SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1
about
KAPtain in charge of multiple missions: Emerging roles of KAP1What goes on must come off: phosphatases gate-crash the DNA damage responseA unique SUMO-2-interacting motif within LANA is essential for KSHV latencyhnRNP K coordinates transcriptional silencing by SETDB1 in embryonic stem cellsDNA IR-Double Strand Breaks (DSBs) and cellular response via ATMIdentification of cell-specific targets of sumoylation during mouse spermatogenesis.DNA double-strand breaks promote methylation of histone H3 on lysine 9 and transient formation of repressive chromatin.An arginine-rich motif of ring finger protein 4 (RNF4) oversees the recruitment and degradation of the phosphorylated and SUMOylated Krüppel-associated box domain-associated protein 1 (KAP1)/TRIM28 protein during genotoxic stress.Coordinate to guard: crosstalk of phosphorylation, sumoylation, and ubiquitylation in DNA damage response.KAP1 Is a Host Restriction Factor That Promotes Human Adenovirus E1B-55K SUMO ModificationResistance to DNA-damaging treatment in non-small cell lung cancer tumor-initiating cells involves reduced DNA-PK/ATM activation and diminished cell cycle arrestTRIM28 multi-domain protein regulates cancer stem cell population in breast tumor development.Chromatin dynamics and the repair of DNA double strand breaks.KAP1 protein: an enigmatic master regulator of the genome.DNA double-strand break repair within heterochromatic regions.Reading, writing, and repair: the role of ubiquitin and the ubiquitin-like proteins in DNA damage signaling and repair.URI Regulates KAP1 Phosphorylation and Transcriptional Repression via PP2A Phosphatase in Prostate Cancer Cells.Role of ATM in the formation of the replication compartment during lytic replication of Epstein-Barr virus in nasopharyngeal epithelial cells.Inhibition of CDK1 activity by sumoylation.Proteomic profiling identifies the SIM-associated complex of KSHV-encoded LANA.SUMO binding by the Epstein-Barr virus protein kinase BGLF4 is crucial for BGLF4 function.Phosphoproteomic analysis reveals that PP4 dephosphorylates KAP-1 impacting the DNA damage response.Response to DNA damage: why do we need to focus on protein phosphatases?Role of Protein Phosphatase 1 and Inhibitor of Protein Phosphatase 1 in Nitric Oxide-Dependent Inhibition of the DNA Damage Response in Pancreatic β-Cells.Cross-talk between phosphorylation and SUMOylation regulates transforming activities of an adenoviral oncoprotein.Adeno-associated virus Rep proteins antagonize phosphatase PP1 to counteract KAP1 repression of the latent viral genome.
P2860
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P2860
SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1
description
2010 nî lūn-bûn
@nan
2010 թուականին հրատարակուած գիտական յօդուած
@hyw
2010 թվականին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
SUMOylation of the transcripti ...... and threonine phosphatase PP1
@ast
SUMOylation of the transcripti ...... and threonine phosphatase PP1
@en
SUMOylation of the transcripti ...... and threonine phosphatase PP1
@en-gb
SUMOylation of the transcripti ...... and threonine phosphatase PP1
@nl
type
label
SUMOylation of the transcripti ...... and threonine phosphatase PP1
@ast
SUMOylation of the transcripti ...... and threonine phosphatase PP1
@en
SUMOylation of the transcripti ...... and threonine phosphatase PP1
@en-gb
SUMOylation of the transcripti ...... and threonine phosphatase PP1
@nl
prefLabel
SUMOylation of the transcripti ...... and threonine phosphatase PP1
@ast
SUMOylation of the transcripti ...... and threonine phosphatase PP1
@en
SUMOylation of the transcripti ...... and threonine phosphatase PP1
@en-gb
SUMOylation of the transcripti ...... and threonine phosphatase PP1
@nl
P2093
P2860
P1433
P1476
SUMOylation of the transcripti ...... and threonine phosphatase PP1
@en
P2093
David K Ann
H Helen Lin
Hanqing Chen
Hsiu-Ming Shih
P2860
P356
10.1126/SCISIGNAL.2000781
P407
P50
P577
2010-04-27T00:00:00Z