about
sameAs
P129
GSK3p-S9/21-GSK3AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complexRUNX2:GSK3Bp-3S-RUNX2:GSK3BPolyUb;p-3S-RUNX2:GSK3Bp-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complexFRAT1;2:GSK3betap-S33;S37;T41;S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complexp-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complexp-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complexGSK3B:AXIN1Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 betaConstitutive phosphorylation by GSK3Phosphorylation of CRMPs by GSK3betaAPC truncation mutants have impaired AXIN bindingAXIN mutants destabilize the destruction complexTruncated AMER1 mutants destabilize the destruction complexRUNX2 binds GSK3BB-WICH complex binds rDNA promoterAssembly of the destruction complexFRAT proteins bind GSK3betaGSK3 phosphorylates p-GLI3GSK3 phosphorylates p-GLI2Proteasome degrades polyubiquitinated RUNX2_R-HSA-8939902
P527
P688
NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3β resulting in the stabilization of MYCN in human neuroblastomasPhosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase ASubstitution of a glycogen synthase kinase-3beta phosphorylation site in presenilin 1 separates presenilin function from beta-catenin signalingCaveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-cateninThe low density lipoprotein receptor-related protein 6 interacts with glycogen synthase kinase 3 and attenuates activityPTEN differentially regulates expressions of ICAM-1 and VCAM-1 through PI3K/Akt/GSK-3β/GATA-6 signaling pathways in TNF-α-activated human endothelial cellsErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells.Primed phosphorylation of tau at Thr231 by glycogen synthase kinase 3beta (GSK3beta) plays a critical role in regulating tau's ability to bind and stabilize microtubulesRegulation of endothelial cell cytoskeletal reorganization by a secreted frizzled-related protein-1 and frizzled 4- and frizzled 7-dependent pathway: role in neovessel formationPhosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A-cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinaseDual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transitionPhosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activityEndoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3betaRegulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/AktNuclear export of NF-ATc enhanced by glycogen synthase kinase-3The EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin.Association of GSK3beta polymorphisms with brain structural changes in major depressive disorderConstitutive activation of the Wnt canonical pathway in mantle cell lymphomaImportance of autophosphorylation at Ser186 in the A-loop of salt inducible kinase 1 for its sustained kinase activityBinding of GSK3beta to the APC-beta-catenin complex and regulation of complex assemblyGlycogen synthase kinase 3: more than a namesakeIdentification of WNT/beta-CATENIN signaling pathway components in human cumulus cellsDownregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 betaIdentification of an antiapoptotic protein complex at death receptorsGSK-3beta-regulated interaction of BICD with dynein is involved in microtubule anchorage at centrosomeThe adenomatous polyposis coli protein (APC) exists in two distinct soluble complexes with different functionsControl of beta-catenin phosphorylation/degradation by a dual-kinase mechanismA WNT1-regulated developmental gene cascade prevents dopaminergic neurodegeneration in adult En1(+/-) miceThe importance of Wnt signalling for neurodegeneration in Parkinson's diseaseGSK3beta and endoplasmic reticulum stress mediate rotenone-induced death of SK-N-MC neuroblastoma cellsGSK3B polymorphisms alter transcription and splicing in Parkinson's diseaseThe protease Omi regulates mitochondrial biogenesis through the GSK3β/PGC-1α pathwayA role for Akt and glycogen synthase kinase-3 as integrators of dopamine and serotonin neurotransmission in mental healthGSKIP is homologous to the Axin GSK3beta interaction domain and functions as a negative regulator of GSK3beta.Rictor Undergoes Glycogen Synthase Kinase 3 (GSK3)-dependent, FBXW7-mediated Ubiquitination and Proteasomal Degradation.Microtubule stabilization specifies initial neuronal polarization.Identification of domains responsible for ubiquitin-dependent degradation of dMyc by glycogen synthase kinase 3beta and casein kinase 1 kinasesGSKIP, an inhibitor of GSK3beta, mediates the N-cadherin/beta-catenin pool in the differentiation of SH-SY5Y cells.Glycogen synthase kinase 3 alpha and 3 beta do not colocalize with neurofibrillary tangles.Activation of glycogen synthase kinase-3 inhibits long-term potentiation with synapse-associated impairments.
P921
Q50255942-4634575D-4ED4-4C1F-98DD-50288456AF54Q50255943-05196DCE-5CEA-492E-A73E-02EBEAF6039EQ50256117-F4177E5C-96DC-4624-A3AD-8782ED8A7F64Q50258443-72236F6D-D320-48F1-8402-067D3AC193A8Q50258444-435B2694-44A9-47CF-A46D-9D6045353007Q50258451-15AC65D0-8C15-4B3E-B347-B7BC7E6E8DE1Q50273400-739992CC-04D4-4090-A4E5-DCA261438CCDQ50273408-A3394884-226E-456B-969F-F3DA6632BC3CQ50273415-BDFE4A48-4A4D-4144-B942-B7ECC879B2BCQ50273416-765655F0-3C26-45F7-9EC4-9FE7062BD7B0Q50273421-74944BAF-45E0-40A8-AC9F-CD582853D8F7Q50273474-B11B8582-1F7F-4420-B0F0-F4F6EA751285Q50286085-905A54A1-AF92-476F-BCD8-F1E6B059409EQ50286619-75E0E208-684E-4981-91D0-D604863B6763Q50287513-4AE59178-32D1-4D11-8E82-45ABAF42C343Q50288857-6920354B-8DB4-4936-9591-006C9BDF6B6EQ50288860-719BDC84-1537-4D77-9234-3694DED128B7Q50288863-CFDF5D0D-7A4C-4F81-9E68-90FB4CD470B0Q50290649-7DADE9E0-6755-4001-9E2E-22B74AA0685DQ50290970-1DE06795-8F26-41EB-BC96-6B2429860937Q50298707-576A731D-F8CA-4952-BFF2-7D713EFCE911Q50298738-FD1F8CD4-72F1-4561-A691-7074B71E291FQ50298929-97249250-4900-43D8-A6BE-E7FF8B957CECQ50298942-9E125A9B-062F-42F7-866C-2AB170A6E94DQ56858355-23A9D95F-339D-4C89-BF60-69EE2985A250
P527
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in GSK3B
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
GSK3B
@de
GSK3B
@nl
GSK3B
@pt
GSK3B
@sv
Glycogen synthase kinase 3 beta
@en
type
label
GSK3B
@de
GSK3B
@nl
GSK3B
@pt
GSK3B
@sv
Glycogen synthase kinase 3 beta
@en
altLabel
2.7.11.1
@en
GSK-3 beta
@en
GSK3B
@en
GSK3beta isoform
@en
glycogen synthase kinase-3 beta
@en
serine/threonine-protein kinase GSK3B
@en
prefLabel
GSK3B
@de
GSK3B
@nl
GSK3B
@pt
GSK3B
@sv
Glycogen synthase kinase 3 beta
@en
P637
P638
P680
P681
P682
P705
P352
P486
P6366
P129
P2888
P31
P352
P486
D000071679
P591
P6366
P637
NP_001139628
NP_001341525
XP_006713673
P638
P680
P681
P682
P702
P703
P705
ENSP00000264235
ENSP00000324806
ENSP00000497956