Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics
about
Unstable microtubule capture at kinetochores depleted of the centromere-associated protein CENP-F.A cryptic TOG domain with a distinct architecture underlies CLASP-dependent bipolar spindle formationMammalian CLASPs are required for mitotic spindle organization and kinetochore alignmentMammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function.CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelityCLIPs and CLASPs and cellular dynamicsMAP4 and CLASP1 operate as a safety mechanism to maintain a stable spindle position in mitosisCLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortexCLASP2 Has Two Distinct TOG Domains That Contribute Differently to Microtubule DynamicsCLASP modulates microtubule-cortex interaction during self-organization of acentrosomal microtubules.Drosophila CLASP is required for the incorporation of microtubule subunits into fluxing kinetochore fibresSpatial regulation of CLASP affinity for microtubules by Rac1 and GSK3beta in migrating epithelial cellsFunctional importance of the anaphase-promoting complex-Cdh1-mediated degradation of TMAP/CKAP2 in regulation of spindle function and cytokinesis.Reconstituting the kinetochore–microtubule interface: what, why, and howTPX2 phosphorylation maintains metaphase spindle length by regulating microtubule flux.Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability.Orbit/CLASP is required for myosin accumulation at the cleavage furrow in Drosophila male meiosisThe fission yeast kinetochore component Spc7 associates with the EB1 family member Mal3 and is required for kinetochore-spindle associationCLIP-170 facilitates the formation of kinetochore-microtubule attachments.Poleward tubulin flux in spindles: regulation and function in mitotic cells.Xorbit/CLASP links dynamic microtubules to chromosomes in the Xenopus meiotic spindle.Stabilization of microtubule dynamics at anaphase onset promotes chromosome segregation.A model for the regulatory network controlling the dynamics of kinetochore microtubule plus-ends and poleward flux in metaphaseMotor-independent targeting of CLASPs to kinetochores by CENP-E promotes microtubule turnover and poleward flux.Molecular control of kinetochore-microtubule dynamics and chromosome oscillationsMultiple domains of human CLASP contribute to microtubule dynamics and organization in vitro and in Xenopus egg extracts.Multisite phosphorylation disrupts arginine-glutamate salt bridge networks required for binding of cytoplasmic linker-associated protein 2 (CLASP2) to end-binding protein 1 (EB1).Modulation of Golgi-associated microtubule nucleation throughout the cell cycleA mitotic SKAP isoform regulates spindle positioning at astral microtubule plus ends.A TOGL domain specifically targets yeast CLASP to kinetochores to stabilize kinetochore microtubules.The kinetochoreDynamic regulation of Oct1 during mitosis by phosphorylation and ubiquitination.Parallel genetic and proteomic screens identify Msps as a CLASP-Abl pathway interactor in Drosophila.Aurora B kinase controls the targeting of the Astrin-SKAP complex to bioriented kinetochores.CLASP promotes microtubule rescue by recruiting tubulin dimers to the microtubule.Orbit/CLASP is required for germline cyst formation through its developmental control of fusomes and ring canals in Drosophila malesLength-dependent anisotropic scaling of spindle shapeMitotic spindle form and functionMicrotubule encounter-based catastrophe in Arabidopsis cortical microtubule arraysAcentrosomal spindle assembly and chromosome segregation during oocyte meiosis
P2860
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P2860
Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Human CLASP1 is an outer kinet ...... s spindle microtubule dynamics
@ast
Human CLASP1 is an outer kinet ...... s spindle microtubule dynamics
@en
Human CLASP1 is an outer kinet ...... s spindle microtubule dynamics
@en-gb
Human CLASP1 is an outer kinet ...... s spindle microtubule dynamics
@nl
type
label
Human CLASP1 is an outer kinet ...... s spindle microtubule dynamics
@ast
Human CLASP1 is an outer kinet ...... s spindle microtubule dynamics
@en
Human CLASP1 is an outer kinet ...... s spindle microtubule dynamics
@en-gb
Human CLASP1 is an outer kinet ...... s spindle microtubule dynamics
@nl
prefLabel
Human CLASP1 is an outer kinet ...... s spindle microtubule dynamics
@ast
Human CLASP1 is an outer kinet ...... s spindle microtubule dynamics
@en
Human CLASP1 is an outer kinet ...... s spindle microtubule dynamics
@en-gb
Human CLASP1 is an outer kinet ...... s spindle microtubule dynamics
@nl
P50
P921
P3181
P1433
P1476
Human CLASP1 is an outer kinet ...... s spindle microtubule dynamics
@en
P2093
Conly L Rieder
Elizabeth A L Fairley
P304
P3181
P356
10.1016/S0092-8674(03)00465-3
P407
P577
2003-06-27T00:00:00Z