses of pharmacological inhibitors of HIF-prolyl 4-hydroxylases for treatment of ischemic diseasesInsulin promotes glucose consumption via regulation of miR-99a/mTOR/PKM2 pathwayMetabolic profiling of hypoxic cells revealed a catabolic signature required for cell survivalSTAT3 negatively regulates thyroid tumorigenesisMUC1-C oncoprotein regulates glycolysis and pyruvate kinase M2 activity in cancer cellsMitochondria and cancerMetabolic reprogramming: a cancer hallmark even warburg did not anticipateHypoxia-regulated mechanisms in the pathogenesis of obesity and non-alcoholic fatty liver disease.Analysis and interpretation of transcriptomic data obtained from extended Warburg effect genes in patients with clear cell renal cell carcinoma.Zinc finger nuclease mediated knockout of ADP-dependent glucokinase in cancer cell lines: effects on cell survival and mitochondrial oxidative metabolism.Proteomic profiling of HBV infected liver biopsies with different fibrotic stages.
P2860
Q21133953-03533AF2-6432-421A-A284-D6BA88A650A5Q24294721-D353ECF9-8818-48D8-81F2-0DA7EDE7B543Q24319939-6D279B5E-8FD2-4229-80D2-6382AFE31E61Q24337524-6218A40C-BA8D-4DC7-BE37-4A52C011142AQ24338861-5DD0614F-25BD-4811-9B84-73D53F190885Q26752535-F8810E9D-D75F-43A4-BD91-5FA31279514AQ26770381-7B11AF7B-3F6B-41A6-8F53-DC856AFA2C3AQ26780548-09351FF6-5417-45CC-80D2-501175BE035EQ26784630-7DD680AB-CEBB-43A4-8C2F-1A0287C41347Q26796405-6A53A8DB-C0A3-4D37-BB95-A5DE71556031Q26798084-7A2C2E05-AF7D-4385-BC16-86865FBCE2D0Q26851585-B8827AEF-0445-4522-BF20-5F3102F8A2DCQ26852241-2B4E3386-00F1-4C87-859F-ACFF29589F11Q27005722-396D5AA8-6B84-4811-88DB-551741B3F524Q27013770-D91AD3EA-D7F5-49AD-8F06-1DC3B44A552EQ27021247-6C24E785-79CE-467B-908D-D720961BC83EQ27023291-81479AA9-4276-48C8-A1CC-C3262A2542BDQ27025284-86D993D9-B7B1-405C-957C-6971D2B831FBQ27671695-B84A5578-8671-4388-AA92-D00687BD17A8Q27673508-24D5B372-3B75-4C30-ADCE-4C42AF45BE9DQ27677066-67E3280D-36F0-49CB-A989-7405C3E1A80FQ28072281-DB0338EB-1BBB-4B26-BEBF-BF163022F02AQ28079015-13FDBCB8-E9AD-41F5-9376-865124F767D9Q28080748-94E104A3-8539-4E67-928E-A1CA7DF3F921Q28080959-670BD8EF-9A13-4362-B45B-E11685E87AE4Q28081657-61C42569-4D40-48C2-BD6F-091DF260131CQ28116317-BC29B336-F97E-4198-94AB-0ADA4C0A003CQ28237387-17A314D9-EA2F-47F6-B8DD-2BF888BA651DQ28296254-4DD0DAC6-CB14-4CFE-BD84-6321DB336436Q28297656-03115A06-A778-4084-9868-F473CE7FD502Q28384176-FD603C94-132F-4AA1-98F8-7B99D2FD1E8DQ28476795-B0F99F20-18B2-4493-9093-3D08F4E9C96FQ28505424-CE6C2CDD-A1D3-44CF-A71C-1C6204FE38A4Q28742196-DCC6E5D3-F0A9-47CA-87D1-2063251A97AFQ29616610-34C25F7D-0567-4A84-8D32-6DF529FFB98EQ29617612-87133323-6319-43F4-9583-7403F00741CDQ30251565-02C867DA-509F-4FE3-A0ED-447372FB16BAQ30928926-8D18D373-C89B-4EE6-B02A-9BF2660473DBQ31120020-8AC8F42F-C5E2-47F1-A821-7C432327ED46Q33587550-C2E2C46C-2208-4755-9994-5301929E9AE5
P2860
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
@ast
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
@en
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
@en-gb
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
@nl
type
label
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
@ast
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
@en
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
@en-gb
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
@nl
prefLabel
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
@ast
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
@en
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
@en-gb
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
@nl
P2093
P2860
P3181
P1433
P1476
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
@en
P2093
Hongxia Hu
Matthew Knabel
Robert N Cole
Robert O'Meally
Ryan Chang
P2860
P304
P3181
P356
10.1016/J.CELL.2011.03.054
P407
P577
2011-05-27T00:00:00Z