Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity
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Glycogen synthase kinase-3β is a crucial mediator of signal-induced RelB degradationRegulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom countsA Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced deathUpregulation of RGS4 expression by IL-1beta in colonic smooth muscle is enhanced by ERK1/2 and p38 MAPK and inhibited by the PI3K/Akt/GSK3beta pathwayThe Regulation of NF-κB Subunits by PhosphorylationGSK-3 as potential target for therapeutic intervention in cancerAnalysis of the RelA:CBP/p300 Interaction Reveals Its Involvement in NF-κB-Driven TranscriptionNatural Compound Histone Deacetylase Inhibitors (HDACi): Synergy with Inflammatory Signaling Pathway Modulators and Clinical Applications in CancerCrosstalk between Wnt/β-Catenin and NF-κB Signaling Pathway during InflammationTo be an ally or an adversary in bladder cancer: the NF-κB story has not unfoldedBasic principles and emerging concepts in the redox control of transcription factorsBiomechanical signals suppress TAK1 activation to inhibit NF-kappaB transcriptional activation in fibrochondrocytesDisruption of IkappaB kinase (IKK)-mediated RelA serine 536 phosphorylation sensitizes human multiple myeloma cells to histone deacetylase (HDAC) inhibitors.GCN5 is a required cofactor for a ubiquitin ligase that targets NF-kappaB/RelAIkappaB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300.GSK-3: Functional Insights from Cell Biology and Animal Models.The p65 subunit of NF-κB inhibits COL1A1 gene transcription in human dermal and scleroderma fibroblasts through its recruitment on promoter by protein interaction with transcriptional activators (c-Krox, Sp1, and Sp3).GSK3β controls epithelial-mesenchymal transition and tumor metastasis by CHIP-mediated degradation of SlugPeptide arrays for kinase profiling.Effects of nuclear factor-kappaB on rat hepatocyte regeneration and apoptosis after 70% portal branch ligation.Primers on molecular pathways. The glycogen synthase kinase-3betaGlycogen synthase kinase-3 inhibition disrupts nuclear factor-kappaB activity in pancreatic cancer, but fails to sensitize to gemcitabine chemotherapyCNBP acts as a key transcriptional regulator of sustained expression of interleukin-6.Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatasesInnate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3).GSK-3 represses growth factor-inducible genes by inhibiting NF-kappaB in quiescent cells.Inhibition of human immunodeficiency virus type-1 by cdk inhibitorsCurrent technologies to identify protein kinase substrates in high throughputProfiling insulin like factor 3 (INSL3) signaling in human osteoblasts.A screen for transcription factor targets of glycogen synthase kinase-3 highlights an inverse correlation of NFκB and androgen receptor signaling in prostate cancerGlycogen synthase kinase-3β inactivation inhibits tumor necrosis factor-α production in microglia by modulating nuclear factor κB and MLK3/JNK signaling cascadesCyclin-dependent kinase 6 phosphorylates NF-κB P65 at serine 536 and contributes to the regulation of inflammatory gene expression.Glycogen synthase kinase 3 protein kinase activity is frequently elevated in human non-small cell lung carcinoma and supports tumour cell proliferation.Heterologous down-regulation of angiotensin type 1 receptors by purinergic P2Y2 receptor stimulation through S-nitrosylation of NF-kappaB.Phosphorylation of NF-kappaB p65 at Ser468 controls its COMMD1-dependent ubiquitination and target gene-specific proteasomal eliminationWhat Are the bona fide GSK3 Substrates?Deregulation of the phosphatidylinositol-3 kinase signaling cascade is associated with neurodegeneration in Npc1-/- mouse brain.The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways.The Nurr1 Activator 1,1-Bis(3'-Indolyl)-1-(p-Chlorophenyl)Methane Blocks Inflammatory Gene Expression in BV-2 Microglial Cells by Inhibiting Nuclear Factor κB
P2860
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P2860
Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Phosphorylation of serine 468 ...... s basal p65 NF-kappaB activity
@ast
Phosphorylation of serine 468 ...... s basal p65 NF-kappaB activity
@en
Phosphorylation of serine 468 ...... s basal p65 NF-kappaB activity
@en-gb
Phosphorylation of serine 468 ...... s basal p65 NF-kappaB activity
@nl
type
label
Phosphorylation of serine 468 ...... s basal p65 NF-kappaB activity
@ast
Phosphorylation of serine 468 ...... s basal p65 NF-kappaB activity
@en
Phosphorylation of serine 468 ...... s basal p65 NF-kappaB activity
@en-gb
Phosphorylation of serine 468 ...... s basal p65 NF-kappaB activity
@nl
prefLabel
Phosphorylation of serine 468 ...... s basal p65 NF-kappaB activity
@ast
Phosphorylation of serine 468 ...... s basal p65 NF-kappaB activity
@en
Phosphorylation of serine 468 ...... s basal p65 NF-kappaB activity
@en-gb
Phosphorylation of serine 468 ...... s basal p65 NF-kappaB activity
@nl
P2093
P921
P3181
P356
P1476
Phosphorylation of serine 468 ...... s basal p65 NF-kappaB activity
@en
P2093
Anneke Dörrie
Holger Buss
Klaus Resch
M Lienhard Schmitz
Ronald Frank
P304
P3181
P356
10.1074/JBC.C400442200
P407
P577
2004-11-26T00:00:00Z