Constitutive induction of p-Erk1/2 accompanied by reduced activities of protein phosphatases 1 and 2A and MKP3 due to reactive oxygen species during cellular senescence
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Neuroprotective and anti-inflammatory properties of a coffee component in the MPTP model of Parkinson's diseaseOxidative stress-induced JNK activation contributes to proinflammatory phenotype of aging diabetic mesangial cells.Oxidants positively or negatively regulate nuclear factor kappaB in a context-dependent mannerGenetic demonstration of a redundant role of extracellular signal-regulated kinase 1 (ERK1) and ERK2 mitogen-activated protein kinases in promoting fibroblast proliferationA simple method to systematically study oxidatively modified proteins in biological samples and its applicationsMechanisms of MDMA (ecstasy)-induced oxidative stress, mitochondrial dysfunction, and organ damage.p90 activation contributes to cerebral ischemic damage via phosphorylation of Na+/H+ exchanger isoform 1.Sterol regulatory element-binding protein (SREBP)-1-mediated lipogenesis is involved in cell senescence.FRA1 is a determinant for the difference in RAS-induced transformation between human and rat fibroblasts.Arsenite Acutely Decreases Nitric Oxide Production via the ROS-Protein Phosphatase 1-Endothelial Nitric Oxide Synthase-Thr(497) Signaling CascadePeripheral residence of naïve CD4 T cells induces MHC class II-dependent alterations in phenotype and function.Targeting SET/I(2)PP2A oncoprotein functions as a multi-pathway strategy for cancer therapyTSH signaling overcomes B-RafV600E-induced senescence in papillary thyroid carcinogenesis through regulation of DUSP6.Cellular senescence in the glaucomatous outflow pathwayLong-range signaling by phosphoprotein waves arising from bistability in protein kinase cascades.Contractile Function During Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation.Peroxisomes and aging.Regulations of Reversal of Senescence by PKC Isozymes in Response to 12-O-Tetradecanoylphorbol-13-Acetate via Nuclear Translocation of pErk1/2.Phosphorylated extracellular signal-regulated protein kinases 1 and 2 phosphorylate Sp1 on serine 59 and regulate cellular senescence via transcription of p21Sdi1/Cip1/Waf1.NADPH oxidase-dependent redox signaling in TGF-β-mediated fibrotic responses.ERK and cell death: mechanisms of ERK-induced cell death--apoptosis, autophagy and senescence.Inflammasome priming by lipopolysaccharide is dependent upon ERK signaling and proteasome function.The effect of ageing on macrophage Toll-like receptor-mediated responses in the fight against pathogens.DNA double-strand break - induced pro-survival signaling.Reactive oxygen species-mediated therapeutic control of bladder cancer.Clinical significance of cancerous inhibitor of protein phosphatase 2A in human cancers.Increased expression of c-Fos by extracellular signal-regulated kinase activation under sustained oxidative stress elicits BimEL upregulation and hepatocyte apoptosis.Inhibitory role of peroxiredoxin II (Prx II) on cellular senescence.Suppression of B-Raf(V600E) cancers by MAPK hyper-activationInflammation-induced radioresistance is mediated by ROS-dependent inactivation of protein phosphatase 1 in non-small cell lung cancer cells.Alcohol drives S-nitrosylation and redox activation of protein phosphatase 1, causing bovine airway cilia dysfunction.Survive or thrive: tradeoff strategy for cellular senescence.Dual-specificity phosphatase DUSP6 has tumor-promoting properties in human glioblastomas.Restoration of peroxisomal catalase import in a model of human cellular aging.Identification of a protective role for protein phosphatase 1cgamma1 against oxidative stress-induced vascular smooth muscle cell apoptosis.B cell translocation gene 2 enhances susceptibility of HeLa cells to doxorubicin-induced oxidative damage.NADPH oxidase 4 mediates TGF-β-induced smooth muscle α-actin via p38MAPK and serum response factorDifferent mechanisms account for extracellular-signal regulated kinase activation in distinct brain regions following global ischemia and reperfusionHSP70 deficiency results in activation of c-Jun N-terminal Kinase, extracellular signal-regulated kinase, and caspase-3 in hyperosmolarity-induced apoptosis.Dehydroepiandrosterone augments sensitivity to gamma-ray irradiation in human H4 neuroglioma cells through down-regulation of Akt signaling.
P2860
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P2860
Constitutive induction of p-Erk1/2 accompanied by reduced activities of protein phosphatases 1 and 2A and MKP3 due to reactive oxygen species during cellular senescence
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
name
Constitutive induction of p-Er ...... ies during cellular senescence
@ast
Constitutive induction of p-Er ...... ies during cellular senescence
@en
Constitutive induction of p-Er ...... ies during cellular senescence
@en-gb
Constitutive induction of p-Er ...... ies during cellular senescence
@nl
type
label
Constitutive induction of p-Er ...... ies during cellular senescence
@ast
Constitutive induction of p-Er ...... ies during cellular senescence
@en
Constitutive induction of p-Er ...... ies during cellular senescence
@en-gb
Constitutive induction of p-Er ...... ies during cellular senescence
@nl
prefLabel
Constitutive induction of p-Er ...... ies during cellular senescence
@ast
Constitutive induction of p-Er ...... ies during cellular senescence
@en
Constitutive induction of p-Er ...... ies during cellular senescence
@en-gb
Constitutive induction of p-Er ...... ies during cellular senescence
@nl
P2093
P2860
P356
P1476
Constitutive induction of p-Er ...... ies during cellular senescence
@en
P2093
Hong Seok Kim
In Hae Kwak
In Kyoung Lim
Myeong-Cheol Song
Tae Jun Park
P2860
P304
P356
10.1074/JBC.M211739200
P407
P577
2003-09-26T00:00:00Z