Evidence for three distinct D proteins, which react differentially with anti-Sm autoantibodies, in the cores of the major snRNPs U1, U2, U4/U6 and U5
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cDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: evidence for a direct D1-D2 interactionThe 20kD protein of human [U4/U6.U5] tri-snRNPs is a novel cyclophilin that forms a complex with the U4/U6-specific 60kD and 90kD proteinsHomodimerization of the human U1 snRNP-specific protein CSnurportin1, an m3G-cap-specific nuclear import receptor with a novel domain structuresnRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactionsThe association of the U1-specific 70K and C proteins with U1 snRNPs is mediated in part by common U snRNP proteinspICln inhibits snRNP biogenesis by binding core spliceosomal proteinsSymmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B' and the Sm-like protein LSm4, and their interaction with the SMN protein.Evolutionary conservation of the U7 small nuclear ribonucleoprotein in Drosophila melanogaster.The methylosome, a 20S complex containing JBP1 and pICln, produces dimethylarginine-modified Sm proteinsThe U1 small nuclear ribonucleoprotein (snRNP) 70K protein is transported independently of U1 snRNP particles via a nuclear localization signal in the RNA-binding domainIdentification of an snRNP-associated kinase activity that phosphorylates arginine/serine rich domains typical of splicing factorsMutational analysis of the PRP4 protein of Saccharomyces cerevisiae suggests domain structure and snRNP interactions.Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins.Transcriptional pulse-chase analysis reveals a role for a novel snRNP-associated protein in the manufacture of spliceosomal snRNPs.The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D1 and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for anti-Sm autoantibodiesm3G cap hypermethylation of U1 small nuclear ribonucleoprotein (snRNP) in vitro: evidence that the U1 small nuclear RNA-(guanosine-N2)-methyltransferase is a non-snRNP cytoplasmic protein that requires a binding site on the Sm core domainThe Drosophila gene for antizyme requires ribosomal frameshifting for expression and contains an intronic gene for snRNP Sm D3 on the opposite strand.Identification of a new Schistosoma mansoni SMYB1 partner: putative roles in RNA metabolism.Isolation of U3 snoRNP from CHO cells: a novel 55 kDa protein binds to the central part of U3 snoRNAAutoantibodies to survival of motor neuron complex in patients with polymyositis: immunoprecipitation of D, E, F, and G proteins without other components of small nuclear ribonucleoproteins.Rare scleroderma autoantibodies to the U11 small nuclear ribonucleoprotein and to the trimethylguanosine cap of U small nuclear RNAsEvidence that the 60-kDa protein of 17S U2 small nuclear ribonucleoprotein is immunologically and functionally related to the yeast PRP9 splicing factor and is required for the efficient formation of prespliceosomes.Structurally related but functionally distinct yeast Sm D core small nuclear ribonucleoprotein particle proteins.Small nuclear ribonucleoprotein (RNP) U2 contains numerous additional proteins and has a bipartite RNP structure under splicing conditionsMolecular characterization of a novel, widespread nuclear protein that colocalizes with spliceosome components.Structural availability influences the capacity of autoantigenic epitopes to induce a widespread lupus-like autoimmune response.Affinity purification of Trypanosoma brucei small nuclear ribonucleoproteins reveals common and specific protein components.Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism.Spliceosomal U snRNP core assembly: Sm proteins assemble onto an Sm site RNA nonanucleotide in a specific and thermodynamically stable mannerThe determinants for Sm protein binding to Xenopus U1 and U5 snRNAs are complex and non-identical.Expression, localization and clinical application of exogenous Smith proteins D1 in gene transfected HEp-2 cells.A novel epitope on the C-terminus of SmD1 is recognized by the majority of sera from patients with systemic lupus erythematosus.Evolutionary conservation of the spliceosomal protein, U2B''.Polypeptide components of Drosophila small nuclear ribonucleoprotein particles.Caspase-mediated cleavage of the U snRNP-associated Sm-F protein during apoptosis.Practical evaluation of methods for detection and specificity of autoantibodies to extractable nuclear antigens.In vitro reconstitution of mammalian U2 and U5 snRNPs active in splicing: Sm proteins are functionally interchangeable and are essential for the formation of functional U2 and U5 snRNPs.Nucleo-cytoplasmic transport of U snRNPs: definition of a nuclear location signal in the Sm core domain that binds a transport receptor independently of the m3G cap.The mammalian homologue of Prp16p is overexpressed in a cell line tolerant to Leflunomide, a new immunoregulatory drug effective against rheumatoid arthritis.
P2860
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P2860
Evidence for three distinct D proteins, which react differentially with anti-Sm autoantibodies, in the cores of the major snRNPs U1, U2, U4/U6 and U5
description
1990 nî lūn-bûn
@nan
1990 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Evidence for three distinct D ...... or snRNPs U1, U2, U4/U6 and U5
@ast
Evidence for three distinct D ...... or snRNPs U1, U2, U4/U6 and U5
@en
Evidence for three distinct D ...... or snRNPs U1, U2, U4/U6 and U5
@en-gb
Evidence for three distinct D ...... or snRNPs U1, U2, U4/U6 and U5
@nl
type
label
Evidence for three distinct D ...... or snRNPs U1, U2, U4/U6 and U5
@ast
Evidence for three distinct D ...... or snRNPs U1, U2, U4/U6 and U5
@en
Evidence for three distinct D ...... or snRNPs U1, U2, U4/U6 and U5
@en-gb
Evidence for three distinct D ...... or snRNPs U1, U2, U4/U6 and U5
@nl
prefLabel
Evidence for three distinct D ...... or snRNPs U1, U2, U4/U6 and U5
@ast
Evidence for three distinct D ...... or snRNPs U1, U2, U4/U6 and U5
@en
Evidence for three distinct D ...... or snRNPs U1, U2, U4/U6 and U5
@en-gb
Evidence for three distinct D ...... or snRNPs U1, U2, U4/U6 and U5
@nl
P2093
P2860
P921
P356
P1476
Evidence for three distinct D ...... or snRNPs U1, U2, U4/U6 and U5
@en
P2093
P2860
P304
P356
10.1093/NAR/18.22.6475
P407
P577
1990-11-25T00:00:00Z